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Gene : UbcD6 D. melanogaster

DB identifier  ? FBgn0004436 Secondary Identifier  ? CG2013
Name  ? Ubiquitin conjugating enzyme Source  FlyBase
  • synonyms:
  • dRAD6,
  • FBgn0004436,
  • Dhr6,
  • FBgn0064873,
  • BcDNA:RE56673,
  • CG2013,
  • Ubiquitin Conjugating Enzyme,
  • FBan0002013,
  • Rad6a,
  • RAD6,
  • UbcD6

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14 Alleles

DB identifier Symbol Allele Class Organism
FBal0281477 UbcD6[HMS02466]   Drosophila melanogaster
FBal0260324 UbcD6[MI02360]   Drosophila melanogaster
FBal0155722 UbcD6[EY04634] hypomorphic allele - molecular evidence Drosophila melanogaster
FBal0181108 UbcD6[d01923]   Drosophila melanogaster
FBal0181107 UbcD6[e01465]   Drosophila melanogaster
FBal0280431 UbcD6[dsRNA.Scer\UAS]   Drosophila melanogaster
FBal0192846 UbcD6[MB00268]   Drosophila melanogaster
FBal0288690 UbcD6[Delta1] hypomorphic allele - molecular evidence Drosophila melanogaster
FBal0288691 UbcD6[+tHa]   Drosophila melanogaster
FBal0262871 UbcD6[GL00405]   Drosophila melanogaster
FBal0208911 UbcD6[GD13294]   Drosophila melanogaster
FBal0208912 UbcD6[GD17232]   Drosophila melanogaster
FBal0230030 UbcD6[CB-5152-3]   Drosophila melanogaster
FBal0230031 UbcD6[5-HA-1292]   Drosophila melanogaster

93 Clones

Secondary Identifier DB identifier
ESG0113a.B21_G10 FBcl0002183
EK225307 FBcl0050892
EK144628 FBcl0050904
EK012849 FBcl0051458
EK160117 FBcl0051470
EK231716 FBcl0051482
EK041737 FBcl0051530
EK116044 FBcl0051544
EK255130 FBcl0051554
EK144820 FBcl0051572
EK257003 FBcl0051576
EK062557 FBcl0051592
EK139503 FBcl0051602
EK170856 FBcl0051614
EK103319 FBcl0051620
EK121906 FBcl0051630
EK266106 FBcl0051636
EK259641 FBcl0051652
EK199502 FBcl0051656
EK264056 FBcl0051664
EK207903 FBcl0051688
EK146718 FBcl0051748
EK149212 FBcl0051762
EK015239 FBcl0051776
EK301817 FBcl0051792
EK259033 FBcl0051800
EC03136 FBcl0062215
EC28568 FBcl0062223
EC02936 FBcl0062225
EP00423 FBcl0075453

4 Exons

DB identifier Symbol
FBgn0004436:4 UbcD6:4
FBgn0004436:3 UbcD6:3
FBgn0004436:1 UbcD6:1
FBgn0004436:2 UbcD6:2

2 Transcripts

DB identifier Gene
FBtr0306106 UbcD6
FBtr0078849 UbcD6

4 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0078849-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0306106-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0078849-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0306106-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
40610 NCBI Entrez Gene identifiers FBgn0004436
65824 BioGRID FBgn0004436

10 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0004436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1913.0
FBgn0004436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 1692.0
FBgn0004436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 2339.0
FBgn0004436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1645.0
FBgn0004436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1933.0
FBgn0004436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 2397.0
FBgn0004436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 3012.0
FBgn0004436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 2495.0
FBgn0004436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 2643.0
FBgn0004436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 2952.0
FBgn0004436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 3455.0
FBgn0004436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 1592.0
FBgn0004436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 2615.0
FBgn0004436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 1779.0
FBgn0004436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 2717.0
FBgn0004436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 3337.0
FBgn0004436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 3689.0
FBgn0004436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 2144.0
FBgn0004436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1985.0
FBgn0004436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 2581.0
FBgn0004436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 2689.0
FBgn0004436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 1682.0
FBgn0004436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 2839.0
FBgn0004436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 3504.0
FBgn0004436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 2129.0
FBgn0004436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 3282.0
FBgn0004436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 2942.0
FBgn0004436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 1396.0
FBgn0004436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1289.0
FBgn0004436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1455.0

3 Introns

DB identifier
Organism . Name
intron_FBgn0004436:4_FBgn0004436:3 Drosophila melanogaster
intron_FBgn0004436:3_FBgn0004436:2 Drosophila melanogaster
intron_FBgn0004436:3_FBgn0004436:1 Drosophila melanogaster

34 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage UbcD6 none -2.937169569   19067489
Lipid storage UbcD6 none 0.418481971   19067489
ERK signaling UbcD6 ERK activation increased weak   17086199
Hedgehog signaling UbcD6 Decreased Hedgehog reporter activity -3.75   16311596
Mitosis UbcD6 Monastral bipolar spindle np   17412918
Centriole duplication and centrosome maturation UbcD6 Centrosome separation defect np   18798690
Muscle morphogenesis and function (1) UbcD6 Flightless np   20220848
Muscle morphogenesis and function (1) UbcD6 Lethal np   20220848
Muscle morphogenesis and function (1) UbcD6 Lethal np   20220848
Muscle morphogenesis and function (4) UbcD6 Missing indirect flight muscles, degenerate myofibrils, fuzzy (broadened) Z-line np   20220848
Heat nociception (1) UbcD6 none -0.25   21074052
Heat nociception (1) UbcD6 none 0.98   21074052
Heart development and function (1) UbcD6 none 1   20371351
Serratia marcescens infection (1) UbcD6 none -1.27397260273972   19520911
Serratia marcescens infection (1) UbcD6 none 0.388235294117647   19520911
Notch pathway regulation (4) UbcD6 Completely lethal (pupal) sp   19363474
Notch pathway regulation (4) UbcD6 Completely lethal (pupal) sp   19363474
Notch pathway regulation (4) UbcD6 Completely lethal (pupal) sp   19363474
PGN-induced dJNK phosphorylation UbcD6 Increased P-JNK protein expression with PGN 2.48 15 min PGN induction 19893628
Hh pathway regulation UbcD6 Downregulation of Hh pathway -0.303292413400131   17903264
Hh pathway regulation UbcD6 none 0.174496410006756   17903264
Pol II elongation UbcD6 Decreased Hsp70 mRNA expression 44 20 min heat shock 19279664
Notch pathway regulation (1) UbcD6 Upregulation of Notch pathway np   20493818
Notch pathway regulation (2) UbcD6 Upregulation of Notch pathway; delay of larval development; wing disc size: overgrown; wing disc NRE:EGFP: up;lethal sp en-GAL4 20493818
Notch pathway regulation (2) UbcD6 Upregulation of Notch pathway; wing disc NRE:EGFP: up; wing disc myrRFP: accumulation; lethal sp en-GAL4 20493818
Notch pathway regulation (2) UbcD6 Upregulation of Notch pathway; wing pouch: crumbled sp C96-GAL4 20493818
Notch pathway regulation (3) UbcD6 Upregulation of Notch pathway np   20493818
Adiposity regulation (1) UbcD6 none -0.24   20074523
Adiposity regulation (1) UbcD6 none -0.005   20074523
RTK-Ras-ERK pathway regulation (1) UbcD6 Decreased ERK phosphorylation after EGF stimulation -1.54 0 minutes EGF stimulation 22028469

0 Submissions