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Gene : Dredd D. melanogaster

DB identifier  ? FBgn0020381 Secondary Identifier  ? CG7486
Name  ? Death related ced-3/Nedd2-like protein Source  FlyBase
  • synonyms:
  • FBgn0013388,
  • FBgn0020381,
  • FBtr0070152,
  • Dedd,
  • CG7486,
  • Death caspase-2,
  • DCP2,
  • Drosophila caspase,
  • unnamed,
  • dDredd,
  • Ced-3-like/Nedd2-like protein,
  • anon-1BCa,
  • death-related ced-3/neural precursor cell expressed developmentally downregulated 2 (NEDD2)-like protein,
  • caspase,
  • FBtr0070154,
  • Redd,
  • FBpp0070148,
  • EG:115C2.9,
  • FBgn0023366,
  • DCP-2,
  • FBan0007486,
  • DREDD,
  • FBgn0024454,
  • FBpp0070147,
  • FBtr0070153,
  • DCP-2/DREDD,
  • CASP8_DROME,
  • FBpp0070149,
  • Dredd/DCP-2

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34 Alleles

DB identifier Symbol Allele Class Organism
FBal0160598 Dredd[EY08404]   Drosophila melanogaster
FBal0117838 Dredd[EP1412] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0269195 Dredd[Scer\UAS.cKa]   Drosophila melanogaster
FBal0267203 Dredd[1]   Drosophila melanogaster
FBal0244090 Dredd[dsRNA.Scer\UAS.cLa]   Drosophila melanogaster
FBal0093433 Dredd[alpha.MtnA]   Drosophila melanogaster
FBal0093424 Dredd[+tCa]   Drosophila melanogaster
FBal0120961 Dredd[L23] amorphic allele - genetic evidence Drosophila melanogaster
FBal0122284 Dredd[unspecified]   Drosophila melanogaster
FBal0120964 Dredd[D44] amorphic allele - genetic evidence Drosophila melanogaster
FBal0093426 Dredd[gamma.MtnA]   Drosophila melanogaster
FBal0120962 Dredd[F64] amorphic allele - genetic evidence Drosophila melanogaster
FBal0156692 Dredd[dsRNA.cPa]   Drosophila melanogaster
FBal0120965 Dredd[D3]   Drosophila melanogaster
FBal0120966 Dredd[B118] amorphic allele - genetic evidence Drosophila melanogaster
FBal0093431 Dredd[beta.MtnA]   Drosophila melanogaster
FBal0148068 Dredd[dsRNA.cMa]   Drosophila melanogaster
FBal0120963 Dredd[D55] amorphic allele - genetic evidence Drosophila melanogaster
FBal0122285 Dredd[hs.PH]   Drosophila melanogaster
FBal0263083 Dredd[HMS00063]   Drosophila melanogaster
FBal0093436 Dredd[alpha.Delta1-120.MtnA.T:Zzzz\FLAG,T:Hsap\MYC]   Drosophila melanogaster
FBal0093434 Dredd[alpha.MtnA.T:Zzzz\FLAG,T:Hsap\MYC]   Drosophila melanogaster
FBal0093430 Dredd[delta.MtnA.T:Hsap\MYC]   Drosophila melanogaster
FBal0093429 Dredd[delta.MtnA.T:Uuuu\T7,T:Zzzz\His6]   Drosophila melanogaster
FBal0093427 Dredd[gamma.MtnA.T:Uuuu\T7,T:Zzzz\His6]   Drosophila melanogaster
FBal0128226 Dredd[Act5C.T:SV5\V5]   Drosophila melanogaster
FBal0101733 Dredd[C:A.MtnA.T:Hsap\MYC]   Drosophila melanogaster
FBal0101732 Dredd[MtnA.T:Hsap\MYC]   Drosophila melanogaster
FBal0126624 Dredd[Scer\UAS.cVa]   Drosophila melanogaster
FBal0189936 Dredd[Scer\UAS.T:Ivir\HA1]   Drosophila melanogaster

14 Clones

Secondary Identifier DB identifier
EK184030 FBcl0019490
EK155746 FBcl0020662
GH10971 FBcl0127181
GH08960 FBcl0127193
GH25343 FBcl0127195
LP05556 FBcl0188118
EC052060 FBcl0298365
EC051574 FBcl0298366
EC051575 FBcl0298367
EC055115 FBcl0298368
EC056599 FBcl0298369
CK01.14B.G11 FBcl0405755
37550 FBcl0405464
55990 FBcl0405570

