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Gene : E(Pc) D. melanogaster

DB identifier  ? FBgn0000581 Secondary Identifier  ? CG7776
Name  ? Enhancer of Polycomb Source  FlyBase
  • synonyms:
  • GH14582,
  • FBgn0000581,
  • anon-48Ac,
  • l(2)28-28-12,
  • E(PC),
  • III,
  • GH05739,
  • CG7776,
  • Enhancer of polycomb,
  • FBan0007776,
  • transcript group III,
  • FBgn0015874

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23 Alleles

DB identifier Symbol Allele Class Organism
FBal0184021 E(Pc)[d09706]   Drosophila melanogaster
FBal0131250 E(Pc)[EP608]   Drosophila melanogaster
FBal0086003 E(Pc)[2]   Drosophila melanogaster
FBal0152588 E(Pc)[D4]   Drosophila melanogaster
FBal0003311 E(Pc)[1]   Drosophila melanogaster
FBal0086872 E(Pc)[rv10]   Drosophila melanogaster
FBal0152587 E(Pc)[w3]   Drosophila melanogaster
FBal0038819 E(Pc)[unspecified] amorphic allele - genetic evidence, gain of function allele Drosophila melanogaster
FBal0086871 E(Pc)[rv4]   Drosophila melanogaster
FBal0086870 E(Pc)[rv9]   Drosophila melanogaster
FBal0262643 E(Pc)[GL00169]   Drosophila melanogaster
FBal0288738 E(Pc)[enHSP1.+75kb]   Drosophila melanogaster
FBal0288739 E(Pc)[en1.+75kb]   Drosophila melanogaster
FBal0288740 E(Pc)[en1.+75kb-2]   Drosophila melanogaster
FBal0243852 E(Pc)[NIG.7776R]   Drosophila melanogaster
FBal0239601 E(Pc)[JF03101]   Drosophila melanogaster
FBal0206917 E(Pc)[GD12282]   Drosophila melanogaster
FBal0288365 E(Pc)[en2]   Drosophila melanogaster
FBal0288366 E(Pc)[en2.DeltaPSE1]   Drosophila melanogaster
FBal0288367 E(Pc)[en2.DeltaPSE2]   Drosophila melanogaster
FBal0288368 E(Pc)[en2.DeltaPSE1-2]   Drosophila melanogaster
FBal0226274 E(Pc)[5-HA-1544]   Drosophila melanogaster
FBal0226275 E(Pc)[5-HA-1575]   Drosophila melanogaster

70 Clones

Secondary Identifier DB identifier
AT25664 FBcl0024151
AT23619 FBcl0024153
EP16318 FBcl0081915
EP16816 FBcl0081935
EK056238 FBcl0091976
EK155317 FBcl0092728
EK249851 FBcl0092782
EK068840 FBcl0092838
EK187401 FBcl0092886
EK300925 FBcl0092896
EK157157 FBcl0092954
EK187953 FBcl0092972
EK219726 FBcl0092982
EK177936 FBcl0092998
EK173530 FBcl0093006
EK247412 FBcl0093012
EK107924 FBcl0093020
EK242064 FBcl0093028
EK250802 FBcl0093082
EK054435 FBcl0093086
EK068034 FBcl0093104
EK291354 FBcl0093112
GH05739 FBcl0130895
GH14582 FBcl0133595
LP07034 FBcl0190665
CK01.84B.B8 FBcl0425388
CK01.86A.A4 FBcl0425413
IP06127 FBcl0338842
IP06227 FBcl0338843
GH07250 FBcl0338844

16 Exons

DB identifier Symbol
FBgn0000581:2 E(Pc):2
FBgn0000581:5 E(Pc):5
FBgn0000581:6 E(Pc):6
FBgn0000581:7 E(Pc):7
FBgn0000581:8 E(Pc):8
FBgn0000581:9 E(Pc):9
FBgn0000581:11 E(Pc):11
FBgn0000581:12 E(Pc):12
FBgn0000581:13 E(Pc):13
FBgn0000581:14 E(Pc):14
FBgn0000581:4 E(Pc):4
FBgn0000581:10 E(Pc):10
FBgn0000581:16 E(Pc):16
FBgn0000581:15 E(Pc):15
FBgn0000581:3 E(Pc):3
FBgn0000581:1 E(Pc):1

5 Transcripts

DB identifier Gene
FBtr0330623 E(Pc)
FBtr0330622 E(Pc)
FBtr0088139 E(Pc)
FBtr0330621 E(Pc)
FBtr0088140 E(Pc)

10 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0088139-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0088140-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0330621-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0330622-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0330623-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0088139-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0088140-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0330621-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0330622-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0330623-3-prime-utr Drosophila melanogaster

Interactions

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Other

0 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
36238 NCBI Entrez Gene identifiers FBgn0000581
62026 BioGRID FBgn0000581

