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Gene : Spt6 D. melanogaster

DB identifier  ? FBgn0028982 Secondary Identifier  ? CG12225
Name  ? Spt6 Source  FlyBase
  • synonyms:
  • FBgn0026691,
  • Dspt6,
  • FBgn0028682,
  • FBan0012225,
  • l(1)G0063,
  • CG12225,
  • spt 6,
  • SPT6,
  • FBgn0028982

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12 Alleles

DB identifier Symbol Allele Class Organism
FBal0211740 Spt6[CA07692]   Drosophila melanogaster
FBal0096837 Spt6[G0063]   Drosophila melanogaster
FBal0130592 Spt6[PL83]   Drosophila melanogaster
FBal0248129 Spt6[HMS00364]   Drosophila melanogaster
FBal0141373 Spt6[Act5C.T:Zzzz\FLAG,T:Zzzz\His6]   Drosophila melanogaster
FBal0193725 Spt6[B1-26]   Drosophila melanogaster
FBal0193728 Spt6[D1-10]   Drosophila melanogaster
FBal0287486 Spt6[Scer\UAS.ORF.T:Ivir\HA1]   Drosophila melanogaster
FBal0208612 Spt6[GD7536]   Drosophila melanogaster
FBal0271174 Spt6[NIG.12225R]   Drosophila melanogaster
FBal0279882 Spt6[dsRNA.Scer\UAS.WIZ]   Drosophila melanogaster
FBal0279883 Spt6[Scer\UAS.T:Avic\GFP-YFP]   Drosophila melanogaster

82 Clones

Secondary Identifier DB identifier
EK112638 FBcl0081294
EK112634 FBcl0081470
EK227208 FBcl0081590
EK243354 FBcl0081634
EK110656 FBcl0081652
EK113749 FBcl0081766
EK072929 FBcl0083520
EK170941 FBcl0083536
EK004815 FBcl0083732
EK067849 FBcl0084708
EK002605 FBcl0085102
EK000913 FBcl0085336
EK070332 FBcl0085482
EK081012 FBcl0086418
GM02265 FBcl0142181
GM10781 FBcl0142200
GM06618 FBcl0142217
GM02667 FBcl0142224
GM25118 FBcl0146868
GM21095 FBcl0146882
LD20322 FBcl0151304
LD20753 FBcl0151325
LD04335 FBcl0151376
LD17704 FBcl0151467
LD02327 FBcl0159579
LD11553 FBcl0159602
LD17816 FBcl0159631
LD03201 FBcl0159702
LD11061 FBcl0160134
LD17780 FBcl0160138

7 Exons

DB identifier Symbol
FBgn0028982:1 Spt6:1
FBgn0028982:2 Spt6:2
FBgn0028982:3 Spt6:3
FBgn0028982:4 Spt6:4
FBgn0028982:5 Spt6:5
FBgn0028982:7 Spt6:7
FBgn0028982:6 Spt6:6

2 Transcripts

DB identifier Gene
FBtr0070896 Spt6
FBtr0340027 Spt6

4 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0070896-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0340027-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0070896-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0340027-3-prime-utr Drosophila melanogaster

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0 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
44000 NCBI Entrez Gene identifiers FBgn0028982
68765 BioGRID FBgn0028982

10 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0028982 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1232.0
FBgn0028982 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 1158.0
FBgn0028982 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1261.0
FBgn0028982 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1394.0
FBgn0028982 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1105.0
FBgn0028982 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 827.0
FBgn0028982 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 1531.0
FBgn0028982 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 1381.0
FBgn0028982 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 727.0
FBgn0028982 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1528.0
FBgn0028982 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1666.0
FBgn0028982 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 948.0
FBgn0028982 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1270.0
FBgn0028982 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 1304.0
FBgn0028982 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 1181.0
FBgn0028982 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 903.0
FBgn0028982 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1501.0
FBgn0028982 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1027.0
FBgn0028982 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1644.0
FBgn0028982 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1629.0
FBgn0028982 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 1491.0
FBgn0028982 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 1153.0
FBgn0028982 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 1371.0
FBgn0028982 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1067.0
FBgn0028982 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1218.0
FBgn0028982 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 2873.0
FBgn0028982 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 2906.0
FBgn0028982 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 3403.0
FBgn0028982 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 2175.0
FBgn0028982 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1498.0

6 Introns

DB identifier
Organism . Name
intron_FBgn0028982:1_FBgn0028982:2 Drosophila melanogaster
intron_FBgn0028982:2_FBgn0028982:3 Drosophila melanogaster
intron_FBgn0028982:3_FBgn0028982:4 Drosophila melanogaster
intron_FBgn0028982:4_FBgn0028982:5 Drosophila melanogaster
intron_FBgn0028982:5_FBgn0028982:7 Drosophila melanogaster
intron_FBgn0028982:5_FBgn0028982:6 Drosophila melanogaster

39 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Spt6 Decreased lipid droplet area -3.00654445   19067489
Lipid storage Spt6 Decreased lipid droplet area -5.137289279   19067489
Lipid storage Spt6 Decreased lipid droplet area -1.869489985   19067489
Lipid storage Spt6 Decreased lipid droplet area -0.55868646   19067489
Chlamydia caviae infection Spt6 Decreased Chlamydia caviae infection np   17967059
ERK signaling Spt6 ERK activation increased strong   17086199
Intracellular Listeria monocytogenes infection Spt6 Decreased GFP protein expression strong   16020693
Innate immunity Spt6 Decreased IMD/Rel reporter activity -5   16170305
Constitutive protein secretion and Golgi organization (1) Spt6 Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) Spt6 Increased G1 DNA content sp   16496002
Cell size and cell-cycle regulation (2) Spt6 none 1.249   16496002
Cell size and cell-cycle regulation (3) Spt6 none 465   16496002
Candida albicans phagocytosis (1) Spt6 none np   16336044
Dendrite pattern formation Spt6 none np   16547170
Muscle morphogenesis and function (1) Spt6 Lethal np   20220848
Muscle morphogenesis and function (1) Spt6 Lethal np   20220848
Regulated secretory pathway biogenesis (1) Spt6 none -1.7   21149569
Heart development and function (1) Spt6 Embryonic lethal or no offspring 0   20371351
Heart development and function (1) Spt6 Embryonic lethal or no offspring 0   20371351
Serratia marcescens infection (1) Spt6 none 0.720930232558139   19520911
Notch pathway regulation (4) Spt6 Completely lethal (before pupal) sp   19363474
Notch pathway regulation (4) Spt6 Completely lethal (before pupal) sp   19363474
PGN-induced dJNK phosphorylation Spt6 Increased P-JNK protein expression with PGN 4.58 60 min PGN induction 19893628
Pol II elongation Spt6 Decreased Hsp70 mRNA expression 57 20 min heat shock 19279664
Adiposity regulation (1) Spt6 none -0.75   20074523
Blood cell homeostasis regulation (1) Spt6 Increased melanotic mass formation np   20540764
Blood cell homeostasis regulation (2) Spt6 none np   20540764
Blood cell homeostasis regulation (3) Spt6 Increased melanotic mass formation 32.1   20540764
Blood cell homeostasis regulation (4) Spt6 none 1.4   20540764
Blood cell homeostasis regulation (5) Spt6 Increased melanotic mass formation 41.4   20540764

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