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Gene : Ire1 D. melanogaster

DB identifier  ? FBgn0261984 Secondary Identifier  ? CG4583
Name  ? Inositol-requiring enzyme-1 Source  FlyBase
  • synonyms:
  • Ire-1,
  • FBan0004583,
  • FBgn0041204,
  • Ire,
  • dIRE1,
  • FBgn0261984,
  • dire-1,
  • Inositol required 1,
  • inositol-requiring enzyme-1,
  • FBgn0038736,
  • IRE-like,
  • IRE1,
  • CG4583

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7 Alleles

DB identifier Symbol Allele Class Organism
FBal0266575 Ire1[HMS03003]   Drosophila melanogaster
FBal0262620 Ire1[GL00141]   Drosophila melanogaster
FBal0227202 Ire1[NP5472]   Drosophila melanogaster
FBal0209742 Ire1[GD3071]   Drosophila melanogaster
FBal0159138 Ire1[f02170]   Drosophila melanogaster
FBal0227204 Ire1[e03681]   Drosophila melanogaster
FBal0227203 Ire1[e02281]   Drosophila melanogaster

14 Clones

Secondary Identifier DB identifier
EK296141 FBcl0055456
EK254422 FBcl0055462
EK135708 FBcl0055478
EK174810 FBcl0058884
EC053542 FBcl0300055
EC056199 FBcl0300056
CK01.9C.E5 FBcl0470745
IP02909 FBcl0319222
Dmel_neb_003801_0685_0695 FBcl0369780
RP003516557 FBcl0515612
RP004429202 FBcl0516968
273719 FBcl0470738
149243 FBcl0470749
193164 FBcl0470758

7 Exons

DB identifier Symbol
FBgn0261984:7 Ire1:7
FBgn0261984:6 Ire1:6
FBgn0261984:5 Ire1:5
FBgn0261984:4 Ire1:4
FBgn0261984:3 Ire1:3
FBgn0261984:2 Ire1:2
FBgn0261984:1 Ire1:1

1 Transcripts

DB identifier Gene
FBtr0113248 Ire1

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0113248-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0113248-3-prime-utr Drosophila melanogaster

Interactions

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
42358 NCBI Entrez Gene identifiers FBgn0261984
67348 BioGRID FBgn0261984

9 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  

0 Expression Scores

6 Introns

DB identifier
Organism . Name
intron_FBgn0261984:7_FBgn0261984:6 Drosophila melanogaster
intron_FBgn0261984:6_FBgn0261984:5 Drosophila melanogaster
intron_FBgn0261984:5_FBgn0261984:4 Drosophila melanogaster
intron_FBgn0261984:4_FBgn0261984:3 Drosophila melanogaster
intron_FBgn0261984:3_FBgn0261984:2 Drosophila melanogaster
intron_FBgn0261984:2_FBgn0261984:1 Drosophila melanogaster

30 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Ire1 none 4.654413548   19067489
Lipid storage Ire1 none -1.998570326   19067489
Cell cycle regulation (1) Ire1 none np   15616552
Cell cycle regulation (2) Ire1 none np   15616552
Cell size and cell-cycle regulation (1) Ire1 none sp   16496002
Brucella melitensis infection Ire1 Decreased Brucella melitensis infection 55.44   18654626
DFoxO signaling Ire1 Decreased dFoxO reporter activity 0.08   18815370
Combinatorial effect with methyl methanesulphonate (1) Ire1 none sp   19543366
Combinatorial effect with methyl methanesulphonate (2) Ire1 none sp   19543366
Muscle morphogenesis and function (1) Ire1 none np   20220848
Heat nociception (1) Ire1 none -0.2   21074052
Heat nociception (1) Ire1 none 0.38   21074052
Heart development and function (1) Ire1 none 1   20371351
Serratia marcescens infection (1) Ire1 none -0.322222222222222   19520911
Serratia marcescens infection (1) Ire1 none 0.134020618556701   19520911
Notch pathway regulation (4) Ire1 none 0   19363474
Notch pathway regulation (4) Ire1 none 0   19363474
Adiposity regulation (1) Ire1 Decreased triglyceride expression -0.411   20074523
Adiposity regulation (2) Ire1 none 0.051   20074523
Adiposity regulation (3) Ire1 Decreased triglyceride expression -1   20074523
Adiposity regulation (4) Ire1 none -0.16   20074523
Adiposity regulation (5) Ire1 Increased triglyceride expression 0.347   20074523
Actin organization and cell morphology (1) Ire1 none np   19265526
Actin organization and cell morphology (2) Ire1 none np   19265526
Actin organization and cell morphology (3) Ire1 none np   19265526
Actin organization and cell morphology (4) Ire1 none np   19265526
Actin organization and cell morphology (5) Ire1 none np   19265526
Actin organization and cell morphology (6) Ire1 none np   19265526
Vaccinia virus infection Ire1 none sp   20585561
Hippo pathway regulation Ire1 Downregulation of Hippo pathway 3.96   23263283

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