modENCODE |  Help |  blog

Gene : MAPk-Ak2 D. melanogaster

DB identifier  ? FBgn0013987 Secondary Identifier  ? CG3086
Name  ? MAP kinase activated protein-kinase-2 Source  FlyBase
  • synonyms:
  • MAPKAP,
  • dMK2,
  • FBgn0029802,
  • CG3086,
  • MAPKAPK-2,
  • MK2,
  • MAP kinase activated protein kinase-2,
  • DmMAPKAPK-2,
  • MAPk-Ak2,
  • FBan0003086,
  • FBgn0013987

Sequence Feature Displayer

Publication Counts Displayer

Genomics

Gene Ontology Displayer

Homologue Displayer

Mod Mine G Browse Displayer

Overlapping Features Displayer

Regulatory Regions Displayer

18 Alleles

DB identifier Symbol Allele Class Organism
FBal0258773 MAPk-Ak2[KK100594]   Drosophila melanogaster
FBal0248528 MAPk-Ak2[5B]   Drosophila melanogaster
FBal0267164 MAPk-Ak2[GE3296]   Drosophila melanogaster
FBal0267165 MAPk-Ak2[Delta43] amorphic allele - molecular evidence Drosophila melanogaster
FBal0267166 MAPk-Ak2[Delta41] hypomorphic allele - molecular evidence Drosophila melanogaster
FBal0267167 MAPk-Ak2[Delta12] hypomorphic allele - molecular evidence Drosophila melanogaster
FBal0267168 MAPk-Ak2[Delta38]   Drosophila melanogaster
FBal0267169 MAPk-Ak2[Delta1A]   Drosophila melanogaster
FBal0267170 MAPk-Ak2[+tSa]   Drosophila melanogaster
FBal0267171 MAPk-Ak2[Scer\UAS.cSa]   Drosophila melanogaster
FBal0267172 MAPk-Ak2[K49A.Scer\UAS]   Drosophila melanogaster
FBal0267173 MAPk-Ak2[T:Avic\GFP]   Drosophila melanogaster
FBal0278766 MAPk-Ak2[GL01326]   Drosophila melanogaster
FBal0262694 MAPk-Ak2[GL00223]   Drosophila melanogaster
FBal0287104 MAPk-Ak2[Scer\UAS.ORF]   Drosophila melanogaster
FBal0287105 MAPk-Ak2[Scer\UAS.ORF.T:Ivir\HA1]   Drosophila melanogaster
FBal0247847 MAPk-Ak2[G265]   Drosophila melanogaster
FBal0207539 MAPk-Ak2[GD1597]   Drosophila melanogaster

88 Clones

Secondary Identifier DB identifier
EK141161 FBcl0067698
EK125732 FBcl0073710
EK154250 FBcl0076006
EK177831 FBcl0077516
EK063522 FBcl0078042
EK129932 FBcl0079160
EK242311 FBcl0079352
EK116532 FBcl0082190
EK110624 FBcl0083850
EP19108 FBcl0083901
EP04064 FBcl0084157
EK122164 FBcl0084580
EK180816 FBcl0088584
EK125725 FBcl0088982
EK040525 FBcl0090190
GH03081 FBcl0103153
GM32414 FBcl0146889
HL03857 FBcl0148578
LD17156 FBcl0151005
LD05106 FBcl0151230
LD09863 FBcl0151272
LD02608 FBcl0151293
LD05456 FBcl0151365
LD07089 FBcl0151397
LD01955 FBcl0152042
LD45217 FBcl0163386
LD26767 FBcl0163438
LD43882 FBcl0163817
LP09187 FBcl0179295
LP19289 FBcl0179317

6 Exons

DB identifier Symbol
FBgn0013987:6 MAPk-Ak2:6
FBgn0013987:3 MAPk-Ak2:3
FBgn0013987:2 MAPk-Ak2:2
FBgn0013987:1 MAPk-Ak2:1
FBgn0013987:5 MAPk-Ak2:5
FBgn0013987:4 MAPk-Ak2:4

3 Transcripts

DB identifier Gene
FBtr0070837 MAPk-Ak2
FBtr0070839 MAPk-Ak2
FBtr0302940 MAPk-Ak2

6 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0070837-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0070839-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0302940-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0070837-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0070839-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0302940-3-prime-utr Drosophila melanogaster

