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Gene : Shc D. melanogaster

DB identifier  ? FBgn0015296 Secondary Identifier  ? CG3715
Name  ? SHC-adaptor protein Source  FlyBase
  • synonyms:
  • FBgn0015296,
  • DSHC,
  • FBan0003715,
  • CG3715,
  • shc,
  • FBgn0035990,
  • D-Shc

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9 Alleles

DB identifier Symbol Allele Class Organism
FBal0134152 Shc[KG06847]   Drosophila melanogaster
FBal0147419 Shc[+tEa]   Drosophila melanogaster
FBal0181550 Shc[13G]   Drosophila melanogaster
FBal0141419 Shc[SL20]   Drosophila melanogaster
FBal0105104 Shc[BG]   Drosophila melanogaster
FBal0105105 Shc[111-40] amorphic allele - genetic evidence Drosophila melanogaster
FBal0208530 Shc[GD11053]   Drosophila melanogaster
FBal0230798 Shc[KK100514]   Drosophila melanogaster
FBal0273927 Shc[NIG.3715R]   Drosophila melanogaster

35 Clones

Secondary Identifier DB identifier
DPiM_FI07258 FBcl0741711
bs41d05 FBcl0049617
EN06148 FBcl0093793
EN06761 FBcl0093851
EK094229 FBcl0094014
EK200824 FBcl0095372
EK098831 FBcl0095838
EK304955 FBcl0101774
EK242560 FBcl0103158
EK268747 FBcl0103164
EK268516 FBcl0103166
GH28729 FBcl0117323
LD07456 FBcl0156183
LP07907 FBcl0184750
LP03551 FBcl0184818
LP04045 FBcl0184823
LP03826 FBcl0184825
RH57813 FBcl0254930
SD05206 FBcl0280299
SD07782 FBcl0280308
SD16566 FBcl0280373
SD11269 FBcl0289509
GM23744 FBcl0354717
FI07258 FBcl0475020
524912 FBcl0479194
CK01.109B.H5 FBcl0479171
CK01.123D.H1 FBcl0479177
525601 FBcl0479200
RP004464092 FBcl0672174
RP004204266 FBcl0672175

2 Exons

DB identifier Symbol
FBgn0015296:1 Shc:1
FBgn0015296:2 Shc:2

1 Transcripts

DB identifier Gene
FBtr0076458 Shc

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0076458-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0076458-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
44052 NCBI Entrez Gene identifiers FBgn0015296
68802 BioGRID FBgn0015296

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0015296 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1009.0
FBgn0015296 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 710.0
FBgn0015296 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 512.0
FBgn0015296 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 912.0
FBgn0015296 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1082.0
FBgn0015296 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 472.0
FBgn0015296 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 1231.0
FBgn0015296 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 994.0
FBgn0015296 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 805.0
FBgn0015296 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 865.0
FBgn0015296 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1430.0
FBgn0015296 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 625.0
FBgn0015296 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 785.0
FBgn0015296 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 842.0
FBgn0015296 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 878.0
FBgn0015296 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 739.0
FBgn0015296 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 909.0
FBgn0015296 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 663.0
FBgn0015296 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 993.0
FBgn0015296 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 839.0
FBgn0015296 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 891.0
FBgn0015296 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 574.0
FBgn0015296 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 774.0
FBgn0015296 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1349.0
FBgn0015296 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 601.0
FBgn0015296 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 913.0
FBgn0015296 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 417.0
FBgn0015296 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 761.0
FBgn0015296 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 563.0
FBgn0015296 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 644.0

1 Introns

DB identifier
Organism . Name
intron_FBgn0015296:1_FBgn0015296:2 Drosophila melanogaster

19 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Shc none -0.004043838   19067489
Lipid storage Shc none 0.488906008   19067489
Heat nociception (1) Shc none -1.17   21074052
Heart development and function (1) Shc none 1   20371351
Serratia marcescens infection (1) Shc none 0.577319587628865   19520911
Serratia marcescens infection (1) Shc none 0.705882352941176   19520911
Serratia marcescens infection (1) Shc none 1.26136363636363   19520911
Notch pathway regulation (4) Shc none 0   19363474
Notch induced transcription Shc none 2.0052 without Notch stimulation 20959007
Notch induced transcription Shc Upregulation of Notch pathway after Notch stimulation 4.3372 N(delta)ecn Notch stimulation 20959007
Notch induced transcription Shc none 0.52018 N(delta)ecn Notch stimulation 20959007
Adiposity regulation (1) Shc none -0.285   20074523
Adiposity regulation (1) Shc none 0.202   20074523
RTK-Ras-ERK pathway regulation (1) Shc Decreased ERK phosphorylation after EGF stimulation -1.61 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) Shc none -0.25 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Shc none -1.48 30 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Shc none -1.14 10 minutes sSpitz stimulation 22028469
Hippo pathway regulation Shc none 1.05   23263283
Glycosylation regulation (1) Shc none sp   21203496

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