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Gene : CG3523 D. melanogaster

DB identifier  ? FBgn0027571 Secondary Identifier  ? CG3523
Source  FlyBase
  • synonyms:
  • FBgn0027571,
  • dFAS,
  • Fatty acid synthetase,
  • FBgn0044793,
  • anon-EST:Posey235,
  • anon-WO0138581.1,
  • FAS[CG3523],
  • FBgn0027682,
  • FBan0003523,
  • Fatty Acid Synthase,
  • FAS,
  • FBgn0027719,
  • BcDNA:GH07626,
  • DM_7295848,
  • anon-EST:Posey43

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16 Alleles

DB identifier Symbol Allele Class Organism
FBal0240270 CG3523[HM05141]   Drosophila melanogaster
FBal0185778 CG3523[d06961]   Drosophila melanogaster
FBal0185779 CG3523[d04847]   Drosophila melanogaster
FBal0185777 CG3523[f05657]   Drosophila melanogaster
FBal0131767 CG3523[KG03696]   Drosophila melanogaster
FBal0268924 CG3523[NIG.3523R]   Drosophila melanogaster
FBal0136138 CG3523[dsRNA.cRa]   Drosophila melanogaster
FBal0263428 CG3523[HMS01524]   Drosophila melanogaster
FBal0203970 CG3523[GD14739]   Drosophila melanogaster
FBal0214082 CG3523[GD17144]   Drosophila melanogaster
FBal0225108 CG3523[NP0870]   Drosophila melanogaster
FBal0225109 CG3523[NP5166]   Drosophila melanogaster
FBal0225110 CG3523[SH2254]   Drosophila melanogaster
FBal0225111 CG3523[5-HA-2771]   Drosophila melanogaster
FBal0225112 CG3523[d02216]   Drosophila melanogaster
FBal0234870 CG3523[KK107330]   Drosophila melanogaster

114 Clones

Secondary Identifier DB identifier
AF171846 FBcl0000229
EP21452 FBcl0073741
EN07139 FBcl0090223
EN03827 FBcl0090225
EN13811 FBcl0090227
EN09044 FBcl0090265
EN12928 FBcl0090269
EK143606 FBcl0107324
EK198120 FBcl0107338
EK151236 FBcl0107368
EK293549 FBcl0107852
EK122625 FBcl0107856
EK213834 FBcl0107864
EK124317 FBcl0107870
EK163011 FBcl0107874
EK089806 FBcl0107896
EK069031 FBcl0107922
EK140426 FBcl0108122
EK264962 FBcl0108148
EK076354 FBcl0108152
GH17723 FBcl0132237
GH06939 FBcl0132539
GH24695 FBcl0132585
GH05332 FBcl0133095
GH05642 FBcl0133241
GH22808 FBcl0133337
GH03692 FBcl0133991
GH10407 FBcl0134403
GH07626 FBcl0134497
GH22015 FBcl0134503

7 Exons

DB identifier Symbol
FBgn0027571:1 CG3523:1
FBgn0027571:3 CG3523:3
FBgn0027571:4 CG3523:4
FBgn0027571:5 CG3523:5
FBgn0027571:6 CG3523:6
FBgn0027571:7 CG3523:7
FBgn0027571:2 CG3523:2

2 Transcripts

DB identifier Gene
FBtr0077659 CG3523
FBtr0335387 CG3523

4 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0077659-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0335387-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0077659-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0335387-3-prime-utr Drosophila melanogaster

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46 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
33524 NCBI Entrez Gene identifiers FBgn0027571
59741 BioGRID FBgn0027571