Interactions

Cytoscape Network Displayer

 

Other

43 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
44573 NCBI Entrez Gene identifiers FBgn0013987
69137 BioGRID FBgn0013987

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0013987 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1864.0
FBgn0013987 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 1613.0
FBgn0013987 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1214.0
FBgn0013987 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1390.0
FBgn0013987 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1323.0
FBgn0013987 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 2361.0
FBgn0013987 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 3396.0
FBgn0013987 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 2263.0
FBgn0013987 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 1535.0
FBgn0013987 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 2088.0
FBgn0013987 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 2412.0
FBgn0013987 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 1427.0
FBgn0013987 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 2053.0
FBgn0013987 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 2237.0
FBgn0013987 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 2321.0
FBgn0013987 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 1681.0
FBgn0013987 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 2557.0
FBgn0013987 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 2443.0
FBgn0013987 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 2906.0
FBgn0013987 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1446.0
FBgn0013987 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 1807.0
FBgn0013987 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 1562.0
FBgn0013987 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 1393.0
FBgn0013987 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1513.0
FBgn0013987 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1967.0
FBgn0013987 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 3192.0
FBgn0013987 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 1700.0
FBgn0013987 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 983.0
FBgn0013987 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 761.0
FBgn0013987 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1144.0

5 Introns

DB identifier
Organism . Name
intron_FBgn0013987:4_FBgn0013987:3 Drosophila melanogaster
intron_FBgn0013987:3_FBgn0013987:2 Drosophila melanogaster
intron_FBgn0013987:2_FBgn0013987:1 Drosophila melanogaster
intron_FBgn0013987:6_FBgn0013987:3 Drosophila melanogaster
intron_FBgn0013987:5_FBgn0013987:3 Drosophila melanogaster

30 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage MAPk-Ak2 none 0.278614289   19067489
Lipid storage MAPk-Ak2 none 0.227979792   19067489
Cell morphology MAPk-Ak2 Morphology np   14527345
Cell cycle regulation (1) MAPk-Ak2 Spindle defects, chromosome alignment defects sp   15616552
Cell cycle regulation (2) MAPk-Ak2 none np   15616552
Cell size and cell-cycle regulation (1) MAPk-Ak2 Decreased G2 DNA content sp   16496002
Cell size and cell-cycle regulation (1) MAPk-Ak2 none sp   16496002
Cell size and cell-cycle regulation (1) MAPk-Ak2 none sp   16496002
Cell size and cell-cycle regulation (2) MAPk-Ak2 none 1.374   16496002
Cell size and cell-cycle regulation (3) MAPk-Ak2 none 457   16496002
Cell size and cell-cycle regulation (4) MAPk-Ak2 none below threshold   16496002
Muscle morphogenesis and function (1) MAPk-Ak2 none np   20220848
Muscle morphogenesis and function (1) MAPk-Ak2 none np   20220848
Heat nociception (1) MAPk-Ak2 none -0.72   21074052
Heat nociception (1) MAPk-Ak2 none -0.4   21074052
Heart development and function (1) MAPk-Ak2 none 1   20371351
Heart development and function (1) MAPk-Ak2 none 1   20371351
Serratia marcescens infection (1) MAPk-Ak2 none 0.552631578947368   19520911
Notch pathway regulation (4) MAPk-Ak2 none 0   19363474
Notch pathway regulation (4) MAPk-Ak2 none 0   19363474
Pol II elongation MAPk-Ak2 none 141 20 min heat shock 19279664
Adiposity regulation (1) MAPk-Ak2 none -0.185   20074523
Actin organization and cell morphology (1) MAPk-Ak2 none np   19265526
Actin organization and cell morphology (2) MAPk-Ak2 none np   19265526
Actin organization and cell morphology (3) MAPk-Ak2 none np   19265526
Actin organization and cell morphology (4) MAPk-Ak2 none np   19265526
Actin organization and cell morphology (5) MAPk-Ak2 none np   19265526
Actin organization and cell morphology (6) MAPk-Ak2 none np   19265526
Vaccinia virus infection MAPk-Ak2 none sp   20585561
Hippo pathway regulation MAPk-Ak2 Downregulation of Hippo pathway 6.37   23263283

0 Submissions