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Gene : CrebB D. melanogaster

DB identifier  ? FBgn0265784 Secondary Identifier  ? CG6103
Name  ? Cyclic-AMP response element binding protein B Source  FlyBase
  • synonyms:
  • CrebB17-A,
  • cAMP-response element-binding protein,
  • FBgn0014468,
  • CG6103,
  • dCREB-2a,
  • CREB,
  • FBan0006103,
  • blocker,
  • activator,
  • FBgn0004972,
  • CREB-B,
  • dCREB-2,
  • dCREB2,
  • dCREB2b,
  • n,
  • CRE-BP,
  • cAMP-response element binding protein,
  • dCrebB2,
  • l(1)17Af,
  • CrebB-17A,
  • Creb B 17A,
  • S162,
  • Creb2.b,
  • dCREB2a,
  • dCbz,
  • dCREB2-b,
  • lethal(1)17Af,
  • dCREB2-a,
  • cAMP response element-binding protein,
  • dCREB,
  • CREB2b,
  • cAMP-regulated enhancer-binding protein,
  • dCREB-B,
  • FBgn0265784,
  • CrebB-17B,
  • Cyclic-AMP response element binding protein B at 17B,
  • cyclic AMP response element binding protein,
  • CREB2a,
  • Cyclic-AMP response element binding protein B at 17A,
  • Creb17A,
  • Creb2-b,
  • CREB2,
  • FBgn0014467

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37 Alleles

DB identifier Symbol Allele Class Organism
FBal0284282 CrebB[G9627] hypomorphic allele - molecular evidence Drosophila melanogaster
FBal0038213 CrebB[b.hs]   Drosophila melanogaster
FBal0042458 CrebB[pka.hs]   Drosophila melanogaster
FBal0184293 CrebB[d01424]   Drosophila melanogaster
FBal0242682 CrebB[b.Scer\UAS]   Drosophila melanogaster
FBal0006239 CrebB[S162]   Drosophila melanogaster
FBal0060750 CrebB[Cbz.Scer\UAS]   Drosophila melanogaster
FBal0156763 CrebB[CK.hs]   Drosophila melanogaster
FBal0184292 CrebB[d06190]   Drosophila melanogaster
FBal0060749 CrebB[a.Scer\UAS]   Drosophila melanogaster
FBal0242176 CrebB[JF02494]   Drosophila melanogaster
FBal0219580 CrebB[+t.STOP]   Drosophila melanogaster
FBal0160684 CrebB[EY04780]   Drosophila melanogaster
FBal0226042 CrebB[d10931]   Drosophila melanogaster
FBal0214452 CrebB[GD1287]   Drosophila melanogaster
FBal0156762 CrebB[S231A.hs]   Drosophila melanogaster
FBal0280376 CrebB[Scer\UAS.b.cYa]   Drosophila melanogaster
FBal0267705 CrebB[DN.Scer\UAS]   Drosophila melanogaster
FBal0184294 CrebB[d00349]   Drosophila melanogaster
FBal0156761 CrebB[S240A.hs]   Drosophila melanogaster
FBal0219579 CrebB[+tIa]   Drosophila melanogaster
FBal0282863 CrebB[R]   Drosophila melanogaster
FBal0097378 CrebB[d.hs]   Drosophila melanogaster
FBal0060752 CrebB[B.Scer\UAS]   Drosophila melanogaster
FBal0184295 CrebB[cor.Scer\UAS]   Drosophila melanogaster
FBal0191015 CrebB[unspecified]   Drosophila melanogaster
FBal0038214 CrebB[mLZ.hs]   Drosophila melanogaster
FBal0184290 CrebB[mut.Scer\UAS]   Drosophila melanogaster
FBal0217148 CrebB[EP1378]   Drosophila melanogaster
FBal0226041 CrebB[d06196]   Drosophila melanogaster

