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Protein : FBpp0071140 D. melanogaster

Primary Accession  ? O96660 Organism . Name  Drosophila melanogaster
MD5 Checksum  312ffdf2d81998a7b36cf28e97020d29 UniProt Accession  O96660
UniProt Name  O96660_DROME GenBank Identifier  AAF46330
Is UniProt Canonical  true Is Fragment  false
Length  486 Molecular Weight  53677
Name  Transcription factor SMAD2 Secondary Identifier  FBpp0071140

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1 Genes

DB identifier Secondary Identifier Symbol Name Source Organism
FBgn0025800 CG2262 Smox Smad on X FlyBase D. melanogaster


Protein --> Gene + chromosomal location and length of the gene.


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0 Components

2 Cross References

Source . Name

Subject . Primary Identifier
NP_511079.1 RefSeq FBpp0071140
Dm.2941 UniGene FBpp0071140

3 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set
Reactome data set  

0 Ec Numbers

2 Locations

Located On . Primary Identifier
Start End Strand
X 8033258 8034715 -1
X 8033258 8034715 -1

25 Pathways

Identifier Name
158607 Signaling by Activin
105649 Gene Expression
80335 Generic Transcription Pathway
170534 TGFBR1 KD Mutants in Cancer
172482 SMAD2/3 Phosphorylation Motif Mutants in Cancer
172279 Loss of Function of SMAD2/3 in Cancer
172115 SMAD4 MH2 Domain Mutants in Cancer
171680 Loss of Function of SMAD4 in Cancer
170515 TGFBR2 Kinase Domain Mutants in Cancer
171073 TGFBR2 MSI Frameshift Mutants in Cancer
170535 Loss of Function of TGFBR2 in Cancer
171497 SMAD2/3 MH2 Domain Mutants in Cancer
172034 TGFBR1 LBD Mutants in Cancer
171157 Loss of Function of TGFBR1 in Cancer
113552 Developmental Biology
172402 Signaling by TGF-beta Receptor Complex in Cancer
114677 Signaling by NODAL
118381 Disease
82948 Signaling by TGF-beta Receptor Complex
140522 TGF-beta receptor signaling activates SMADs
138555 Downregulation of TGF-beta receptor signaling
134604 Downregulation of SMAD2/3:SMAD4 transcriptional activity
139570 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
129470 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
97910 Signaling Pathways

6 Protein Domains

DB identifier Name Short Name Type
IPR013790 Dwarfin Dwarfin Family
IPR003619 MAD homology 1, Dwarfin-type MAD_homology1_Dwarfin-type Domain
IPR013019 MAD homology, MH1 MAD_homology_MH1 Domain
IPR017855 SMAD domain-like SMAD_dom-like Domain
IPR001132 SMAD domain, Dwarfin-type SMAD_dom_Dwarfin-type Domain
IPR008984 SMAD/FHA domain SMAD_FHA_domain Domain

2 Transcripts

DB identifier Gene
FBtr0340159 Smox
FBtr0071192 Smox