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Protein Domain : IPR013320

Name  Concanavalin A-like lectin/glucanase, subgroup Short Name  ConA-like_subgrp
Type  Domain Description  Lectins and glucanases exhibit the common property of reversibly binding to specific complex carbohydrates. The lectins/glucanases are a diverse group of proteins found in a wide range of species from prokaryotes to humans. The different family members all contain a concanavalin A-like domain, which consists of a sandwich of 12-14 beta strands in two sheets with a complex topology. Members of this family are diverse, and include the lectins: legume lectins, cereal lectins, viral lectins, and animal lectins. Plant lectins function in the storage and transport of carbohydrates in seeds, the binding of nitrogen-fixing bacteria to root hairs, the inhibition of fungal growth or insect feeding, and in hormonally regulated plant growth []. Protein members include concanavalin A (Con A), favin, isolectin I, lectin IV, soybean agglutinin and lentil lectin. Animal lectins include the galectins, which are S-type lactose-binding and IgE-binding proteins such as S-lectin, CLC protein, galectin1, galectin2, galectin3 CRD, and Congerin I []. Other members with a Con A-like domain include the glucanases. Bacterial and fungal beta-glucanases, such as Bacillus 1-3,1-4-beta-glucanse, carry out the acid catalysis of beta-glucans found in microorganisms and plants []. Similarly, kappa-Carrageenase degrades kappa-carrageenans from marine red algae cell walls [].

Publication Counts Displayer

10 Child Features

DB identifier Name Short Name Type
IPR001079 Galectin, carbohydrate recognition domain Galectin_CRD Domain
IPR001791 Laminin G domain Laminin_G Domain
IPR008859 Thrombospondin, C-terminal Thrombospondin_C Domain
IPR000757 Glycoside hydrolase, family 16 Glyco_hydro_16 Domain
IPR015344 Vibrio cholerae neuraminidase, lectin-like domain VCNA_lectin-like_dom Domain
IPR001220 Legume lectin domain Legume_lectin_dom Domain
IPR015289 Alpha-L-arabinofuranosidase B, catalytic A-L-arabinofuranosidase_B_cat Domain
IPR012928 Clostridium neurotoxin, receptor binding N-terminal Toxin_rcpt-bd_N Domain
IPR014895 Alginate lyase 2 Alginate_lyase_2 Domain
IPR004124 Glycoside hydrolase, family 33, N-terminal Glyco_hydro_33_N Domain

7 Contains

DB identifier Name Short Name Type
IPR018124 Calreticulin/calnexin, conserved site Calret/calnex_CS Conserved_site
IPR015344 Vibrio cholerae neuraminidase, lectin-like domain VCNA_lectin-like_dom Domain
IPR019825 Legume lectin, beta chain, Mn/Ca-binding site Lectin_legB_Mn/Ca_BS Binding_site
IPR000985 Legume lectin, alpha chain, conserved site Lectin_LegA_CS Conserved_site
IPR010713 Xyloglucan endo-transglycosylase, C-terminal XET_C Domain
IPR008263 Glycoside hydrolase, family 16, active site Glycoside_hydrolase_16_AS Active_site
IPR006558 LamG-like jellyroll fold LamG-like Domain

1 Cross References

Source . Name

Subject . Primary Identifier

2 Data Sets

Name URL
Swiss-Prot data set
InterPro data set  

11 Found In

DB identifier Name Short Name Type
IPR001580 Calreticulin/calnexin Calret/calnex Family
IPR009169 Calreticulin Calreticulin Family
IPR005052 Legume-like lectin Lectin_leg Family
IPR001759 Pentaxin Pentaxin Family
IPR015305 Protein of unknown function DUF1961 DUF1961 Family
IPR008377 Trypanosome sialidase Sialidase_trypan Family
IPR016710 L-type lectin, fungi L-typ_lectin_fun Family
IPR005629 Beta-glucan synthesis-associated, SKN1 SKN1 Family
IPR016455 Xyloglucan endotransglucosylase/hydrolase XET Family
IPR016287 Agarase Agarase Family
IPR000416 Haemagglutinin outer capsid protein VP4 Haemagglutinin_VP4 Family

0 GO Annotation

0 Ontology Annotations

0 Parent Features

581 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0291871 Q8IP51 Drosophila melanogaster
FBpp0293600 R9PY40 Drosophila melanogaster
FBpp0291872 M9MRU0 Drosophila melanogaster
FBpp0099719 Q4ABE9 Drosophila melanogaster
FBpp0099718 Q4ABF0 Drosophila melanogaster
FBpp0080568 O15943 Drosophila melanogaster
FBpp0099721 Q4ABE7 Drosophila melanogaster
FBpp0099720 Q4ABE8 Drosophila melanogaster
FBpp0288558 Q9VM55 Drosophila melanogaster
FBpp0291372 E1JHA6 Drosophila melanogaster
FBpp0310997 B7Z0X3 Drosophila melanogaster
FBpp0310995 B7Z0W8 Drosophila melanogaster
FBpp0310994 Q0KHV9 Drosophila melanogaster
FBpp0075730 Q94887 Drosophila melanogaster
FBpp0076352 Q9V3A8 Drosophila melanogaster
FBpp0076237 Q9NHA8 Drosophila melanogaster
FBpp0074074 Q9VXF6 Drosophila melanogaster
FBpp0305853 L0MQ08 Drosophila melanogaster
FBpp0088271 Q9V498 Drosophila melanogaster
FBpp0074861 Q9VVR4 Drosophila melanogaster
FBpp0085887 A1ZBB1 Drosophila melanogaster
FBpp0077167 P33450 Drosophila melanogaster
FBpp0070262 Q9V3N9 Drosophila melanogaster
FBpp0081581 P29413 Drosophila melanogaster
FBpp0077760 Q9VPI6 Drosophila melanogaster
FBpp0084803 Q9VAL7 Drosophila melanogaster
FBpp0073467 Q9I7S9 Drosophila melanogaster
FBpp0077683 Q9VPU6 Drosophila melanogaster
FBpp0083961 Q9VCC2 Drosophila melanogaster
FBpp0071475 Q24298 Drosophila melanogaster