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Gene : Cct1 D. melanogaster

DB identifier  ? FBgn0041342 Secondary Identifier  ? CG1049
Name  ? CTP:phosphocholine cytidylyltransferase 1 Source  FlyBase
  • synonyms:
  • FBan0001049,
  • cytidylyltransferase 1,
  • Cct,
  • CCT1,
  • CTP:phosphocholine cytidylyltransferase,
  • CG1049,
  • FBgn0041342,
  • CT41283,
  • FBgn0035230,
  • Phosphocholine cytidylyltransferase

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40 Alleles

DB identifier Symbol Allele Class Organism
FBal0211907 Cct1[CB02171]   Drosophila melanogaster
FBal0184376 Cct1[DG23712]   Drosophila melanogaster
FBal0184372 Cct1[d08531]   Drosophila melanogaster
FBal0184373 Cct1[d07077]   Drosophila melanogaster
FBal0260382 Cct1[MI02624]   Drosophila melanogaster
FBal0184374 Cct1[d01834]   Drosophila melanogaster
FBal0184375 Cct1[c05866]   Drosophila melanogaster
FBal0156788 Cct1[BN81] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0131726 Cct1[EP3346]   Drosophila melanogaster
FBal0152682 Cct1[16919] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0131725 Cct1[EP3379]   Drosophila melanogaster
FBal0145138 Cct1[PdL8R128]   Drosophila melanogaster
FBal0131724 Cct1[EP831] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0148112 Cct1[EY00264]   Drosophila melanogaster
FBal0148111 Cct1[KG04899]   Drosophila melanogaster
FBal0270494 Cct1[NIG.1049R]   Drosophila melanogaster
FBal0156789 Cct1[99]   Drosophila melanogaster
FBal0156794 Cct1[+t11.194]   Drosophila melanogaster
FBal0156793 Cct1[124]   Drosophila melanogaster
FBal0156787 Cct1[unspecified]   Drosophila melanogaster
FBal0156792 Cct1[179] loss of function allele Drosophila melanogaster
FBal0156791 Cct1[244]   Drosophila melanogaster
FBal0184378 Cct1[16919rv8] wild-type allele Drosophila melanogaster
FBal0156790 Cct1[299] loss of function allele Drosophila melanogaster
FBal0184377 Cct1[Ala.Scer\UAS] antimorphic allele - genetic evidence Drosophila melanogaster
FBal0184379 Cct1[+t11.2]   Drosophila melanogaster
FBal0206536 Cct1[GD6991]   Drosophila melanogaster
FBal0223808 Cct1[CB-0122-3]   Drosophila melanogaster
FBal0223809 Cct1[c03632]   Drosophila melanogaster
FBal0223810 Cct1[CB-0748-3]   Drosophila melanogaster

129 Clones

Secondary Identifier DB identifier
EK192557 FBcl0029010
EK256225 FBcl0029154
EK070439 FBcl0029298
EK263401 FBcl0029450
EK292340 FBcl0029510
EK121230 FBcl0029530
EK248426 FBcl0029626
EK160803 FBcl0029646
EK295026 FBcl0029666
EK186848 FBcl0029686
EK166142 FBcl0029798
EK271227 FBcl0029814
EP21727 FBcl0076063
EP07156 FBcl0076089
EP21107 FBcl0082393
EP21854 FBcl0082401
EN00749 FBcl0092221
EN00630 FBcl0092279
GH26590 FBcl0133453
GH05187 FBcl0133473
GH21561 FBcl0133501
HL03306 FBcl0150616
LD12556 FBcl0161900
LD03414 FBcl0161910
LD02465 FBcl0161915
LD31875 FBcl0177466
LD34758 FBcl0177488
LD38581 FBcl0177493
LD34141 FBcl0177495
LD46058 FBcl0177498

8 Exons

DB identifier Symbol
FBgn0041342:1 Cct1:1
FBgn0041342:6 Cct1:6
FBgn0041342:7 Cct1:7
FBgn0041342:8 Cct1:8
FBgn0041342:3 Cct1:3
FBgn0041342:4 Cct1:4
FBgn0041342:5 Cct1:5
FBgn0041342:2 Cct1:2

5 Transcripts

DB identifier Gene
FBtr0333396 Cct1
FBtr0072738 Cct1
FBtr0072740 Cct1
FBtr0072741 Cct1
FBtr0072739 Cct1

10 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0072738-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0072739-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0072740-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0072741-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0333396-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0072738-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0072739-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0072740-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0072741-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0333396-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
117353 NCBI Entrez Gene identifiers FBgn0041342
72882 BioGRID FBgn0041342

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0041342 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 2174.0
FBgn0041342 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 1559.0
FBgn0041342 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1330.0
FBgn0041342 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 2260.0
FBgn0041342 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1513.0
FBgn0041342 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 1680.0
FBgn0041342 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 2364.0
FBgn0041342 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 3024.0
FBgn0041342 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 2035.0
FBgn0041342 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1486.0
FBgn0041342 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1248.0
FBgn0041342 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 1035.0
FBgn0041342 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1544.0
FBgn0041342 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 870.0
FBgn0041342 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 2381.0
FBgn0041342 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 1438.0
FBgn0041342 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1548.0
FBgn0041342 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1954.0
FBgn0041342 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1087.0
FBgn0041342 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 865.0
FBgn0041342 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 1933.0
FBgn0041342 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 1682.0
FBgn0041342 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 2145.0
FBgn0041342 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 2240.0
FBgn0041342 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 2414.0
FBgn0041342 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 1088.0
FBgn0041342 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 1273.0
FBgn0041342 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 1063.0
FBgn0041342 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1001.0
FBgn0041342 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 761.0

8 Introns

DB identifier
Organism . Name
intron_FBgn0041342:1_FBgn0041342:6 Drosophila melanogaster
intron_FBgn0041342:6_FBgn0041342:7 Drosophila melanogaster
intron_FBgn0041342:7_FBgn0041342:8 Drosophila melanogaster
intron_FBgn0041342:3_FBgn0041342:6 Drosophila melanogaster
intron_FBgn0041342:4_FBgn0041342:6 Drosophila melanogaster
intron_FBgn0041342:5_FBgn0041342:6 Drosophila melanogaster
intron_FBgn0041342:1_FBgn0041342:2 Drosophila melanogaster
intron_FBgn0041342:2_FBgn0041342:6 Drosophila melanogaster

19 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Cct1 none -1.623815186   19067489
Lipid storage Cct1 none 1.073338348   19067489
ERK signaling Cct1 ERK activation reduced weak   17086199
Imd pathway regulation Cct1 Decreased Dipt::lacZ protein expression after lipopolysaccharide stimulation 4   15221030
Cell size and cell-cycle regulation (1) Cct1 none sp   16496002
Lipid storage Cct1 Fewer lipid droplets, larger size strong   18408709
Muscle morphogenesis and function (1) Cct1 none np   20220848
Muscle morphogenesis and function (1) Cct1 none np   20220848
Heart development and function (1) Cct1 none 1   20371351
Serratia marcescens infection (1) Cct1 none -0.0384615384615384   19520911
Notch pathway regulation (4) Cct1 none 0   19363474
Notch pathway regulation (4) Cct1 none 0   19363474
Adiposity regulation (1) Cct1 none -0.34   20074523
RTK-Ras-ERK pathway regulation (1) Cct1 none -0.36 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) Cct1 none -0.71 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Cct1 none -0.39 30 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Cct1 none -0.28 10 minutes sSpitz stimulation 22028469
Hippo pathway regulation Cct1 none -1.98   23263283
Glycosylation regulation (1) Cct1 none sp   21203496

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