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Gene : Pk92B D. melanogaster

DB identifier  ? FBgn0014006 Secondary Identifier  ? CG4720
Name  ? Protein kinase at 92B Source  FlyBase
  • synonyms:
  • FBgn0014006,
  • DPk92B/ASK1,
  • pk92B,
  • MEKK5/ASK1,
  • CG4720,
  • D-ASK,
  • DASK,
  • DASK1,
  • ASK1,
  • Apoptotic signal-regulating kinase 1,
  • FBan0004720

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13 Alleles

DB identifier Symbol Allele Class Organism
FBal0260470 Pk92B[MI02915]   Drosophila melanogaster
FBal0259241 Pk92B[KK102892]   Drosophila melanogaster
FBal0147682 Pk92B[dsRNA.cCa]   Drosophila melanogaster
FBal0152302 Pk92B[K618M.GMR]   Drosophila melanogaster
FBal0152303 Pk92B[GMR.PK]   Drosophila melanogaster
FBal0262709 Pk92B[GL00238]   Drosophila melanogaster
FBal0152301 Pk92B[K618M.Scer\UAS]   Drosophila melanogaster
FBal0152300 Pk92B[Scer\UAS.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0218754 Pk92B[MB06487]   Drosophila melanogaster
FBal0263920 Pk92B[DeltaN.Scer\UAS.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0263921 Pk92B[dsRNA.Scer\UAS]   Drosophila melanogaster
FBal0208080 Pk92B[GD11408]   Drosophila melanogaster
FBal0248219 Pk92B[HMS00464]   Drosophila melanogaster

46 Clones

Secondary Identifier DB identifier
EK190912 FBcl0058312
EK196358 FBcl0058392
EK044241 FBcl0058438
EK187412 FBcl0058734
EK148661 FBcl0058756
EK263222 FBcl0059932
GH14419 FBcl0116151
GH25453 FBcl0116153
GH24527 FBcl0116157
LD40486 FBcl0169282
LP18251 FBcl0184390
LP13749 FBcl0184392
RE63403 FBcl0210601
RE65490 FBcl0210602
RE72526 FBcl0210611
RE38981 FBcl0210613
RE59133 FBcl0210615
RE29304 FBcl0210652
RE51420 FBcl0210660
RE29642 FBcl0210665
RE60627 FBcl0210712
RE48620 FBcl0210879
RE33727 FBcl0210881
RH03216 FBcl0253865
RH51434 FBcl0253969
SD21868 FBcl0292066
SD22069 FBcl0292068
UT01008 FBcl0293064
EC053499 FBcl0300057
EC055783 FBcl0300058

11 Exons

DB identifier Symbol
FBgn0014006:1 Pk92B:1
FBgn0014006:3 Pk92B:3
FBgn0014006:5 Pk92B:5
FBgn0014006:6 Pk92B:6
FBgn0014006:7 Pk92B:7
FBgn0014006:8 Pk92B:8
FBgn0014006:9 Pk92B:9
FBgn0014006:10 Pk92B:10
FBgn0014006:11 Pk92B:11
FBgn0014006:2 Pk92B:2
FBgn0014006:4 Pk92B:4

2 Transcripts

DB identifier Gene
FBtr0300256 Pk92B
FBtr0083819 Pk92B

4 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0083819-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0300256-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0083819-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0300256-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
42366 NCBI Entrez Gene identifiers FBgn0014006
67355 BioGRID FBgn0014006

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0014006 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 638.0
FBgn0014006 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 685.0
FBgn0014006 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 442.0
FBgn0014006 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 773.0
FBgn0014006 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 891.0
FBgn0014006 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 395.0
FBgn0014006 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 987.0
FBgn0014006 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 1192.0
FBgn0014006 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 596.0
FBgn0014006 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 845.0
FBgn0014006 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 861.0
FBgn0014006 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 636.0
FBgn0014006 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 999.0
FBgn0014006 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 970.0
FBgn0014006 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 659.0
FBgn0014006 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 650.0
FBgn0014006 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 701.0
FBgn0014006 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1185.0
FBgn0014006 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1098.0
FBgn0014006 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 419.0
FBgn0014006 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 879.0
FBgn0014006 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 617.0
FBgn0014006 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 591.0
FBgn0014006 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1018.0
FBgn0014006 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1146.0
FBgn0014006 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 1858.0
FBgn0014006 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 374.0
FBgn0014006 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 485.0
FBgn0014006 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 445.0
FBgn0014006 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 528.0

11 Introns

DB identifier
Organism . Name
intron_FBgn0014006:1_FBgn0014006:2 Drosophila melanogaster
intron_FBgn0014006:2_FBgn0014006:4 Drosophila melanogaster
intron_FBgn0014006:4_FBgn0014006:5 Drosophila melanogaster
intron_FBgn0014006:5_FBgn0014006:6 Drosophila melanogaster
intron_FBgn0014006:6_FBgn0014006:7 Drosophila melanogaster
intron_FBgn0014006:7_FBgn0014006:8 Drosophila melanogaster
intron_FBgn0014006:8_FBgn0014006:9 Drosophila melanogaster
intron_FBgn0014006:9_FBgn0014006:10 Drosophila melanogaster
intron_FBgn0014006:10_FBgn0014006:11 Drosophila melanogaster
intron_FBgn0014006:1_FBgn0014006:3 Drosophila melanogaster
intron_FBgn0014006:3_FBgn0014006:5 Drosophila melanogaster

30 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Pk92B none 1.101814373   19067489
Lipid storage Pk92B none 0.011284443   19067489
Lipid storage Pk92B none -0.278463645   19067489
Lipid storage Pk92B none -0.075242992   19067489
Cell morphology Pk92B Morphology np   14527345
Cell cycle regulation (1) Pk92B Increased G1 DNA content sp   15616552
Cell cycle regulation (2) Pk92B Increased G1 DNA content, increased cell size np   15616552
Cell size and cell-cycle regulation (1) Pk92B none sp   16496002
Muscle morphogenesis and function (1) Pk92B Lethal np   20220848
Muscle morphogenesis and function (1) Pk92B Lethal np   20220848
Heat nociception (1) Pk92B none -1.17   21074052
Heat nociception (1) Pk92B Developmentally lethal 0   21074052
Heart development and function (1) Pk92B none 0.7   20371351
Serratia marcescens infection (1) Pk92B none 0.216666666666666   19520911
Notch pathway regulation (4) Pk92B none 0   19363474
Notch pathway regulation (4) Pk92B none 0   19363474
Pol II elongation Pk92B Decreased Hsp70 mRNA expression 61 20 min heat shock 19279664
Adiposity regulation (1) Pk92B none -0.588   20074523
Actin organization and cell morphology (1) Pk92B none np   19265526
Actin organization and cell morphology (2) Pk92B none np   19265526
Actin organization and cell morphology (3) Pk92B none np   19265526
Actin organization and cell morphology (4) Pk92B none np   19265526
Actin organization and cell morphology (5) Pk92B none np   19265526
Actin organization and cell morphology (6) Pk92B none np   19265526
RTK-Ras-ERK pathway regulation (1) Pk92B none 0.23 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) Pk92B none 0.39 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Pk92B none -0.57 30 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Pk92B Decreased ERK phosphorylation after sSpitz and EGF stimulation -1.58 10 minutes sSpitz stimulation 22028469
Hippo pathway regulation Pk92B none 1.1   23263283
Glycosylation regulation (4) Pk92B none sp   21203496

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