10 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0027571 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 7288.0
FBgn0027571 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 8623.0
FBgn0027571 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 8679.0
FBgn0027571 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 16135.0
FBgn0027571 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 4821.0
FBgn0027571 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 6091.0
FBgn0027571 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 10549.0
FBgn0027571 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 15373.0
FBgn0027571 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 4116.0
FBgn0027571 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 8610.0
FBgn0027571 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 10664.0
FBgn0027571 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 7122.0
FBgn0027571 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 7151.0
FBgn0027571 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 6364.0
FBgn0027571 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 15177.0
FBgn0027571 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 8318.0
FBgn0027571 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 10335.0
FBgn0027571 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 9556.0
FBgn0027571 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 5467.0
FBgn0027571 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 8230.0
FBgn0027571 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 12895.0
FBgn0027571 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 9828.0
FBgn0027571 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 7798.0
FBgn0027571 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 6110.0
FBgn0027571 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 5978.0
FBgn0027571 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 515.0
FBgn0027571 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 264.0
FBgn0027571 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 247.0
FBgn0027571 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 137.0
FBgn0027571 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 232.0

6 Introns

DB identifier
Organism . Name
intron_FBgn0027571:1_FBgn0027571:3 Drosophila melanogaster
intron_FBgn0027571:3_FBgn0027571:4 Drosophila melanogaster
intron_FBgn0027571:4_FBgn0027571:5 Drosophila melanogaster
intron_FBgn0027571:5_FBgn0027571:6 Drosophila melanogaster
intron_FBgn0027571:6_FBgn0027571:7 Drosophila melanogaster
intron_FBgn0027571:2_FBgn0027571:3 Drosophila melanogaster

30 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage CG3523 none -0.135570185   19067489
Lipid storage CG3523 none -1.438357628   19067489
Chlamydia caviae infection CG3523 Decreased Chlamydia caviae infection np   17967059
ERK signaling CG3523 ERK activation increased weak   17086199
Drosophila C virus infection CG3523 Drosophila C virus replication down np   17040126
E. coli / S. aureus infection CG3523 Cell death np   11912489
Intracellular Listeria monocytogenes infection CG3523 Decreased GFP protein expression strong   16020693
Mycobacterial infection (1) - M. fortuitum infection CG3523 Decreased M. fortuitum intracellular infection 11.4 measurement after 3 days 16020694
Mycobacterial infection (2) - E. coli phagocytosis CG3523 Decreased E. coli phagocytosis np   16020694
Constitutive protein secretion and Golgi organization (1) CG3523 Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) CG3523 none sp   16496002
Mitochondrial biogenesis and function CG3523 Decreased mitochondrial citrate synthase activity 0.612   18042644
Lipid storage CG3523 Fewer lipid droplets, larger size strong   18408709
Muscle morphogenesis and function (1) CG3523 none np   20220848
Heart development and function (1) CG3523 none 1   20371351
Serratia marcescens infection (1) CG3523 none 0.462686567164179   19520911
Notch pathway regulation (4) CG3523 none 0   19363474
Adiposity regulation (1) CG3523 Decreased triglyceride expression -0.62   20074523
Adiposity regulation (2) CG3523 none 0.022   20074523
Adiposity regulation (3) CG3523 none 0.165   20074523
Adiposity regulation (4) CG3523 Increased triglyceride expression 0.663   20074523
Adiposity regulation (5) CG3523 Decreased triglyceride expression -0.645   20074523
RTK-Ras-ERK pathway regulation (1) CG3523 none 1.07 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) CG3523 Decreased ERK phosphorylation after EGF stimulation -3.69 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) CG3523 none 0.2 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) CG3523 none -0.96 30 minutes sSpitz stimulation 22028469
Wg pathway regulation (1) CG3523 Decreased WgRluc and not changed sFluc protein expression medium   21886182
Hippo pathway regulation CG3523 none 2.32   23263283
Glycosylation regulation (1) CG3523 Decreased alpha1,3-fucose Chp glycosylation, decreased alpha1,6-fucose Chp glycosylation, decreased (GlcNAc)n Chp glycosylation, decreased mannose Chp glycosylation sp   21203496
Glycosylation regulation (2) CG3523 none np   21203496

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