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Gene : Syx5 D. melanogaster

DB identifier  ? FBgn0011708 Secondary Identifier  ? CG4214
Name  ? Syntaxin 5 Source  FlyBase
  • synonyms:
  • FBgn0011708,
  • Syntaxin 5,
  • FBgn0015339,
  • syntaxin5,
  • dSyntaxin5,
  • FBgn0020602,
  • FBgn0001996,
  • anon-35Fd,
  • II,
  • FBan0004214,
  • anon-35Fb,
  • l(2)35Ff,
  • Synx5,
  • dSyx5,
  • syx5,
  • Syntaxin,
  • SED5,
  • dSed5p,
  • Syx,
  • lethal(2)35Ff,
  • CG4214,
  • Syx5A,
  • BG:DS02740.12,
  • SYN5,
  • dSed5,
  • DmSyx5

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15 Alleles

DB identifier Symbol Allele Class Organism
FBal0280611 Syx5[Scer\UAS.T:Hsap\MYC]   Drosophila melanogaster
FBal0181335 Syx5[e02643]   Drosophila melanogaster
FBal0159698 Syx5[EY07901]   Drosophila melanogaster
FBal0141353 Syx5[EP2313]   Drosophila melanogaster
FBal0159697 Syx5[t14.2]   Drosophila melanogaster
FBal0035012 Syx5[unspecified]   Drosophila melanogaster
FBal0141355 Syx5[AE48]   Drosophila melanogaster
FBal0141356 Syx5[AA73]   Drosophila melanogaster
FBal0141354 Syx5[AE73]   Drosophila melanogaster
FBal0035013 Syx5[AR113]   Drosophila melanogaster
FBal0181336 Syx5[dsRNA.cKa]   Drosophila melanogaster
FBal0208682 Syx5[GD1743]   Drosophila melanogaster
FBal0242505 Syx5[JF03330]   Drosophila melanogaster
FBal0231010 Syx5[KK100952]   Drosophila melanogaster
FBal0274146 Syx5[NIG.4214R]   Drosophila melanogaster

120 Clones

Secondary Identifier DB identifier
Dmel_neb_001066_0354_3644 FBcl0374616
Dmel_neb_008683_0341_2924 FBcl0374617
Dmel_neb_013105_0166_1891 FBcl0374618
AT09884 FBcl0040039
bs48a08 FBcl0056911
EP03652 FBcl0087939
EK050441 FBcl0100994
EK123251 FBcl0101006
EN15048 FBcl0101097
EK117905 FBcl0101792
GH22093 FBcl0122073
GM06766 FBcl0143347
LD09049 FBcl0157972
LD02623 FBcl0157973
LD29042 FBcl0172196
LD28045 FBcl0172200
LP21063 FBcl0186410
LP03569 FBcl0186413
LP08421 FBcl0186415
LP01930 FBcl0186417
LP10588 FBcl0186419
LP05355 FBcl0186420
RE26540 FBcl0218879
RE32789 FBcl0218882
RE01550 FBcl0218884
RE65878 FBcl0218885
RE65153 FBcl0218887
RE30249 FBcl0218889
RE15171 FBcl0218891
RE58892 FBcl0218901

4 Exons

DB identifier Symbol
FBgn0011708:2 Syx5:2
FBgn0011708:1 Syx5:1
FBgn0011708:3 Syx5:3
FBgn0011708:4 Syx5:4

2 Transcripts

DB identifier Gene
FBtr0080832 Syx5
FBtr0080831 Syx5

4 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0080831-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0080832-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0080831-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0080832-3-prime-utr Drosophila melanogaster

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0 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
34966 NCBI Entrez Gene identifiers FBgn0011708
60977 BioGRID FBgn0011708