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0000581 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1628.0
FBgn0000581 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 1077.0
FBgn0000581 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1119.0
FBgn0000581 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 924.0
FBgn0000581 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 997.0
FBgn0000581 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 1082.0
FBgn0000581 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 1518.0
FBgn0000581 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 1350.0
FBgn0000581 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 1030.0
FBgn0000581 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1235.0
FBgn0000581 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1285.0
FBgn0000581 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 909.0
FBgn0000581 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1136.0
FBgn0000581 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 1985.0
FBgn0000581 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 1248.0
FBgn0000581 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 1133.0
FBgn0000581 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1140.0
FBgn0000581 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1626.0
FBgn0000581 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1357.0
FBgn0000581 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1223.0
FBgn0000581 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 1333.0
FBgn0000581 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 1774.0
FBgn0000581 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 841.0
FBgn0000581 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1063.0
FBgn0000581 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 2272.0
FBgn0000581 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 4458.0
FBgn0000581 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 3936.0
FBgn0000581 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 2804.0
FBgn0000581 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1866.0
FBgn0000581 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1827.0

16 Introns

DB identifier
Organism . Name
intron_FBgn0000581:1_FBgn0000581:5 Drosophila melanogaster
intron_FBgn0000581:5_FBgn0000581:6 Drosophila melanogaster
intron_FBgn0000581:6_FBgn0000581:7 Drosophila melanogaster
intron_FBgn0000581:7_FBgn0000581:8 Drosophila melanogaster
intron_FBgn0000581:8_FBgn0000581:9 Drosophila melanogaster
intron_FBgn0000581:9_FBgn0000581:11 Drosophila melanogaster
intron_FBgn0000581:11_FBgn0000581:12 Drosophila melanogaster
intron_FBgn0000581:12_FBgn0000581:13 Drosophila melanogaster
intron_FBgn0000581:13_FBgn0000581:14 Drosophila melanogaster
intron_FBgn0000581:14_FBgn0000581:16 Drosophila melanogaster
intron_FBgn0000581:14_FBgn0000581:15 Drosophila melanogaster
intron_FBgn0000581:4_FBgn0000581:5 Drosophila melanogaster
intron_FBgn0000581:8_FBgn0000581:10 Drosophila melanogaster
intron_FBgn0000581:10_FBgn0000581:12 Drosophila melanogaster
intron_FBgn0000581:3_FBgn0000581:5 Drosophila melanogaster
intron_FBgn0000581:2_FBgn0000581:5 Drosophila melanogaster

51 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage E(Pc) none -0.036342742   19067489
Lipid storage E(Pc) none 0.23658976   19067489
Lipid storage E(Pc) none 0.687486099   19067489
Lipid storage E(Pc) none 0.867707352   19067489
ERK signaling E(Pc) ERK activation increased strong   17086199
Cytokinesis regulation E(Pc) Binucleate cells weak   15547975
L. monocytogenes infection E(Pc) Escape pff LLO- strain **   16157870
Wnt signaling E(Pc) Increased Wnt reporter activity 3.7   15817814
Hedgehog signaling E(Pc) Decreased Hedgehog reporter activity -2.38   16311596
Mycobacterial infection (1) - M. fortuitum infection E(Pc) Decreased M. fortuitum intracellular infection 5.5 measurement after 3 days 16020694
Constitutive protein secretion and Golgi organization (1) E(Pc) Decreased horseradish peroxidase protein expression sp   16452979
Constitutive protein secretion and Golgi organization (1) E(Pc) Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) E(Pc) none sp   16496002
Cell size and cell-cycle regulation (1) E(Pc) none sp   16496002
Cell size and cell-cycle regulation (1) E(Pc) none sp   16496002
Dendrite pattern formation E(Pc) none np   16547170
Combinatorial effect with methyl methanesulphonate (1) E(Pc) none sp   19543366
Muscle morphogenesis and function (1) E(Pc) none np   20220848
Muscle morphogenesis and function (1) E(Pc) Lethal np   20220848
Heat nociception (1) E(Pc) none -0.34   21074052
Regulated secretory pathway biogenesis (1) E(Pc) none 0.8   21149569
Heart development and function (1) E(Pc) none 1   20371351
Serratia marcescens infection (1) E(Pc) none -0.647058823529411   19520911
Serratia marcescens infection (1) E(Pc) none -0.166666666666666   19520911
Notch pathway regulation (4) E(Pc) Completely lethal (pupal) sp   19363474
Notch pathway regulation (4) E(Pc) Bristle morphology defects, notum malformation death sp   19363474
Notch induced transcription E(Pc) Downregulation of Notch pathway after Notch stimulation -2.5152 N(delta)ecn Notch stimulation 20959007
Notch induced transcription E(Pc) none -0.56752 N(delta)ecn Notch stimulation 20959007
Notch induced transcription E(Pc) none -0.7559 without Notch stimulation 20959007
Hh pathway regulation E(Pc) Downregulation of Hh pathway -0.267048978656202   17903264

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