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Protein : FBpp0112426 D. melanogaster

Primary Accession  ? P40417 Organism . Name  Drosophila melanogaster
MD5 Checksum  859eb0caeb97a1d8393e9bd996596f02 UniProt Accession  P40417
UniProt Name  ERKA_DROME GenBank Identifier  EAA46311
Is UniProt Canonical  true Is Fragment  false
Length  376 Molecular Weight  43151
Name  Mitogen-activated protein kinase ERK-A Secondary Identifier  FBpp0112426

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1 Genes

DB identifier Secondary Identifier Symbol Name Source Organism
FBgn0003256 CG12559 rl rolled FlyBase D. melanogaster


Protein --> Gene + chromosomal location and length of the gene.


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0 Components

6 Cross References

Source . Name

Subject . Primary Identifier
NP_001015121.3 RefSeq FBpp0112426
NP_001104348.2 RefSeq FBpp0112426
NP_001015123.1 RefSeq FBpp0112426
Dm.20303 UniGene FBpp0112426
NP_001015122.1 RefSeq FBpp0112426
NP_001104349.1 RefSeq FBpp0112426

3 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set
Reactome data set  

1 Ec Numbers

Identifier Description  

3 Locations

Located On . Primary Identifier
Start End Strand
2RHet 198996 247461 1
2RHet 198996 247461 1
2RHet 198996 247461 1

115 Pathways

Identifier Name
172443 Oncogene Induced Senescence
171890 Cellular Senescence
170887 Oxidative Stress Induced Senescence
172083 Senescence-Associated Secretory Phenotype (SASP)
144067 Cellular responses to stress
156104 IRS-related events triggered by IGF1R
152954 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
154241 IGF1R signaling cascade
159673 SHC-related events triggered by IGF1R
172469 Signaling by Leptin
133868 Gastrin-CREB signalling pathway via PKC and MAPK
81368 Signaling by GPCR
105951 Immune System
88681 Innate Immune System
6307 DINR-mediated activation
6202 Insulin signaling pathway
6313 Insulin receptor mediated signaling
34578 TRAF6 Mediated Induction of proinflammatory cytokines
110257 Activation of the AP-1 family of transcription factors
78994 MAPK targets/ Nuclear events mediated by MAP kinases
82500 MAP kinase activation in TLR cascade
114496 Axon guidance
113552 Developmental Biology
78289 NCAM signaling for neurite out-growth
94201 Signal transduction by L1
84142 Recycling pathway of L1
89546 L1CAM interactions
112455 Mitotic M-M/G1 phases
167327 FCERI mediated MAPK activation
112247 Cytokine Signaling in Immune system

7 Protein Domains

DB identifier Name Short Name Type
IPR011009 Protein kinase-like domain Kinase-like_dom Domain
IPR000719 Protein kinase domain Prot_kinase_dom Domain
IPR017441 Protein kinase, ATP binding site Protein_kinase_ATP_BS Binding_site
IPR002290 Serine/threonine- /dual specificity protein kinase, catalytic domain Ser/Thr_dual-sp_kinase_dom Domain
IPR008271 Serine/threonine-protein kinase, active site Ser/Thr_kinase_AS Active_site
IPR003527 Mitogen-activated protein (MAP) kinase, conserved site MAP_kinase_CS Conserved_site
IPR008349 Mitogen-activated protein (MAP) kinase, ERK1/2 MAPK_ERK1/2 Family

3 Transcripts

DB identifier Gene
FBtr0113703 rl
FBtr0113700 rl
FBtr0113702 rl