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Protein : FBpp0076098 D. melanogaster

Primary Accession  ? Q9VT57 Organism . Name  Drosophila melanogaster
MD5 Checksum  1d02f1db944a4501baf8607261a94e14 UniProt Accession  Q9VT57
UniProt Name  CDK8_DROME GenBank Identifier  AAF50197
Is UniProt Canonical  true Is Fragment  false
Length  454 Molecular Weight  53682
Name  Cyclin-dependent kinase 8 Secondary Identifier  FBpp0076098

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Genomics

1 Genes

DB identifier Secondary Identifier Symbol Name Source Organism
FBgn0015618 CG10572 Cdk8 Cyclin-dependent kinase 8 FlyBase D. melanogaster

Proteins

Protein --> Gene + chromosomal location and length of the gene.

Interactions

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Other

0 Components

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
Dm.5731 UniGene FBpp0076098
NP_536735.2 RefSeq FBpp0076098

3 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Reactome data set  

2 Ec Numbers

Identifier Description
2.7.11.22  
2.7.11.23  

1 Locations


Located On . Primary Identifier
Start End Strand
3L 9830282 9831705 -1

35 Pathways

Identifier Name
158607 Signaling by Activin
105649 Gene Expression
80335 Generic Transcription Pathway
170534 TGFBR1 KD Mutants in Cancer
172482 SMAD2/3 Phosphorylation Motif Mutants in Cancer
172279 Loss of Function of SMAD2/3 in Cancer
172115 SMAD4 MH2 Domain Mutants in Cancer
171680 Loss of Function of SMAD4 in Cancer
170515 TGFBR2 Kinase Domain Mutants in Cancer
171073 TGFBR2 MSI Frameshift Mutants in Cancer
170535 Loss of Function of TGFBR2 in Cancer
171497 SMAD2/3 MH2 Domain Mutants in Cancer
172034 TGFBR1 LBD Mutants in Cancer
171157 Loss of Function of TGFBR1 in Cancer
113552 Developmental Biology
162718 Signaling by NOTCH1 HD Domain Mutants in Cancer
162388 Signaling by NOTCH1 PEST Domain Mutants in Cancer
163048 Constitutive Signaling by NOTCH1 PEST Domain Mutants
162365 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer
162987 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
162349 FBXW7 Mutants and NOTCH1 in Cancer
162508 Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant
172402 Signaling by TGF-beta Receptor Complex in Cancer
114677 Signaling by NODAL
84551 Transcriptional Regulation of White Adipocyte Differentiation
162622 Signaling by NOTCH1 in Cancer
118381 Disease
82948 Signaling by TGF-beta Receptor Complex
140522 TGF-beta receptor signaling activates SMADs
120634 NOTCH1 Intracellular Domain Regulates Transcription

5 Protein Domains

DB identifier Name Short Name Type
IPR011009 Protein kinase-like domain Kinase-like_dom Domain
IPR000719 Protein kinase domain Prot_kinase_dom Domain
IPR017441 Protein kinase, ATP binding site Protein_kinase_ATP_BS Binding_site
IPR002290 Serine/threonine- /dual specificity protein kinase, catalytic domain Ser/Thr_dual-sp_kinase_dom Domain
IPR008271 Serine/threonine-protein kinase, active site Ser/Thr_kinase_AS Active_site

1 Transcripts

DB identifier Gene
FBtr0076369 Cdk8