18 Clones

Secondary Identifier DB identifier
DPiM_RT01009 FBcl0741328
RT01111 FBcl0383741
RT01009 FBcl0383742
RT01011 FBcl0383744
RP003349143 FBcl0484432
EP00449 FBcl0083627
GH26885 FBcl0107661
EK170541 FBcl0116638
RT01110 FBcl0383842
EK261938 FBcl0310395
Dmel_neb_014719_0355_3578 FBcl0367164
43156 FBcl0419911
163785 FBcl0462612
158982 FBcl0462712
56982 FBcl0462782
35654 FBcl0462790
214443.60 FBcl0462809
MIP12660 FBcl0703780

17 Exons

DB identifier Symbol
FBgn0265784:15 CrebB:15
FBgn0265784:6 CrebB:6
FBgn0265784:12 CrebB:12
FBgn0265784:1 CrebB:1
FBgn0265784:3 CrebB:3
FBgn0265784:8 CrebB:8
FBgn0265784:11 CrebB:11
FBgn0265784:13 CrebB:13
FBgn0265784:16 CrebB:16
FBgn0265784:5 CrebB:5
FBgn0265784:14 CrebB:14
FBgn0265784:2 CrebB:2
FBgn0265784:17 CrebB:17
FBgn0265784:4 CrebB:4
FBgn0265784:9 CrebB:9
FBgn0265784:7 CrebB:7
FBgn0265784:10 CrebB:10

10 Transcripts

DB identifier Gene
FBtr0074556 CrebB
FBtr0112878 CrebB
FBtr0310340 CrebB
FBtr0074555 CrebB
FBtr0074554 CrebB
FBtr0308232 CrebB
FBtr0074557 CrebB
FBtr0112877 CrebB
FBtr0310341 CrebB
FBtr0112879 CrebB

14 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0074555-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0074557-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0112878-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0112879-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0308232-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0310340-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0310341-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0074555-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0074557-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0112878-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0112879-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0308232-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0310340-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0310341-3-prime-utr Drosophila melanogaster

Interactions

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140 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
32817 NCBI Entrez Gene identifiers FBgn0265784
59134 BioGRID FBgn0265784

10 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from UniProt  
FlyBase fasta data set for Drosophila melanogaster  

0 Expression Scores

20 Introns

DB identifier
Organism . Name
intron_FBgn0265784:7_FBgn0265784:8 Drosophila melanogaster
intron_FBgn0265784:8_FBgn0265784:11 Drosophila melanogaster
intron_FBgn0265784:11_FBgn0265784:13 Drosophila melanogaster
intron_FBgn0265784:13_FBgn0265784:15 Drosophila melanogaster
intron_FBgn0265784:15_FBgn0265784:16 Drosophila melanogaster
intron_FBgn0265784:5_FBgn0265784:8 Drosophila melanogaster
intron_FBgn0265784:4_FBgn0265784:9 Drosophila melanogaster
intron_FBgn0265784:9_FBgn0265784:12 Drosophila melanogaster
intron_FBgn0265784:12_FBgn0265784:13 Drosophila melanogaster
intron_FBgn0265784:13_FBgn0265784:16 Drosophila melanogaster
intron_FBgn0265784:8_FBgn0265784:12 Drosophila melanogaster
intron_FBgn0265784:2_FBgn0265784:8 Drosophila melanogaster
intron_FBgn0265784:13_FBgn0265784:17 Drosophila melanogaster
intron_FBgn0265784:15_FBgn0265784:17 Drosophila melanogaster
intron_FBgn0265784:6_FBgn0265784:8 Drosophila melanogaster
intron_FBgn0265784:12_FBgn0265784:14 Drosophila melanogaster
intron_FBgn0265784:4_FBgn0265784:10 Drosophila melanogaster
intron_FBgn0265784:10_FBgn0265784:12 Drosophila melanogaster
intron_FBgn0265784:1_FBgn0265784:3 Drosophila melanogaster
intron_FBgn0265784:3_FBgn0265784:8 Drosophila melanogaster

6 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Dendrite pattern formation CrebB none np   16547170
RTK-Ras-ERK pathway regulation (1) CrebB Increased ERK phosphorylation after EGF stimulation 1.8 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) CrebB none 0.02 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) CrebB none 1.41 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) CrebB Increased ERK phosphorylation after sSpitz and EGF stimulation 1.55 30 minutes sSpitz stimulation 22028469
Hippo pathway regulation CrebB none -0.41   23263283

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