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Gene : wds D. melanogaster

DB identifier  ? FBgn0040066 Secondary Identifier  ? CG17437
Name  ? will die slowly Source  FlyBase
  • synonyms:
  • l(1)16-94,
  • FBgn0027252,
  • WDS,
  • FBgn0040066,
  • zw-8,
  • l(1)G0251,
  • WDR5,
  • l(1)3Ad,
  • lethal(1)3Ad,
  • zw8,
  • FBgn0029626,
  • FBgn0001403,
  • EG:BACR25B3.7,
  • FBan0017437,
  • l(1)zw8,
  • CG17437

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58 Alleles

DB identifier Symbol Allele Class Organism
FBal0283183 wds[C502a]   Drosophila melanogaster
FBal0257429 wds[HMS00746]   Drosophila melanogaster
FBal0043228 wds[j25]   Drosophila melanogaster
FBal0098145 wds[G0251]   Drosophila melanogaster
FBal0089154 wds[M30]   Drosophila melanogaster
FBal0089153 wds[M3]   Drosophila melanogaster
FBal0006809 wds[16]   Drosophila melanogaster
FBal0006814 wds[21]   Drosophila melanogaster
FBal0006805 wds[12]   Drosophila melanogaster
FBal0006817 wds[24]   Drosophila melanogaster
FBal0154359 wds[+t9]   Drosophila melanogaster
FBal0089151 wds[M67]   Drosophila melanogaster
FBal0006808 wds[15]   Drosophila melanogaster
FBal0006799 wds[6]   Drosophila melanogaster
FBal0006803 wds[10]   Drosophila melanogaster
FBal0006811 wds[18]   Drosophila melanogaster
FBal0006819 wds[26]   Drosophila melanogaster
FBal0006816 wds[23]   Drosophila melanogaster
FBal0006797 wds[4]   Drosophila melanogaster
FBal0006796 wds[3]   Drosophila melanogaster
FBal0006823 wds[30]   Drosophila melanogaster
FBal0006830 wds[37]   Drosophila melanogaster
FBal0006827 wds[34]   Drosophila melanogaster
FBal0006828 wds[35]   Drosophila melanogaster
FBal0006821 wds[28]   Drosophila melanogaster
FBal0006804 wds[11]   Drosophila melanogaster
FBal0006798 wds[5]   Drosophila melanogaster
FBal0006800 wds[7]   Drosophila melanogaster
FBal0089147 wds[T2]   Drosophila melanogaster
FBal0006824 wds[31]   Drosophila melanogaster

30 Clones

Secondary Identifier DB identifier
EC25446 FBcl0061273
EK255859 FBcl0062790
EK198311 FBcl0063356
EK254321 FBcl0063374
EK255037 FBcl0063532
EN11319 FBcl0090951
GH23515 FBcl0125441
LD05050 FBcl0159046
LD10938 FBcl0159150
LD05660 FBcl0159176
LD30385 FBcl0173876
LP13710 FBcl0187586
RE31658 FBcl0223423
RE22504 FBcl0223575
RE62954 FBcl0223818
RE08370 FBcl0223834
RE38206 FBcl0223852
RE27636 FBcl0223876
542779 FBcl0407030
Dmel_dig_013866_0665_2982 FBcl0364231
Dmel_neb_012422_0886_3245 FBcl0364232
Dmel_neb_012495_0408_3231 FBcl0364233
CK01.41B.C8 FBcl0456756
148877 FBcl0456729
148388 FBcl0456714
194103 FBcl0456692
70798 FBcl0456747
149947 FBcl0456750
118697 FBcl0456760
DPiM_RE31658 FBcl0739467

4 Exons

DB identifier Symbol
FBgn0040066:1 wds:1
FBgn0040066:2 wds:2
FBgn0040066:3 wds:3
FBgn0040066:4 wds:4

2 Transcripts

DB identifier Gene
FBtr0070438 wds
FBtr0308566 wds

4 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0070438-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0308566-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0070438-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0308566-3-prime-utr Drosophila melanogaster

