modENCODE |  Help |  blog

Protein Domain : IPR004843

Name  Calcineurin-like phosphoesterase domain, apaH type Short Name  Calcineurin-like_PHP_apaH
Type  Domain Description  This domain is found in a diverse range of phosphoesterases [], including bis(5'-nucleosyl)-tetraphosphatase (apaH), nucleotidases, sphingomyelin phosphodiesterases and 2'-3' cAMP phosphodiesterases, as well as nucleases such as bacterial SbcD or archaeal/yeast Mre11. The most conserved regions in this domain centre around the metal chelating residues.

Publication Counts Displayer

1 Child Features

DB identifier Name Short Name Type
IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase Ser/Thr-sp_prot-phosphatase Domain

1 Contains

DB identifier Name Short Name Type
IPR006146 5'-Nucleotidase, conserved site 5'-Nucleotdase_CS Conserved_site

1 Cross References

Identifier
Source . Name

Subject . Primary Identifier
PF00149 PFAM IPR004843

3 Data Sets

Name URL
Swiss-Prot data set http://ca.expasy.org/sprot
InterPro data set  
InterPro GO Annotation data set  

25 Found In

DB identifier Name Short Name Type
IPR000979 Phosphodiesterase MJ0936/Vps29 Phosphodiesterase_MJ0936/Vps29 Family
IPR011160 Sphingomyelin phosphodiesterase Sphingomy_PDE Family
IPR003701 DNA repair protein Mre11 DNA_repair_Mre11 Family
IPR006179 5'-Nucleotidase/apyrase 5_nucleotidase/apyrase Family
IPR011149 DNA polymerase II small subunit, archaeal Pol2_small_arc Family
IPR011152 Phosphoesterase MJ0912 Pesterase_MJ0912 Family
IPR011240 Phosphoesterase-related protein YunD Pesterase_YunD Family
IPR011239 Phosphoesterase cyanobacterial, all2852 Pesterase_cyn Family
IPR011230 Phosphoesterase At2g46880 Pesterase_At2g46 Family
IPR014390 Acid phosphatase, Aspergillus type Acid_Pase_Asper Family
IPR011401 Phosphoesterase, YvnB Pesterase_YvnB Family
IPR017056 Phosphoesterase, HI0762, predicted P-Estase_HI0762_prd Family
IPR017064 Acid sphingomyelinase-like phosphodiesterase, predicted ASM-like_Pdiesterase_prd Family
IPR014578 Predicted phosphoesterase, CT488 type Pesterase_CT488 Family
IPR014577 Uncharacterised conserved protein UCP033093, metallophosphoesterase-type UCP033093_metalloPase Family
IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) ApaH Family
IPR014576 Predicted phosphoesterase, YhaO type Pesterase_YhaO Family
IPR014485 Predicted phosphoesterase, C1039.02 type Pesterase_C1039 Family
IPR012365 Phosphoesterase, lmo2642-related Pesteras_lmo2642 Family
IPR012358 Endopolyphosphatase, Ppn1p-related EndopolyPtase_N1 Family
IPR004376 Conserved hypothetical protein CHP00024, phosphoesterase-like CHP00024_Pesterase-like Family
IPR022507 Metallophosphoesterase, RPA4764 Metallophosphoesterase_RPA4764 Family
IPR022302 Phosphoesterase, putative Phosphoesterase_putative Family
IPR016538 Uncharacterised conserved protein UCP008292, metallophosphoesterase UCP008292_metalloPesterase Family
IPR010138 UDP-2,3-diacylglucosamine hydrolase UDP-diacylglucosamine_Hdrlase Family

1 GO Annotation


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Calcineurin-like phosphoesterase domain, apaH type   GO:0016787 hydrolase activity

1 Ontology Annotations


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Calcineurin-like phosphoesterase domain, apaH type   GO:0016787 hydrolase activity

1 Parent Features

DB identifier Name Short Name Type
IPR029052 Metallo-dependent phosphatase-like Metallo-depent_PP-like Domain

600 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0081606 Q9VH81 Drosophila melanogaster
FBpp0072172 Q8MLP3 Drosophila melanogaster
FBpp0072173 Q9W188 Drosophila melanogaster
FBpp0300565 D6W4U0 Drosophila melanogaster
FBpp0085996 P11612 Drosophila melanogaster
FBpp0071650 Q7KVM5 Drosophila melanogaster
FBpp0079209 Q9VLR9 Drosophila melanogaster
FBpp0071381 Q8T0U6 Drosophila melanogaster
FBpp0305497 P48462 Drosophila melanogaster
FBpp0084026 P48461 Drosophila melanogaster
FBpp0079148 P23696 Drosophila melanogaster
FBpp0079802 Q9XYZ4 Drosophila melanogaster
FBpp0074069 Q27889 Drosophila melanogaster
FBpp0085006 Q9VA77 Drosophila melanogaster
FBpp0288787 Q9VZ33 Drosophila melanogaster
FBpp0288788 Q9VZ32 Drosophila melanogaster
FBpp0086085 A1ZAU0 Drosophila melanogaster
FBpp0076121 Q9VT29 Drosophila melanogaster
FBpp0073263 Q9VZ58 Drosophila melanogaster
FBpp0073264 Q9VZ57 Drosophila melanogaster
FBpp0073262 Q9VZ56 Drosophila melanogaster
FBpp0073834 Q05547 Drosophila melanogaster
FBpp0085094 P48456 Drosophila melanogaster
FBpp0077017 O76932 Drosophila melanogaster
FBpp0075812 Q95TV5 Drosophila melanogaster
FBpp0070883 Q27884 Drosophila melanogaster
FBpp0071719 Q9W2A5 Drosophila melanogaster
FBpp0084990 Q9VA78 Drosophila melanogaster
FBpp0087376 A1Z8A7 Drosophila melanogaster
FBpp0087375 Q8T008 Drosophila melanogaster