modENCODE |  Help |  blog

Protein Domain : IPR000626

Name  Ubiquitin-like Short Name  Ubiquitin-like
Type  Domain Description  Ubiquitin is a protein of 76 amino acid residues, found in all eukaryotic cells and whose sequence is extremely well conserved from protozoan to vertebrates. Ubiquitin acts through its post-translational attachment (ubiquitinylation) to other proteins, where these modifications alter the function, location or trafficking of the protein, or targets it for destruction by the 26S proteasome [].Ubiquitin is a globular protein, the last four C-terminal residues (Leu-Arg-Gly-Gly) extending from the compact structure to form a 'tail', important for its function. The latter is mediated by the covalent conjugation of ubiquitin to target proteins, by an isopeptide linkage between the C-terminal glycine and the epsilon amino group of lysine residues in the target proteins.This entry represents a domain characteristic of ubiquitin (Ub) and ubiquitin-like (Ubl) proteins such as SUMO [, ]and Nedd8 [].

Publication Counts Displayer

1 Child Features

DB identifier Name Short Name Type
IPR022617 Rad60/SUMO-like domain Rad60/SUMO_like Domain

1 Contains

DB identifier Name Short Name Type
IPR019954 Ubiquitin conserved site Ubiquitin_CS Conserved_site

4 Cross References

Identifier
Source . Name

Subject . Primary Identifier
PF00240 PFAM IPR000626
PF14560 PFAM IPR000626
PS50053 PROFILE IPR000626
SM00213 SMART IPR000626

3 Data Sets

Name URL
Swiss-Prot data set http://ca.expasy.org/sprot
InterPro data set  
InterPro GO Annotation data set  

4 Found In

DB identifier Name Short Name Type
IPR017093 Molecular chaperone regulator BAG-1 Molecular_chp_reg_BAG_1 Family
IPR015496 Ubiquilin Ubiquilin Family
IPR003977 E3 ubiquitin-protein ligase parkin Parkin Family
IPR004806 UV excision repair protein Rad23 Rad23 Family

1 GO Annotation


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Ubiquitin-like   GO:0005515 protein binding

1 Ontology Annotations


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Ubiquitin-like   GO:0005515 protein binding

1 Parent Features

DB identifier Name Short Name Type
IPR029071 Ubiquitin-related domain Ubiquitin-rel_dom Domain

335 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0073619 Q9VYD4 Drosophila melanogaster
FBpp0099676 Q9VEC8 Drosophila melanogaster
FBpp0078436 Q9VNB2 Drosophila melanogaster
FBpp0087458 Q7K549 Drosophila melanogaster
FBpp0085690 A1ZBM2 Drosophila melanogaster
FBpp0073035 P0CG69 Drosophila melanogaster
FBpp0293357 Q6IG51 Drosophila melanogaster
FBpp0083740 Q9XZ16 Drosophila melanogaster
FBpp0079606 P15357 Drosophila melanogaster
FBpp0078563 Q8IPM2 Drosophila melanogaster
FBpp0074519 Q9VWD9 Drosophila melanogaster
FBpp0073962 Q9VXN1 Drosophila melanogaster
FBpp0071182 Q7KVT0 Drosophila melanogaster
FBpp0080733 Q9VJ33 Drosophila melanogaster
FBpp0073017 Q9VZL3 Drosophila melanogaster
FBpp0305700 R9PY16 Drosophila melanogaster
FBpp0088191 Q9V3W9 Drosophila melanogaster
FBpp0077974 Q7KTX7 Drosophila melanogaster
FBpp0076505 Q9VS82 Drosophila melanogaster
FBpp0076506 Q9VS83 Drosophila melanogaster
FBpp0082817 Q9VEP9 Drosophila melanogaster
FBpp0071186 Q8IRN3 Drosophila melanogaster
FBpp0083354 O44226 Drosophila melanogaster
FBpp0083927 Q9VCD5 Drosophila melanogaster
FBpp0077159 P18101 Drosophila melanogaster
FBpp0071432 Q8SXD4 Drosophila melanogaster
FBpp0077464 Q8IPY5 Drosophila melanogaster
FBpp0079650 Q9VKZ8 Drosophila melanogaster
FBpp0078984 O97102 Drosophila melanogaster
FBpp0085529 Q9V998 Drosophila melanogaster