modENCODE |  Help |  blog

Gene : l(1)dd4 D. melanogaster

DB identifier  ? FBgn0001612 Secondary Identifier  ? CG10988
Name  ? lethal (1) discs degenerate 4 Source  FlyBase
  • synonyms:
  • FBgn0001612,
  • FBan0010988,
  • l(1)d.deg.4,
  • Dgrips91,
  • l(1)G0122,
  • FBgn0026429,
  • anon-WO03040301.197,
  • Dgrip9,
  • CG10988,
  • l(1)dd4,
  • GCP3,
  • FBgn0040196,
  • Dd4,
  • gamma-tubulin ring protein 91,
  • DGrip91,
  • l(1)d deg-4,
  • FBgn0066830,
  • GRIP91,
  • l(1)d.deg.-4

Sequence Feature Displayer

Publication Counts Displayer

Genomics

Gene Ontology Displayer

Homologue Displayer

Mod Mine G Browse Displayer

Overlapping Features Displayer

Regulatory Regions Displayer

20 Alleles

DB identifier Symbol Allele Class Organism
FBal0245917 l(1)dd4[JF01719]   Drosophila melanogaster
FBal0159087 l(1)dd4[d09268]   Drosophila melanogaster
FBal0103767 l(1)dd4[G0122]   Drosophila melanogaster
FBal0215896 l(1)dd4[EY16898]   Drosophila melanogaster
FBal0120465 l(1)dd4[tBa]   Drosophila melanogaster
FBal0120466 l(1)dd4[+t9]   Drosophila melanogaster
FBal0120463 l(1)dd4[xr16]   Drosophila melanogaster
FBal0007456 l(1)dd4[S] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0120464 l(1)dd4[unspecified]   Drosophila melanogaster
FBal0007455 l(1)dd4[1]   Drosophila melanogaster
FBal0031610 l(1)dd4[3] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0031609 l(1)dd4[2]   Drosophila melanogaster
FBal0179182 l(1)dd4[T:Zzzz\FLAG]   Drosophila melanogaster
FBal0209838 l(1)dd4[GD1474]   Drosophila melanogaster
FBal0219552 l(1)dd4[su(Pl)]   Drosophila melanogaster
FBal0227473 l(1)dd4[CB-0840-3]   Drosophila melanogaster
FBal0227474 l(1)dd4[NP1023]   Drosophila melanogaster
FBal0227475 l(1)dd4[NP1519]   Drosophila melanogaster
FBal0227476 l(1)dd4[5-HA-2733]   Drosophila melanogaster
FBal0231360 l(1)dd4[KK101573]   Drosophila melanogaster

66 Clones

Secondary Identifier DB identifier
AT04877 FBcl0028693
EC13878 FBcl0068833
EC39977 FBcl0068851
GM14553 FBcl0146856
LD43640 FBcl0169882
LD42379 FBcl0171944
RE04256 FBcl0212145
FGM101H08 FBcl0389125
FGM236E10 FBcl0391987
RP001041648 FBcl0501084
RP001051962 FBcl0501079
RP001000832 FBcl0501117
RP001012365 FBcl0501069
RP001044363 FBcl0501070
RP001020070 FBcl0501071
RP001041519 FBcl0501073
RP001048757 FBcl0501072
RP001005356 FBcl0501074
RP001016079 FBcl0501075
RP001040992 FBcl0501076
RP001013806 FBcl0501077
RP001044488 FBcl0501078
RP001022861 FBcl0501080
RP001035116 FBcl0501081
RP001035680 FBcl0501082
RP001019627 FBcl0501083
RP001036275 FBcl0501085
RP001023941 FBcl0501086
RP001046042 FBcl0501087
RP001035754 FBcl0501088

5 Exons

DB identifier Symbol
FBgn0001612:3 l(1)dd4:3
FBgn0001612:4 l(1)dd4:4
FBgn0001612:5 l(1)dd4:5
FBgn0001612:2 l(1)dd4:2
FBgn0001612:1 l(1)dd4:1

1 Transcripts

DB identifier Gene
FBtr0073841 l(1)dd4

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0073841-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0073841-3-prime-utr Drosophila melanogaster

Interactions

Cytoscape Network Displayer

 

Other

0 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
48481 NCBI Entrez Gene identifiers FBgn0001612
71426 BioGRID FBgn0001612

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0001612 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 415.0
FBgn0001612 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 545.0
FBgn0001612 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 346.0
FBgn0001612 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 401.0
FBgn0001612 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 404.0
FBgn0001612 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 321.0
FBgn0001612 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 362.0
FBgn0001612 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 443.0
FBgn0001612 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 165.0
FBgn0001612 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 412.0
FBgn0001612 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 387.0
FBgn0001612 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 233.0
FBgn0001612 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 214.0
FBgn0001612 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 199.0
FBgn0001612 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 519.0
FBgn0001612 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 301.0
FBgn0001612 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 594.0
FBgn0001612 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 532.0
FBgn0001612 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 293.0
FBgn0001612 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 301.0
FBgn0001612 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 346.0
FBgn0001612 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 408.0
FBgn0001612 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 398.0
FBgn0001612 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 346.0
FBgn0001612 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 399.0
FBgn0001612 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 1274.0
FBgn0001612 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 497.0
FBgn0001612 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 277.0
FBgn0001612 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 375.0
FBgn0001612 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 268.0

4 Introns

DB identifier
Organism . Name
intron_FBgn0001612:5_FBgn0001612:4 Drosophila melanogaster
intron_FBgn0001612:4_FBgn0001612:3 Drosophila melanogaster
intron_FBgn0001612:3_FBgn0001612:2 Drosophila melanogaster
intron_FBgn0001612:2_FBgn0001612:1 Drosophila melanogaster

23 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage l(1)dd4 none -0.013525091   19067489
Lipid storage l(1)dd4 none -0.745763039   19067489
Lipid storage l(1)dd4 none -1.826696847   19067489
Lipid storage l(1)dd4 none 1.521314501   19067489
ERK signaling l(1)dd4 ERK activation increased weak   17086199
Cell size and cell-cycle regulation (1) l(1)dd4 none sp   16496002
Mitosis l(1)dd4 Dim gamma-tubulin (centrosome+spindle) np   17412918
Spindle pole organization l(1)dd4 Monopolar/anastral np   18388316
Muscle morphogenesis and function (1) l(1)dd4 none np   20220848
Heat nociception (1) l(1)dd4 Increased noxious heat avoidance 1.75   21074052
Heart development and function (1) l(1)dd4 none 1   20371351
Serratia marcescens infection (1) l(1)dd4 none 0.921052631578947   19520911
Notch pathway regulation (4) l(1)dd4 Gain of bristles 1   19363474
Self-renewal and differentiation in neural stem cells l(1)dd4 GFP aggregates number, GFP aggregates size, ganglion mother cell shorter lineages, neuroblast underproliferation, lethal sp   21549331
Notch pathway regulation (1) l(1)dd4 Upregulation of Notch pathway np   20493818
Adiposity regulation (1) l(1)dd4 none -0.23   20074523
RTK-Ras-ERK pathway regulation (1) l(1)dd4 Increased ERK phosphorylation after EGF stimulation 1.95 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) l(1)dd4 none 0.18 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) l(1)dd4 none -0.06 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) l(1)dd4 none 1.15 30 minutes sSpitz stimulation 22028469
Hippo pathway regulation l(1)dd4 none 0.79   23263283
Muscle development and maintenance l(1)dd4 Pupal lethal sp  
Muscle maintenance l(1)dd4 none sp  

0 Submissions