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Gene : Pka-C2 D. melanogaster

DB identifier  ? FBgn0000274 Secondary Identifier  ? CG12066
Name  ? cAMP-dependent protein kinase 2 Source  FlyBase
  • synonyms:
  • FBgn0000274,
  • PKA,
  • Pka-C2,
  • DC1,
  • cAMP-dependent protein kinase type II,
  • CdkB,
  • FBan0012066,
  • CG12066,
  • DC1a,
  • PKA C2

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6 Alleles

DB identifier Symbol Allele Class Organism
FBal0245712 Pka-C2[JF01448]   Drosophila melanogaster
FBal0245941 Pka-C2[JF01756]   Drosophila melanogaster
FBal0208082 Pka-C2[GD4649]   Drosophila melanogaster
FBal0208083 Pka-C2[GD4723]   Drosophila melanogaster
FBal0271094 Pka-C2[NIG.12066R]   Drosophila melanogaster
FBal0236665 Pka-C2[KK110127]   Drosophila melanogaster

7 Clones

Secondary Identifier DB identifier
AT09739 FBcl0036391
AT16569 FBcl0036617
AT10952 FBcl0036833
bs84c07 FBcl0055827
bs60f10 FBcl0056185
EC25478 FBcl0070615
LP17872 FBcl0181620

6 Exons

DB identifier Symbol
FBgn0000274:6 Pka-C2:6
FBgn0000274:4 Pka-C2:4
FBgn0000274:3 Pka-C2:3
FBgn0000274:2 Pka-C2:2
FBgn0000274:1 Pka-C2:1
FBgn0000274:5 Pka-C2:5

2 Transcripts

DB identifier Gene
FBtr0335454 Pka-C2
FBtr0085727 Pka-C2

4 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0085727-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0335454-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0085727-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0335454-3-prime-utr Drosophila melanogaster

Interactions

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Other

0 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
43644 NCBI Entrez Gene identifiers FBgn0000274
68495 BioGRID FBgn0000274

10 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0000274 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 107.0
FBgn0000274 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 85.0
FBgn0000274 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 98.0
FBgn0000274 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 112.0
FBgn0000274 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 55.0
FBgn0000274 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 98.0
FBgn0000274 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 37.0
FBgn0000274 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 178.0
FBgn0000274 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 44.0
FBgn0000274 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 88.0
FBgn0000274 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 128.0
FBgn0000274 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 115.0
FBgn0000274 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 83.0
FBgn0000274 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 67.0
FBgn0000274 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 63.0
FBgn0000274 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 201.0
FBgn0000274 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 75.0
FBgn0000274 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 274.0
FBgn0000274 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 121.0
FBgn0000274 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 70.0
FBgn0000274 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 148.0
FBgn0000274 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 43.0
FBgn0000274 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 65.0
FBgn0000274 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 33.0
FBgn0000274 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 180.0
FBgn0000274 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 70.0
FBgn0000274 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 212.0
FBgn0000274 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 138.0
FBgn0000274 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 44.0
FBgn0000274 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 45.0

5 Introns

DB identifier
Organism . Name
intron_FBgn0000274:5_FBgn0000274:4 Drosophila melanogaster
intron_FBgn0000274:4_FBgn0000274:3 Drosophila melanogaster
intron_FBgn0000274:3_FBgn0000274:2 Drosophila melanogaster
intron_FBgn0000274:2_FBgn0000274:1 Drosophila melanogaster
intron_FBgn0000274:6_FBgn0000274:4 Drosophila melanogaster

27 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Pka-C2 none 1.283048822   19067489
Lipid storage Pka-C2 none -2.008343469   19067489
Lipid storage Pka-C2 none 0   19067489
Lipid storage Pka-C2 none 0.545350531   19067489
Cell cycle regulation (1) Pka-C2 All mitotic defects, spindle defects, chromosome defects sp   15616552
Cell cycle regulation (2) Pka-C2 none np   15616552
Cytokinesis regulation Pka-C2 Binucleate cells with large, diffuse DNA medium   15547975
Cell size and cell-cycle regulation (1) Pka-C2 none sp   16496002
Mitochondrial biogenesis and function Pka-C2 Decreased mitochondrial citrate synthase activity 0.797   18042644
Muscle morphogenesis and function (1) Pka-C2 Flightless np   20220848
Muscle morphogenesis and function (1) Pka-C2 none np   20220848
Muscle morphogenesis and function (4) Pka-C2 Frayed myofibrils np   20220848
Heat nociception (1) Pka-C2 none -1.17   21074052
Serratia marcescens infection (1) Pka-C2 none 1.1078431372549   19520911
Notch pathway regulation (4) Pka-C2 none 0   19363474
Notch pathway regulation (4) Pka-C2 Loss of bristles, notum malformation death sp   19363474
Self-renewal and differentiation in neural stem cells Pka-C2 GFP aggregates number, GFP aggregates size, neuroblast abnormally large cell size, neuroblast larger cell size, neuroblast cell shape, ganglion mother cell shorter lineages, extremely increased neuroblast cell size without neuroblast loss, neuroblast unde sp   21549331
Adiposity regulation (1) Pka-C2 none -0.118   20074523
S2 cell spreading Pka-C2 none np   21041442
Actin organization and cell morphology (1) Pka-C2 none np   19265526
Actin organization and cell morphology (2) Pka-C2 none np   19265526
Actin organization and cell morphology (3) Pka-C2 none np   19265526
Actin organization and cell morphology (4) Pka-C2 none np   19265526
Actin organization and cell morphology (5) Pka-C2 none np   19265526
Actin organization and cell morphology (6) Pka-C2 none np   19265526
Vaccinia virus infection Pka-C2 none sp   20585561
Hippo pathway regulation Pka-C2 none -0.06   23263283

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