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Gene : MEP-1 D. melanogaster

DB identifier  ? FBgn0035357 Secondary Identifier  ? CG1244
Source  FlyBase
  • synonyms:
  • anon-WO0118547.584,
  • CG1244,
  • FBan0001244,
  • FBgn0035357,
  • Q0E8J0_DROME,
  • anon-EST:Liang-1.37,
  • clone 1.37,
  • dMEP-1,
  • MEP-1,
  • MEP1,
  • FBgn0025995,
  • FBgn0061858

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9 Alleles

DB identifier Symbol Allele Class Organism
FBal0257228 MEP-1[HMS00540]   Drosophila melanogaster
FBal0157209 MEP-1[EY04917]   Drosophila melanogaster
FBal0122311 MEP-1[GTD74-56]   Drosophila melanogaster
FBal0187465 MEP-1[f05384]   Drosophila melanogaster
FBal0216983 MEP-1[C240]   Drosophila melanogaster
FBal0262786 MEP-1[GL00319]   Drosophila melanogaster
FBal0261549 MEP-1[CPTI003583]   Drosophila melanogaster
FBal0199812 MEP-1[GD7728]   Drosophila melanogaster
FBal0222948 MEP-1[5-HA-1819]   Drosophila melanogaster

125 Clones

Secondary Identifier DB identifier
AT16816 FBcl0010319
EK164517 FBcl0092126
EK134011 FBcl0092134
EK283640 FBcl0092150
EK088520 FBcl0092166
EK066810 FBcl0092214
EK043352 FBcl0092226
EK177436 FBcl0092230
EK305637 FBcl0092262
EK282511 FBcl0092278
GH05069 FBcl0116823
GH11755 FBcl0132311
GM16118 FBcl0144619
GM22759 FBcl0144630
GM24025 FBcl0144631
HL01345 FBcl0150542
LD06211 FBcl0161603
LD14308 FBcl0161606
LD04305 FBcl0161607
LD03723 FBcl0161609
LD18519 FBcl0161610
LD20679 FBcl0161611
LD16663 FBcl0161615
LD12540 FBcl0161618
LD06872 FBcl0161620
LD03754 FBcl0161622
LD07938 FBcl0161623
LD10227 FBcl0161624
LD13110 FBcl0161626
LD14091 FBcl0161628

14 Exons

DB identifier Symbol
FBgn0035357:1 MEP-1:1
FBgn0035357:3 MEP-1:3
FBgn0035357:5 MEP-1:5
FBgn0035357:9 MEP-1:9
FBgn0035357:10 MEP-1:10
FBgn0035357:11 MEP-1:11
FBgn0035357:12 MEP-1:12
FBgn0035357:13 MEP-1:13
FBgn0035357:14 MEP-1:14
FBgn0035357:4 MEP-1:4
FBgn0035357:6 MEP-1:6
FBgn0035357:7 MEP-1:7
FBgn0035357:8 MEP-1:8
FBgn0035357:2 MEP-1:2

7 Transcripts

DB identifier Gene
FBtr0072931 MEP-1
FBtr0072932 MEP-1
FBtr0072933 MEP-1
FBtr0290340 MEP-1
FBtr0072936 MEP-1
FBtr0072935 MEP-1
FBtr0072934 MEP-1

14 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0072931-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0072932-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0072933-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0072934-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0072935-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0072936-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0290340-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0072931-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0072932-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0072933-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0072934-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0072935-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0072936-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0290340-3-prime-utr Drosophila melanogaster

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0 Pathways

3 Cross References

Identifier
Source . Name

Subject . Primary Identifier
38327, 7354428 NCBI Entrez Gene identifiers FBgn0035357
38327 NCBI Entrez Gene identifiers FBgn0035357
63832 BioGRID FBgn0035357

