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Protein : FBpp0089226 D. melanogaster

Primary Accession  ? P25455 Organism . Name  Drosophila melanogaster
MD5 Checksum  3017fcba22e93e1e76873d3eea83261b UniProt Accession  P25455
UniProt Name  PIP1_DROME GenBank Identifier  AAS64631
Is UniProt Canonical  true Is Fragment  false
Length  1318 Molecular Weight  146391
Name  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase classes I and II Secondary Identifier  FBpp0089226

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1 Genes

DB identifier Secondary Identifier Symbol Name Source Organism
FBgn0004611 CG4574 Plc21C Phospholipase C at 21C FlyBase D. melanogaster


Protein --> Gene + chromosomal location and length of the gene.


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0 Components

7 Cross References

Source . Name

Subject . Primary Identifier
NP_995604.2 RefSeq FBpp0089226
NP_995606.1 RefSeq FBpp0089226
Dm.4674 UniGene FBpp0089226
NP_476851.2 RefSeq FBpp0089226
NP_476852.1 RefSeq FBpp0089226
NP_001259818.1 RefSeq FBpp0089226
NP_995605.1 RefSeq FBpp0089226

3 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set
Reactome data set  

1 Ec Numbers

Identifier Description  

1 Locations

Located On . Primary Identifier
Start End Strand
2L 318028 345445 1

48 Pathways

Identifier Name
141607 Phospholipid metabolism
129378 Synthesis of PIPs at the plasma membrane
147558 PI Metabolism
112201 Metabolism
85514 GPCR downstream signaling
78862 G alpha (q) signalling events
133868 Gastrin-CREB signalling pathway via PKC and MAPK
32504 Opioid Signalling
99045 G-protein mediated events
30626 PLC beta mediated events
81368 Signaling by GPCR
154544 Synthesis of IP3 and IP4 in the cytosol
154100 Inositol phosphate metabolism
106721 Metabolism of lipids and lipoproteins
105951 Immune System
103669 Adaptive Immune System
120473 Downstream Signaling Events Of B Cell Receptor (BCR)
120569 B Cell Activation
88681 Innate Immune System
92318 Hemostasis
88667 Platelet activation, signaling and aggregation
136059 Signal amplification
167642 Role of LAT2/NTAL/LAB on calcium mobilization
149356 DAP12 interactions
166867 Fc epsilon receptor (FCERI) signaling
150048 DAP12 signaling
149824 PI3K/AKT Signaling in Cancer
118381 Disease
118487 Signaling by EGFR in Cancer
128167 Signaling by FGFR in disease

10 Protein Domains

DB identifier Name Short Name Type
IPR000008 C2 domain C2_dom Domain
IPR011993 Pleckstrin homology-like domain PH_like_dom Domain
IPR011992 EF-hand domain pair EF-hand-dom_pair Domain
IPR001192 Phosphoinositide phospholipase C family PI-PLC_fam Family
IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain PLC-like_Pdiesterase_TIM-brl Domain
IPR015359 Phospholipase C, phosphoinositol-specific, EF-hand-like PLipase_C_EF-hand-like Domain
IPR000909 Phospholipase C, phosphatidylinositol-specific , X domain PLipase_C_PInositol-sp_X_dom Domain
IPR001711 Phospholipase C, phosphatidylinositol-specific, Y domain PLipase_C_Pinositol-sp_Y Domain
IPR014815 PLC-beta, C-terminal PLC-beta_C Domain
IPR028407 Phospholipase C, Plc21C PLC21C Family

1 Transcripts

DB identifier Gene
FBtr0078050 Plc21C