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Gene : TSG101 D. melanogaster

DB identifier  ? FBgn0036666 Secondary Identifier  ? CG9712
Name  ? tumor suppressor protein 101 Source  FlyBase
  • synonyms:
  • burs,
  • FBan0009712,
  • FBgn0082594,
  • Ept,
  • vps23,
  • Erupted,
  • Tsg101,
  • CG9712,
  • ESCRT-I,
  • dVps23,
  • FBgn0036666,
  • DmTSG101,
  • Tumor Susceptibility Gene-101,
  • dTSg101

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12 Alleles

DB identifier Symbol Allele Class Organism
FBal0181319 TSG101[f00976]   Drosophila melanogaster
FBal0197868 TSG101[P26] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0263056 TSG101[GLV21075]   Drosophila melanogaster
FBal0278886 TSG101[HMS01768]   Drosophila melanogaster
FBal0212938 TSG101[2]   Drosophila melanogaster
FBal0212939 TSG101[hs.PM]   Drosophila melanogaster
FBal0215635 TSG101[MtnA.T:Ivir\HA1]   Drosophila melanogaster
FBal0208701 TSG101[GD14295]   Drosophila melanogaster
FBal0222574 TSG101[e00381]   Drosophila melanogaster
FBal0268623 TSG101[942]   Drosophila melanogaster
FBal0268624 TSG101[1139]   Drosophila melanogaster
FBal0276530 TSG101[NIG.9712R]   Drosophila melanogaster

62 Clones

Secondary Identifier DB identifier
ESG019d.E21_B01 FBcl0000690
AT20456 FBcl0005401
AT23186 FBcl0007489
AT18675 FBcl0011431
EK122501 FBcl0047578
EK056451 FBcl0047586
EK136958 FBcl0047638
bs04c03 FBcl0048245
EC32741 FBcl0062605
EN03064 FBcl0092133
EN01633 FBcl0092139
EN17303 FBcl0092475
GH09529 FBcl0106495
GH18254 FBcl0106509
GH22492 FBcl0106549
LD32419 FBcl0164826
LD47333 FBcl0164827
LP12350 FBcl0180657
RE37147 FBcl0197066
RE54653 FBcl0197098
RE26756 FBcl0197104
RE73608 FBcl0197115
RH29534 FBcl0244139
RH10957 FBcl0244199
RH25148 FBcl0244308
RH42447 FBcl0244310
RH36765 FBcl0244311
RH30168 FBcl0244313
RH06637 FBcl0244361
SD14244 FBcl0277533

7 Exons

DB identifier Symbol
FBgn0036666:1 TSG101:1
FBgn0036666:2 TSG101:2
FBgn0036666:3 TSG101:3
FBgn0036666:4 TSG101:4
FBgn0036666:5 TSG101:5
FBgn0036666:6 TSG101:6
FBgn0036666:7 TSG101:7

1 Transcripts

DB identifier Gene
FBtr0075329 TSG101

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0075329-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0075329-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
39881 NCBI Entrez Gene identifiers FBgn0036666
65180 BioGRID FBgn0036666

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0036666 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 3755.0
FBgn0036666 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 3398.0
FBgn0036666 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1726.0
FBgn0036666 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 2015.0
FBgn0036666 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 2721.0
FBgn0036666 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 1324.0
FBgn0036666 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 2431.0
FBgn0036666 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 1749.0
FBgn0036666 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 2272.0
FBgn0036666 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 2762.0
FBgn0036666 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 2006.0
FBgn0036666 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 1565.0
FBgn0036666 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1786.0
FBgn0036666 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 2109.0
FBgn0036666 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 2143.0
FBgn0036666 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 1824.0
FBgn0036666 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 2652.0
FBgn0036666 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1389.0
FBgn0036666 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1751.0
FBgn0036666 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1881.0
FBgn0036666 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 1726.0
FBgn0036666 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 2048.0
FBgn0036666 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 1859.0
FBgn0036666 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1832.0
FBgn0036666 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 2238.0
FBgn0036666 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 1871.0
FBgn0036666 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 1666.0
FBgn0036666 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 1077.0
FBgn0036666 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1105.0
FBgn0036666 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 895.0

6 Introns

DB identifier
Organism . Name
intron_FBgn0036666:1_FBgn0036666:2 Drosophila melanogaster
intron_FBgn0036666:2_FBgn0036666:3 Drosophila melanogaster
intron_FBgn0036666:3_FBgn0036666:4 Drosophila melanogaster
intron_FBgn0036666:4_FBgn0036666:5 Drosophila melanogaster
intron_FBgn0036666:5_FBgn0036666:6 Drosophila melanogaster
intron_FBgn0036666:6_FBgn0036666:7 Drosophila melanogaster

20 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage TSG101 none 0.360027745   19067489
Lipid storage TSG101 none 0.79057107   19067489
L. monocytogenes infection TSG101 Escape pff LLO- strain *   16157870
L. monocytogenes infection TSG101 Fewer infected cells *   16157870
Cell size and cell-cycle regulation (1) TSG101 none sp   16496002
Cell size and cell-cycle regulation (1) TSG101 none sp   16496002
M. smegmatis infection TSG101 Increased M. smegmatis infection np   18287038
CD4 regulation by human immunodeficiency virus Type 1 Nef (HIV-1 Nef) TSG101 none 3.2   17267500
Muscle morphogenesis and function (1) TSG101 Lethal np   20220848
Heart development and function (1) TSG101 none 1   20371351
Heart development and function (2) TSG101 none 2.53   20371351
Serratia marcescens infection (1) TSG101 none -0.464646464646464   19520911
Notch pathway regulation (4) TSG101 Completely lethal (pupal) sp   19363474
Notch pathway regulation (1) TSG101 Upregulation of Notch pathway np   20493818
Notch pathway regulation (2) TSG101 Downregulation of Notch pathway; adult wing margin: notches sp en-GAL4 20493818
Notch pathway regulation (2) TSG101 Upregulation of Notch pathway; delay of larval development; wing disc size: overgrown; wing disc NRE:EGFP: up, broader, ectopic; wing disc myrRFP: accumulation; lethal sp en-GAL4 20493818
Notch pathway regulation (3) TSG101 Upregulation of Notch pathway np   20493818
Hippo pathway regulation TSG101 none 0.22   23263283
Glycosylation regulation (1) TSG101 none sp   21203496
Huntingtin (Htt) aggregates formation TSG101 Decreased formation of mutant Huntingtin (Httex1-Qn) protein aggregates np   20100940

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