10 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from UniProt  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0011708 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1341.0
FBgn0011708 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 1466.0
FBgn0011708 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 788.0
FBgn0011708 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1048.0
FBgn0011708 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1229.0
FBgn0011708 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 924.0
FBgn0011708 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 1657.0
FBgn0011708 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 1643.0
FBgn0011708 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 1016.0
FBgn0011708 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1421.0
FBgn0011708 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1166.0
FBgn0011708 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 1549.0
FBgn0011708 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1661.0
FBgn0011708 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 886.0
FBgn0011708 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 779.0
FBgn0011708 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 721.0
FBgn0011708 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1417.0
FBgn0011708 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1408.0
FBgn0011708 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1257.0
FBgn0011708 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1324.0
FBgn0011708 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 937.0
FBgn0011708 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 1575.0
FBgn0011708 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 995.0
FBgn0011708 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1922.0
FBgn0011708 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1332.0
FBgn0011708 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 2196.0
FBgn0011708 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 1224.0
FBgn0011708 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 817.0
FBgn0011708 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 729.0
FBgn0011708 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 691.0

3 Introns

DB identifier
Organism . Name
intron_FBgn0011708:1_FBgn0011708:3 Drosophila melanogaster
intron_FBgn0011708:3_FBgn0011708:4 Drosophila melanogaster
intron_FBgn0011708:2_FBgn0011708:4 Drosophila melanogaster

35 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Syx5 none -0.787661758   19067489
Lipid storage Syx5 none 1.383682949   19067489
ERK signaling Syx5 ERK activation increased strong   17086199
Cytokinesis Syx5 Multi-nucleate cells np   15380073
Cytokinesis regulation Syx5 Binucleate cells medium   15547975
Intracellular Listeria monocytogenes infection Syx5 Decreased GFP protein expression strong   16020693
L. monocytogenes infection Syx5 Fewer infected cells *   16157870
Constitutive protein secretion and Golgi organization (1) Syx5 Decreased horseradish peroxidase protein expression sp   16452979
Constitutive protein secretion and Golgi organization (2) Syx5 Fused Golgi membranes with endoplasmic reticulum np   16452979
Cell size and cell-cycle regulation (1) Syx5 none sp   16496002
Candida albicans phagocytosis (1) Syx5 Decreased Candida albicans phagocytosis np   16336044
Candida albicans phagocytosis (2) Syx5 Decreased Escherichia coli phagocytosis 18   16336044
Candida albicans phagocytosis (3) Syx5 Decreased latex beads phagocytosis 38   16336044
CD4 regulation by human immunodeficiency virus Type 1 Nef (HIV-1 Nef) Syx5 none 1.52   17267500
Brucella melitensis infection Syx5 Decreased Brucella melitensis infection 1.98   18654626
Mutant human huntingtin aggregation Syx5 Decreased mutant human huntingtin aggregation <= -2   19789644
Muscle morphogenesis and function (1) Syx5 Lethal np   20220848
Muscle morphogenesis and function (1) Syx5 Lethal np   20220848
Heat nociception (1) Syx5 none -1.17   21074052
Heart development and function (1) Syx5 none 0.67   20371351
Heart development and function (2) Syx5 Decreased viability 3.53   20371351
Serratia marcescens infection (1) Syx5 Decreased viability after Serratia marcescens infection -1.66363636363636   19520911
Serratia marcescens infection (2) Syx5 none sp   19520911
Serratia marcescens infection (6) Syx5 Larval lethality or failure to eclose np   19520911
Notch pathway regulation (4) Syx5 Completely lethal (before pupal) sp   19363474
Notch pathway regulation (4) Syx5 Completely lethal (before pupal) sp   19363474
Notch pathway regulation (1) Syx5 Downregulation of Notch pathway np   20493818
S2 cell spreading Syx5 Increased actin protein expression at cell perimeter on Con A surface sp   21041442
RTK-Ras-ERK pathway regulation (1) Syx5 Increased ERK phosphorylation after EGF stimulation 1.56 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) Syx5 Decreased ERK phosphorylation after EGF stimulation -1.56 10 minutes EGF stimulation 22028469

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