10 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0035357 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1276.0
FBgn0035357 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 1723.0
FBgn0035357 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1256.0
FBgn0035357 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1258.0
FBgn0035357 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1242.0
FBgn0035357 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 1234.0
FBgn0035357 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 2506.0
FBgn0035357 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 2410.0
FBgn0035357 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 1102.0
FBgn0035357 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 2068.0
FBgn0035357 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1652.0
FBgn0035357 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 867.0
FBgn0035357 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1425.0
FBgn0035357 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 1204.0
FBgn0035357 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 1430.0
FBgn0035357 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 1678.0
FBgn0035357 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1677.0
FBgn0035357 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1451.0
FBgn0035357 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 796.0
FBgn0035357 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1193.0
FBgn0035357 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 1279.0
FBgn0035357 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 1639.0
FBgn0035357 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 1494.0
FBgn0035357 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1772.0
FBgn0035357 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1794.0
FBgn0035357 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 4063.0
FBgn0035357 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 4015.0
FBgn0035357 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 3595.0
FBgn0035357 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 2157.0
FBgn0035357 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 2252.0

14 Introns

DB identifier
Organism . Name
intron_FBgn0035357:1_FBgn0035357:5 Drosophila melanogaster
intron_FBgn0035357:5_FBgn0035357:9 Drosophila melanogaster
intron_FBgn0035357:9_FBgn0035357:10 Drosophila melanogaster
intron_FBgn0035357:10_FBgn0035357:11 Drosophila melanogaster
intron_FBgn0035357:11_FBgn0035357:12 Drosophila melanogaster
intron_FBgn0035357:12_FBgn0035357:13 Drosophila melanogaster
intron_FBgn0035357:13_FBgn0035357:14 Drosophila melanogaster
intron_FBgn0035357:4_FBgn0035357:5 Drosophila melanogaster
intron_FBgn0035357:2_FBgn0035357:5 Drosophila melanogaster
intron_FBgn0035357:1_FBgn0035357:3 Drosophila melanogaster
intron_FBgn0035357:3_FBgn0035357:5 Drosophila melanogaster
intron_FBgn0035357:6_FBgn0035357:9 Drosophila melanogaster
intron_FBgn0035357:7_FBgn0035357:9 Drosophila melanogaster
intron_FBgn0035357:8_FBgn0035357:9 Drosophila melanogaster

25 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage MEP-1 none 2.499630216   19067489
Lipid storage MEP-1 none 0.481916585   19067489
Lipid storage MEP-1 none -0.020347046   19067489
Lipid storage MEP-1 none 0   19067489
Lipid storage MEP-1 none 2.544032134   19067489
Lipid storage MEP-1 none 1.539980062   19067489
Cell size and cell-cycle regulation (1) MEP-1 none sp   16496002
Dendrite pattern formation MEP-1 Decreased arborization, misrouting np   16547170
ato interactions MEP-1 none np sp 19165344
ato interactions MEP-1 none np sp 19165344
Heat nociception (1) MEP-1 none -0.79   21074052
Heat nociception (1) MEP-1 none -0.54   21074052
Heat nociception (1) MEP-1 none -0.79   21074052
Heat nociception (1) MEP-1 none -0.54   21074052
Serratia marcescens infection (1) MEP-1 none -1.025   19520911
PGN-induced dJNK phosphorylation MEP-1 Increased P-JNK protein expression with PGN 3.1 15 min PGN induction 19893628
PGN-induced dJNK phosphorylation MEP-1 Increased P-JNK protein expression with PGN 2.4 60 min PGN induction 19893628
Toll-dependent innate immune pathway regulation MEP-1 Downregulation of Toll pathway after hEGF stimulation -4.27   20375635
Notch pathway regulation (1) MEP-1 Upregulation of Notch pathway np   20493818
S2 cell spreading MEP-1 none np   21041442
RTK-Ras-ERK pathway regulation (1) MEP-1 none 1 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) MEP-1 none -0.05 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) MEP-1 Increased ERK phosphorylation after sSpitz and EGF stimulation 1.72 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) MEP-1 Increased ERK phosphorylation after sSpitz and EGF stimulation 1.76 30 minutes sSpitz stimulation 22028469
Hippo pathway regulation MEP-1 none 2.36   23263283

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