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Gene : zetaCOP D. melanogaster
DB identifier  ? FBgn0040512 Secondary Identifier  ? CG3948
Name  ? zetaCOP Source  FlyBase
  • synonyms:
  • FBgn0036651,
  • FBan0003948,
  • copz1,
  • CG3948,
  • FBgn0040512,
  • COPI zeta subunit,
  • zetaCOP,
  • zeta-Cop,
  • CT13124
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5 Alleles

DB identifier Symbol Allele Class Organism
FBal0240300 zetaCOP[HM05171]   Drosophila melanogaster
FBal0162867 zetaCOP[e00020]   Drosophila melanogaster
FBal0198578 zetaCOP[GD11168]   Drosophila melanogaster
FBal0235547 zetaCOP[KK108399]   Drosophila melanogaster
FBal0274032 zetaCOP[NIG.3948R]   Drosophila melanogaster

128 Clones

Secondary Identifier DB identifier
DPiM_RE70427 FBcl0741143
EK298636 FBcl0037812
EK208003 FBcl0045482
EK044837 FBcl0046796
EK207243 FBcl0047448
EK212506 FBcl0047544
EK160124 FBcl0047572
EK086647 FBcl0047624
EK184608 FBcl0047688
EK084917 FBcl0047752
EK281607 FBcl0047858
EK074257 FBcl0047916
bs45c03 FBcl0048165
EC14876 FBcl0062471
EC14919 FBcl0062539
EC22022 FBcl0062555
EC40081 FBcl0062557
EC00804 FBcl0062613
EP12525 FBcl0075695
EN09653 FBcl0092045
GH06649 FBcl0107045
RE21602 FBcl0197546
RE03169 FBcl0197552
RE38606 FBcl0197581
RE70427 FBcl0197604
SD12056 FBcl0277563
SD15365 FBcl0277601
SD16054 FBcl0277672
FGC013F09 FBcl0385211
FGH114F02 FBcl0387637

6 Exons

DB identifier Symbol
FBgn0040512:5 zetaCOP:5
FBgn0040512:4 zetaCOP:4
FBgn0040512:3 zetaCOP:3
FBgn0040512:1 zetaCOP:1
FBgn0040512:6 zetaCOP:6
FBgn0040512:2 zetaCOP:2

3 Transcripts

DB identifier Gene
FBtr0075353 zetaCOP
FBtr0075352 zetaCOP
FBtr0075351 zetaCOP

6 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0075352-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0075351-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0075353-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0075352-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0075351-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0075353-3-prime-utr Drosophila melanogaster

Interactions

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Other

7 Pathways

2 Cross References

Identifier
Source . Name
Subject . Primary Identifier
39862 NCBI Entrez Gene identifiers FBgn0040512
65161 BioGRID FBgn0040512

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier
Submission . Title
Cell Line . Name
Developmental Stage . Name 		Score
FBgn0040512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 3772.0
FBgn0040512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 4422.0
FBgn0040512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1652.0
FBgn0040512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 2680.0
FBgn0040512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 2511.0
FBgn0040512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 1781.0
FBgn0040512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 1731.0
FBgn0040512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 2553.0
FBgn0040512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 2942.0
FBgn0040512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1586.0
FBgn0040512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 2063.0
FBgn0040512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 1549.0
FBgn0040512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1595.0
FBgn0040512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 1598.0
FBgn0040512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 1494.0
FBgn0040512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 1872.0
FBgn0040512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1742.0
FBgn0040512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1863.0
FBgn0040512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 2776.0
FBgn0040512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1946.0
FBgn0040512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 1868.0
FBgn0040512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 2710.0
FBgn0040512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 1441.0
FBgn0040512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 2077.0
FBgn0040512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1534.0
FBgn0040512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 1309.0
FBgn0040512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 738.0
FBgn0040512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 476.0
FBgn0040512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1175.0
FBgn0040512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1657.0

5 Introns

DB identifier
Organism . Name
intron_FBgn0040512:5_FBgn0040512:4 Drosophila melanogaster
intron_FBgn0040512:4_FBgn0040512:2 Drosophila melanogaster
intron_FBgn0040512:4_FBgn0040512:3 Drosophila melanogaster
intron_FBgn0040512:3_FBgn0040512:1 Drosophila melanogaster
intron_FBgn0040512:6_FBgn0040512:4 Drosophila melanogaster

37 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage zetaCOP Increased lipid droplet area 10.1035206   19067489
Lipid storage zetaCOP Increased lipid droplet area 12.13983056   19067489
Caspase activation in apoptosis (1) - combinatorial effect with doxorubicin zetaCOP Increased viability with doxorubicin np   17998402
Caspase activation in apoptosis (2) - combinatorial effect with doxorubicin zetaCOP Decreased caspase-3/7-like activity with doxorubicin np   17998402
Chlamydia caviae infection zetaCOP Decreased Chlamydia caviae infection np   17967059
Drosophila C virus infection zetaCOP Drosophila C virus replication down np   17040126
Cytokinesis regulation zetaCOP Binucleate cells with decreased viability weak   15547975
Intracellular Listeria monocytogenes infection zetaCOP Decreased GFP protein expression strong   16020693
L. monocytogenes infection zetaCOP Fewer infected cells, less vacuolar escape ***   16157870
Hedgehog signaling zetaCOP Decreased Hedgehog reporter activity -2.73   16311596
Mycobacterial infection (1) - M. fortuitum infection zetaCOP Decreased M. fortuitum intracellular infection 4.9 measurement after 3 days 16020694
Mycobacterial infection (2) - E. coli phagocytosis zetaCOP Decreased E. coli phagocytosis np   16020694
Constitutive protein secretion and Golgi organization (1) zetaCOP Decreased horseradish peroxidase protein expression sp   16452979
Constitutive protein secretion and Golgi organization (2) zetaCOP Fused Golgi membranes with endoplasmic reticulum np   16452979
Candida albicans phagocytosis (1) zetaCOP Decreased Candida albicans phagocytosis np   16336044
Candida albicans phagocytosis (2) zetaCOP Decreased Escherichia coli phagocytosis 42   16336044
Candida albicans phagocytosis (3) zetaCOP Decreased latex beads phagocytosis 35   16336044
Brucella melitensis infection zetaCOP Decreased viability np   18654626
Lipid storage zetaCOP Normal/larger sized lipid droplets, more dispersed strong   18408709
Mutant human huntingtin aggregation zetaCOP Decreased mutant human huntingtin aggregation <= -2   19789644
Muscle morphogenesis and function (1) zetaCOP Lethal np   20220848
Muscle morphogenesis and function (2) zetaCOP Wing posture / locomotion / ability to fly defect or lethal / semi-lethal np   20220848
Heart development and function (1) zetaCOP Embryonic lethal or no offspring 0   20371351
Serratia marcescens infection (1) zetaCOP Decreased viability after Serratia marcescens infection -1.67532467532467   19520911
Notch pathway regulation (4) zetaCOP Completely lethal (before pupal) sp   19363474
Akt-TOR pathway negative feedback regulation zetaCOP none -2.2 10 min insulin stimulation 20585550
Hh pathway regulation zetaCOP Downregulation of Hh pathway -0.296687064610042   17903264
Hh pathway regulation zetaCOP none -0.227140246565357   17903264
Adiposity regulation (1) zetaCOP none -0.62   20074523
Secretory pathway regulation zetaCOP Decreased BiP signal peptide and firefly luciferase fusion protein expression (-2) - (-1.5)   19942856

0 Submissions





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