8 Exons

DB identifier Symbol
FBgn0020381:8 Dredd:8
FBgn0020381:7 Dredd:7
FBgn0020381:3 Dredd:3
FBgn0020381:2 Dredd:2
FBgn0020381:1 Dredd:1
FBgn0020381:5 Dredd:5
FBgn0020381:4 Dredd:4
FBgn0020381:6 Dredd:6

4 Transcripts

DB identifier Gene
FBtr0114561 Dredd
FBtr0114560 Dredd
FBtr0340083 Dredd
FBtr0114559 Dredd

8 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0114559-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0114560-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0114561-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0340083-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0114559-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0114560-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0114561-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0340083-3-prime-utr Drosophila melanogaster

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Other

0 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
31011 NCBI Entrez Gene identifiers FBgn0020381
57579 BioGRID FBgn0020381

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from UniProt  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0020381 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 385.0
FBgn0020381 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 327.0
FBgn0020381 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 327.0
FBgn0020381 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 414.0
FBgn0020381 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 324.0
FBgn0020381 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 223.0
FBgn0020381 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 325.0
FBgn0020381 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 172.0
FBgn0020381 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 279.0
FBgn0020381 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 478.0
FBgn0020381 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 463.0
FBgn0020381 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 203.0
FBgn0020381 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 467.0
FBgn0020381 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 298.0
FBgn0020381 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 405.0
FBgn0020381 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 337.0
FBgn0020381 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 544.0
FBgn0020381 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 180.0
FBgn0020381 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 581.0
FBgn0020381 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 210.0
FBgn0020381 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 519.0
FBgn0020381 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 104.0
FBgn0020381 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 469.0
FBgn0020381 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 441.0
FBgn0020381 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 399.0
FBgn0020381 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 186.0
FBgn0020381 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 120.0
FBgn0020381 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 71.0
FBgn0020381 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 135.0
FBgn0020381 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 151.0

10 Introns

DB identifier
Organism . Name
intron_FBgn0020381:8_FBgn0020381:7 Drosophila melanogaster
intron_FBgn0020381:7_FBgn0020381:3 Drosophila melanogaster
intron_FBgn0020381:3_FBgn0020381:2 Drosophila melanogaster
intron_FBgn0020381:2_FBgn0020381:1 Drosophila melanogaster
intron_FBgn0020381:8_FBgn0020381:5 Drosophila melanogaster
intron_FBgn0020381:5_FBgn0020381:3 Drosophila melanogaster
intron_FBgn0020381:8_FBgn0020381:4 Drosophila melanogaster
intron_FBgn0020381:4_FBgn0020381:2 Drosophila melanogaster
intron_FBgn0020381:8_FBgn0020381:6 Drosophila melanogaster
intron_FBgn0020381:6_FBgn0020381:3 Drosophila melanogaster

21 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Dredd none 0.532851305   19067489
Lipid storage Dredd none 0   19067489
Imd pathway regulation Dredd Decreased Dipt::lacZ protein expression after lipopolysaccharide stimulation 3   15221030
Innate immunity Dredd Decreased IMD/Rel reporter activity -5   16170305
Cell size and cell-cycle regulation (1) Dredd none sp   16496002
Muscle morphogenesis and function (1) Dredd none np   20220848
Heat nociception (1) Dredd none -1.17   21074052
Heart development and function (1) Dredd none 1   20371351
Serratia marcescens infection (1) Dredd none 0.590163934426229   19520911
Notch pathway regulation (4) Dredd none 0   19363474
PGN-induced dJNK phosphorylation Dredd Decreased P-JNK protein expression with PGN -3.49 15 min PGN induction 19893628
Adiposity regulation (1) Dredd none -0.296   20074523
Blood cell homeostasis regulation (1) Dredd none np   20540764
Blood cell homeostasis regulation (2) Dredd none np   20540764
RTK-Ras-ERK pathway regulation (1) Dredd Decreased ERK phosphorylation after EGF stimulation -1.5 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) Dredd none 0.3 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Dredd none 0.55 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Dredd none 0.76 30 minutes sSpitz stimulation 22028469
Wg pathway regulation (1) Dredd Decreased WgRluc and not changed sFluc protein expression medium   21886182
Hippo pathway regulation Dredd none -0.19   23263283
Glycosylation regulation (1) Dredd none sp   21203496

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