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Protein Domain : IPR013781

Name  Glycoside hydrolase, catalytic domain Short Name  Glyco_hydro_catalytic_dom
Type  Domain Description  O-Glycosyl hydrolases () are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families [, ]. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site.This entry represents the catalytic TIM beta/alpha barrel common to many different families of glycosyl hydrolases. Structures have beendetermined for several proteins containing this domain, including family 13 glycosyl hydrolases (such as alpha-amylase) [], beta-glycanases [], family 1 glycosyl hydrolases (such as beta-glucosidase) [], type II chitinases [], 1,4-beta-N-acetylmuraminidases [], and beta-N-acetylhexosaminidases [].

Publication Counts Displayer

8 Child Features

DB identifier Name Short Name Type
IPR015883 Glycoside hydrolase family 20, catalytic core Glyco_hydro_20_cat-core Domain
IPR001223 Glycoside hydrolase, family 18, catalytic domain Glyco_hydro18cat Domain
IPR006047 Glycosyl hydrolase, family 13, catalytic domain Glyco_hydro_13_cat_dom Domain
IPR006103 Glycoside hydrolase, family 2, TIM barrel Glyco_hydro_2_TIM Domain
IPR011100 Glycosyl hydrolase family 67 middle Glyco_hydro_67_M Domain
IPR025277 Putative glycohydrolase domain DUF4038 DUF4038 Domain
IPR025275 Putative glycosyl hydrolase domain DUF4015 DUF4015 Domain
IPR001547 Glycoside hydrolase, family 5 Glyco_hydro_5 Domain

8 Contains

DB identifier Name Short Name Type
IPR001579 Glycoside hydrolase, chitinase active site Glyco_hydro_18_chit_AS Active_site
IPR018526 Glycoside hydrolase, family 29, conserved site Glyco_hydro_29_CS Conserved_site
IPR018120 Glycoside hydrolase, family 1, active site Glyco_hydro_1_AS Active_site
IPR019801 Glycoside hydrolase, family 35, conserved site Glyco_hydro_35_CS Conserved_site
IPR006589 Glycosyl hydrolase, family 13, subfamily, catalytic domain Glyco_hydro_13_sub_cat_dom Domain
IPR008270 Glycoside hydrolase, family 25, active site Glyco_hydro_25_AS Active_site
IPR018238 Glycoside hydrolase, family 14, conserved site Glyco_hydro_14_CS Conserved_site
IPR018087 Glycoside hydrolase, family 5, conserved site Glyco_hydro_5_CS Conserved_site

1 Cross References

Identifier
Source . Name

Subject . Primary Identifier
G3DSA:3.20.20.80 GENE3D IPR013781

3 Data Sets

Name URL
Swiss-Prot data set http://ca.expasy.org/sprot
InterPro data set  
InterPro GO Annotation data set  

26 Found In

DB identifier Name Short Name Type
IPR001139 Glycoside hydrolase, family 30 Glyco_hydro_30 Family
IPR001944 Glycoside hydrolase, family 35 Glycoside_Hdrlase_35 Family
IPR001360 Glycoside hydrolase, family 1 Glyco_hydro_1 Family
IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GlgB Family
IPR006046 Alpha amylase Alpha_amylase Family
IPR000514 Glycoside hydrolase, family 39 Glyco_hydro_39 Family
IPR006421 Glycogen debranching enzyme, metazoa Glycogen_debranch_met Family
IPR001286 Glycoside hydrolase, family 59 Glyco_hydro_59 Family
IPR022527 Sucrose phosphorylase, GftA Sucrose_phosphorylase_GftA Family
IPR016377 Sucrose phosphorylase Sucrose_phosphorylase Family
IPR005928 6-phospho-beta-galactosidase 6P-beta-galactosidase Family
IPR012665 Trehalose synthase Trehalose_synth Family
IPR011683 Glycosyl hydrolase family 53 Glyco_hydro_53 Domain
IPR017736 Glycoside hydrolase, family 1, beta-glucosidase Glyco_hydro_1_beta-glucosidase Family
IPR001000 Glycoside hydrolase, family 10 Glyco_hydro_10 Family
IPR003385 Glycoside hydrolase, family 77 Glyco_hydro_77 Family
IPR004886 Glucanosyltransferase Glucanosyltransferase Family
IPR001371 Glycoside hydrolase, family 14B, plant Glyco_hydro_14B_pln Family
IPR000125 Glycoside hydrolase, family 14A, bacterial Glyco_hydro_14A_bac Family
IPR001554 Glycoside hydrolase, family 14 Glyco_hydro_14 Family
IPR000490 Glycoside hydrolase, family 17 Glyco_hydro_17 Family
IPR016714 Mannan endo-1,4-beta-mannosidase Mannan-1_4-b-mannosidase Family
IPR003318 Glycoside hydrolase, family 70, catalytic domain Glyco_hydro70cat Domain
IPR003790 Protein of unknown function DUF187 DUF187 Family
IPR003476 Glycoside hydrolase, family 42 Glyco_hydro_42 Family
IPR013529 Glycoside hydrolase, family 42, N-terminal Glyco_hydro_42_N Domain

1 GO Annotation


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Glycoside hydrolase, catalytic domain   GO:0005975 carbohydrate metabolic process

1 Ontology Annotations


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Glycoside hydrolase, catalytic domain   GO:0005975 carbohydrate metabolic process

1 Parent Features

DB identifier Name Short Name Type
IPR017853 Glycoside hydrolase, superfamily Glycoside_hydrolase_SF Domain

681 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0309782 Q9W303 Drosophila melanogaster
FBpp0071473 Q8MLW8 Drosophila melanogaster
FBpp0085849 Q8T0R7 Drosophila melanogaster
FBpp0078861 Q9VMJ5 Drosophila melanogaster
FBpp0099475 A1ZBH0 Drosophila melanogaster
FBpp0079859 Q9VKE6 Drosophila melanogaster
FBpp0087837 P07192 Drosophila melanogaster
FBpp0290175 Q8T0N3 Drosophila melanogaster
FBpp0087828 Q5U124 Drosophila melanogaster
FBpp0271830 A1Z7F1 Drosophila melanogaster
FBpp0079860 Q8IPA2 Drosophila melanogaster
FBpp0087827 A1Z7E8 Drosophila melanogaster
FBpp0087826 P07191 Drosophila melanogaster
FBpp0087838 P07190 Drosophila melanogaster
FBpp0087831 A1Z7F3 Drosophila melanogaster
FBpp0087836 A1Z7F2 Drosophila melanogaster
FBpp0085777 Q7K173 Drosophila melanogaster
FBpp0085778 A1ZBG9 Drosophila melanogaster
FBpp0075080 Q9VV98 Drosophila melanogaster
FBpp0086263 O18408 Drosophila melanogaster
FBpp0300423 D4G7B1 Drosophila melanogaster
FBpp0307683 Q0KIE6 Drosophila melanogaster
FBpp0078603 Q9VMY5 Drosophila melanogaster
FBpp0071192 Q9W3C4 Drosophila melanogaster
FBpp0080418 Q9V3D4 Drosophila melanogaster
FBpp0086257 Q23997 Drosophila melanogaster
FBpp0079207 Q9VLS0 Drosophila melanogaster
FBpp0072677 Q9W092 Drosophila melanogaster
FBpp0086136 Q5BIJ9 Drosophila melanogaster
FBpp0071472 Q9W2M6 Drosophila melanogaster