Interactions

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Other

0 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
53428 NCBI Entrez Gene identifiers FBgn0040066
72718 BioGRID FBgn0040066

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0040066 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 997.0
FBgn0040066 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 804.0
FBgn0040066 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 800.0
FBgn0040066 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 932.0
FBgn0040066 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 868.0
FBgn0040066 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 810.0
FBgn0040066 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 458.0
FBgn0040066 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 973.0
FBgn0040066 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 522.0
FBgn0040066 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 639.0
FBgn0040066 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 902.0
FBgn0040066 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 589.0
FBgn0040066 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1047.0
FBgn0040066 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 811.0
FBgn0040066 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 932.0
FBgn0040066 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 875.0
FBgn0040066 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 855.0
FBgn0040066 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 912.0
FBgn0040066 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1084.0
FBgn0040066 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 690.0
FBgn0040066 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 1338.0
FBgn0040066 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 1037.0
FBgn0040066 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 775.0
FBgn0040066 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1180.0
FBgn0040066 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 778.0
FBgn0040066 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 2290.0
FBgn0040066 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 2075.0
FBgn0040066 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 1239.0
FBgn0040066 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1158.0
FBgn0040066 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1345.0

3 Introns

DB identifier
Organism . Name
intron_FBgn0040066:1_FBgn0040066:2 Drosophila melanogaster
intron_FBgn0040066:2_FBgn0040066:3 Drosophila melanogaster
intron_FBgn0040066:2_FBgn0040066:4 Drosophila melanogaster

35 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage wds none -0.048267546   19067489
Lipid storage wds none -0.703275661   19067489
Cell size and cell-cycle regulation (1) wds Decreased G1 DNA content sp   16496002
Cell size and cell-cycle regulation (1) wds none sp   16496002
Cell size and cell-cycle regulation (2) wds none 1.203   16496002
Cell size and cell-cycle regulation (3) wds none 455   16496002
Muscle morphogenesis and function (1) wds Lethal np   20220848
Muscle morphogenesis and function (1) wds none np   20220848
Muscle morphogenesis and function (2) wds Wing posture / locomotion / ability to fly defect or lethal / semi-lethal np   20220848
Heat nociception (1) wds Developmentally lethal -1.17   21074052
Heart development and function (1) wds none 0.75   20371351
Heart development and function (1) wds none 1   20371351
Serratia marcescens infection (1) wds none 0.519480519480519   19520911
Notch pathway regulation (4) wds Completely lethal (pupal) sp   19363474
Notch pathway regulation (4) wds none 0   19363474
G2-M DNA damage checkpoint regulation (2) wds Increased histone H3 phosphorylation with doxorubicin 43.58 with doxorubicin 21205937
G2-M DNA damage checkpoint regulation (2) wds Increased histone H3 phosphorylation with etoposide 33.1 with etoposide 21205937
G2-M DNA damage checkpoint regulation (2) wds Increased histone H3 phosphorylation after X-ray exposure 46.64 X-ray exposure 21205937
G2-M DNA damage checkpoint regulation (2) wds Increased histone H3 phosphorylation with bleocin 18.5 with bleocin 21205937
Self-renewal and differentiation in neural stem cells wds GFP aggregates number, GFP aggregates size, ganglion mother cell shorter lineages, neuroblast underproliferation, lethal sp   21549331
Adiposity regulation (1) wds none -0.574   20074523
Blood cell homeostasis regulation (1) wds Increased melanotic mass formation np   20540764
Blood cell homeostasis regulation (2) wds none np   20540764
Blood cell homeostasis regulation (3) wds none 0   20540764
Blood cell homeostasis regulation (4) wds none 0   20540764
Blood cell homeostasis regulation (5) wds Increased melanotic mass formation 52.4   20540764
Blood cell homeostasis regulation (6) wds none 4   20540764
Blood cell homeostasis regulation (7) wds none 0   20540764
Blood cell homeostasis regulation (8) wds Increased melanotic mass formation 43.4   20540764
RTK-Ras-ERK pathway regulation (1) wds none 0.01 0 minutes EGF stimulation 22028469

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