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Gene : E(spl)m3-HLH D. melanogaster
DB identifier  ? FBgn0002609 Secondary Identifier  ? CG8346
Name  ? Enhancer of split m3, helix-loop-helix Source  FlyBase
  • synonyms:
  • E(spl)C,
  • E(spl) region transcript m3,
  • FBan0008346,
  • FBgn0002609,
  • split locus enhancer protein m3,
  • HLH-m3,
  • E(Spl)-HLH-m3,
  • E(spl)C m3,
  • CG8346,
  • FBgn0010046,
  • m3,
  • E(spl)-m3,
  • E(spl)M3,
  • Enhancer of split m3,
  • HLHM3,
  • bHLHc14
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This Gene is in one list:
Fly classII (760)

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9 Alleles

DB identifier Symbol Allele Class Organism
FBal0183325 E(spl)m3-HLH[Act5C.PG]   Drosophila melanogaster
FBal0194920 E(spl)m3-HLH[dsRNA.cDa]   Drosophila melanogaster
FBal0033741 E(spl)m3-HLH[+t7.2]   Drosophila melanogaster
FBal0194921 E(spl)m3-HLH[dsRNA.cDb]   Drosophila melanogaster
FBal0223049 E(spl)m3-HLH[d05262]   Drosophila melanogaster
FBal0093289 E(spl)m3-HLH[Scer\UAS.cLa]   Drosophila melanogaster
FBal0275961 E(spl)m3-HLH[NIG.8346R]   Drosophila melanogaster
FBal0219983 E(spl)m3-HLH[JF01999]   Drosophila melanogaster
FBal0183324 E(spl)m3-HLH[d01076]   Drosophila melanogaster

51 Clones

Secondary Identifier DB identifier
DPiM_RE19116 FBcl0742022
EK087510 FBcl0001616
EK092261 FBcl0002298
EK218714 FBcl0002794
EK075759 FBcl0002812
EK092159 FBcl0002830
EK240029 FBcl0002976
EK242229 FBcl0003052
EK119134 FBcl0003090
EK082059 FBcl0003150
RE08505 FBcl0230731
RE19116 FBcl0230737
CK01.5B.E4 FBcl0407659
CK01.144C.A4 FBcl0394931
CK01.104B.C11 FBcl0406948
CK01.6A.F10 FBcl0407338
CK01.108A.H10 FBcl0407458
273882 FBcl0407529
CK01.113B.G3 FBcl0407615
CK01.97D.G6 FBcl0407631
CK01.108A.G6 FBcl0407647
RP003559592 FBcl0565786
RP003513474 FBcl0565787
RP003402371 FBcl0565788
RP003510608 FBcl0565789
RP003455548 FBcl0565790
RP003038634 FBcl0565791
RP003549066 FBcl0565792
RP003484095 FBcl0565793
RP003501432 FBcl0565794

1 Exons

DB identifier Symbol
FBgn0002609:1 E(spl)m3-HLH:1

1 Transcripts

DB identifier Gene
FBtr0084958 E(spl)m3-HLH

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0084958-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0084958-3-prime-utr Drosophila melanogaster

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0 Pathways

2 Cross References

Identifier
Source . Name
Subject . Primary Identifier
43156 NCBI Entrez Gene identifiers FBgn0002609
68056 BioGRID FBgn0002609

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier
Submission . Title
Cell Line . Name
Developmental Stage . Name 		Score
FBgn0002609 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 23.0
FBgn0002609 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 48.0
FBgn0002609 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 80.0
FBgn0002609 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 37.0
FBgn0002609 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 80.0
FBgn0002609 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 0.0
FBgn0002609 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 40.0
FBgn0002609 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 65.0
FBgn0002609 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 41.0
FBgn0002609 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 42.0
FBgn0002609 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 26.0
FBgn0002609 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 59.0
FBgn0002609 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 0.0
FBgn0002609 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 22.0
FBgn0002609 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 0.0
FBgn0002609 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 20.0
FBgn0002609 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 84.0
FBgn0002609 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 0.0
FBgn0002609 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 157.0
FBgn0002609 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 45.0
FBgn0002609 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 59.0
FBgn0002609 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 49.0
FBgn0002609 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 9.0
FBgn0002609 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 19.0
FBgn0002609 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 0.0
FBgn0002609 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 0.0
FBgn0002609 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 0.0
FBgn0002609 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 77.0
FBgn0002609 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 382.0
FBgn0002609 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1017.0

0 Introns

13 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage E(spl)m3-HLH none 0.645469107   19067489
Lipid storage E(spl)m3-HLH none 1.132237584   19067489
Lipid storage E(spl)m3-HLH none 0.712795014   19067489
Lipid storage E(spl)m3-HLH none 1.592180765   19067489
Constitutive protein secretion and Golgi organization (1) E(spl)m3-HLH Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) E(spl)m3-HLH none sp   16496002
RNAi pathway E(spl)m3-HLH Decreased RNAi effect 6   16882716
Dendrite pattern formation E(spl)m3-HLH none np   16547170
Mutant human huntingtin aggregation E(spl)m3-HLH Decreased mutant human huntingtin aggregation <= -2   19789644
PGN-induced dJNK phosphorylation E(spl)m3-HLH Increased P-JNK protein expression with PGN 5.37 15 min PGN induction 19893628
PGN-induced dJNK phosphorylation E(spl)m3-HLH Increased P-JNK protein expression with PGN 2.54 60 min PGN induction 19893628
Hippo pathway regulation E(spl)m3-HLH none -0.24   23263283
Glycosylation regulation (1) E(spl)m3-HLH none sp   21203496

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