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Gene : Rpn12 D. melanogaster

DB identifier  ? FBgn0028693 Secondary Identifier  ? CG4157
Name  ? Regulatory particle non-ATPase 12 Source  FlyBase
  • synonyms:
  • FBgn0028693,
  • S14,
  • CG4157,
  • dRpn12,
  • FBan0004157,
  • Rpn12,
  • p30

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7 Alleles

DB identifier Symbol Allele Class Organism
FBal0181775 Rpn12[DG12110]   Drosophila melanogaster
FBal0257698 Rpn12[HMS01032]   Drosophila melanogaster
FBal0286658 Rpn12[Scer\UAS.ORF]   Drosophila melanogaster
FBal0134169 Rpn12[dsRNA.cWa]   Drosophila melanogaster
FBal0208408 Rpn12[GD11231]   Drosophila melanogaster
FBal0222218 Rpn12[NP2162]   Drosophila melanogaster
FBal0274113 Rpn12[NIG.4157R]   Drosophila melanogaster

44 Clones

Secondary Identifier DB identifier
DPiM_RE36854 FBcl0741522
UUGC0578 FBcl0005039
EK253442 FBcl0048146
EC40389 FBcl0062953
EC15076 FBcl0062957
GH28830 FBcl0107283
GM05076 FBcl0138773
GM08467 FBcl0138775
GM13291 FBcl0144621
GM30686 FBcl0144622
LD13866 FBcl0152511
LD22508 FBcl0165090
LD22333 FBcl0165097
LP09972 FBcl0180962
LP23569 FBcl0180968
RE10724 FBcl0197934
RE33445 FBcl0197957
RE16288 FBcl0197971
RE20607 FBcl0197978
RE52293 FBcl0197987
RE20501 FBcl0197997
RE34750 FBcl0198004
RE72992 FBcl0198016
RE36854 FBcl0198034
RE06040 FBcl0198039
RE03787 FBcl0198048
RE20978 FBcl0198053
RE16308 FBcl0198061
RH14960 FBcl0244950
RH13518 FBcl0244971

1 Exons

DB identifier Symbol
FBgn0028693:1 Rpn12:1

1 Transcripts

DB identifier Gene
FBtr0075308 Rpn12

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0075308-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0075308-3-prime-utr Drosophila melanogaster

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74 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
39845 NCBI Entrez Gene identifiers FBgn0028693
65148 BioGRID FBgn0028693

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0028693 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1556.0
FBgn0028693 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 1347.0
FBgn0028693 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 951.0
FBgn0028693 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1298.0
FBgn0028693 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1037.0
FBgn0028693 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 986.0
FBgn0028693 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 961.0
FBgn0028693 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 712.0
FBgn0028693 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 723.0
FBgn0028693 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1624.0
FBgn0028693 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1075.0
FBgn0028693 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 990.0
FBgn0028693 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 551.0
FBgn0028693 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 1051.0
FBgn0028693 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 1202.0
FBgn0028693 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 1141.0
FBgn0028693 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1004.0
FBgn0028693 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 745.0
FBgn0028693 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1303.0
FBgn0028693 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1023.0
FBgn0028693 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 859.0
FBgn0028693 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 1065.0
FBgn0028693 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 885.0
FBgn0028693 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 808.0
FBgn0028693 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 859.0
FBgn0028693 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 2636.0
FBgn0028693 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 3099.0
FBgn0028693 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 1730.0
FBgn0028693 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1034.0
FBgn0028693 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 987.0

0 Introns

24 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Rpn12 none 0.816284455   19067489
Lipid storage Rpn12 none 1.579477947   19067489
ERK signaling Rpn12 ERK activation reduced weak   17086199
Hedgehog signaling Rpn12 Decreased Hedgehog reporter activity -3.71   16311596
Constitutive protein secretion and Golgi organization (1) Rpn12 Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) Rpn12 none sp   16496002
Candida albicans phagocytosis (1) Rpn12 none np   16336044
Combinatorial effect with methyl methanesulphonate (2) Rpn12 none sp   19543366
Mutant human huntingtin aggregation Rpn12 Decreased mutant human huntingtin aggregation <= -2   19789644
Muscle morphogenesis and function (1) Rpn12 Lethal np   20220848
Heat nociception (1) Rpn12 Developmentally lethal -0.55   21074052
Heart development and function (1) Rpn12 none 1   20371351
Serratia marcescens infection (1) Rpn12 none -0.557377049180327   19520911
Notch pathway regulation (4) Rpn12 Completely lethal (before pupal) sp   19363474
PGN-induced dJNK phosphorylation Rpn12 Increased P-JNK protein expression with PGN 3.19 60 min PGN induction 19893628
Hh pathway regulation Rpn12 Downregulation of Hh pathway -0.253523642302067   17903264
Hh pathway regulation Rpn12 none -0.0138372536175038   17903264
Self-renewal and differentiation in neural stem cells Rpn12 GFP aggregates number, GFP aggregates size, neuroblast larger cell size, neuroblast cell shape, ganglion mother cell larger cell size, ganglion mother cell shorter lineages, ganglion mother cell shape, neuroblast underproliferation, lethal sp   21549331
Adiposity regulation (1) Rpn12 none -0.963   20074523
RTK-Ras-ERK pathway regulation (1) Rpn12 Decreased ERK phosphorylation after EGF stimulation -1.93 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) Rpn12 Decreased ERK phosphorylation after EGF stimulation -2.82 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Rpn12 none 1.39 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Rpn12 Decreased ERK phosphorylation after sSpitz and EGF stimulation -2.64 30 minutes sSpitz stimulation 22028469
Glycosylation regulation (1) Rpn12 none sp   21203496

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