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Gene : Prp19 D. melanogaster

DB identifier  ? FBgn0261119 Secondary Identifier  ? CG5519
Name  ? Prp19 Source  FlyBase
  • synonyms:
  • GTP-binding regulatory protein beta chain,
  • FBgn0261119,
  • CG5519,
  • FBan0005519,
  • BcDNA:LD02793,
  • Gbp,
  • prp19,
  • l(2)07838,
  • FBgn0013969,
  • FBgn0010644,
  • GPB,
  • FBgn0027900

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Genomics

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5 Alleles

DB identifier Symbol Allele Class Organism
FBal0238913 Prp19[G3080]   Drosophila melanogaster
FBal0257336 Prp19[HMS00652]   Drosophila melanogaster
FBal0008134 Prp19[07838]   Drosophila melanogaster
FBal0207097 Prp19[GD11681]   Drosophila melanogaster
FBal0231206 Prp19[KK101335]   Drosophila melanogaster

51 Clones

Secondary Identifier DB identifier
AT01653 FBcl0037375
AT11427 FBcl0037377
AT31940 FBcl0037379
UUGC1070 FBcl0005719
EK101615 FBcl0032682
EK295711 FBcl0032710
EK178813 FBcl0032762
GM05881 FBcl0143074
HL01142 FBcl0149655
LD02793 FBcl0156802
LD14747 FBcl0156811
LD08810 FBcl0156813
LD15707 FBcl0156824
LD14214 FBcl0156827
LD39558 FBcl0170668
LD47390 FBcl0170674
LD36344 FBcl0170685
LD29139 FBcl0170689
LD22378 FBcl0170690
LD26529 FBcl0170694
LD27519 FBcl0170696
LD32933 FBcl0170698
LD47510 FBcl0170700
RE59354 FBcl0214643
RE69819 FBcl0214646
RE60535 FBcl0214650
RE37484 FBcl0214653
RE06121 FBcl0214657
RE69566 FBcl0214660
RE32108 FBcl0214662

3 Exons

DB identifier Symbol
FBgn0261119:3 Prp19:3
FBgn0261119:2 Prp19:2
FBgn0261119:1 Prp19:1

1 Transcripts

DB identifier Gene
FBtr0086723 Prp19

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0086723-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0086723-3-prime-utr Drosophila melanogaster

Interactions

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Other

0 Pathways

3 Cross References

Identifier
Source . Name

Subject . Primary Identifier
37123 NCBI Entrez Gene identifiers FBgn0261119
36936 NCBI Entrez Gene identifiers FBgn0261119
62799 BioGRID FBgn0261119

10 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  

0 Expression Scores

2 Introns

DB identifier
Organism . Name
intron_FBgn0261119:3_FBgn0261119:2 Drosophila melanogaster
intron_FBgn0261119:2_FBgn0261119:1 Drosophila melanogaster

31 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Prp19 none 0.278722275   19067489
Lipid storage Prp19 none -4,00E-06   19067489
Multipolar division Prp19 Centrosome clustering defects weak   18662975
Constitutive protein secretion and Golgi organization (1) Prp19 Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) Prp19 none sp   16496002
Microtubule assembly and organization Prp19 none np   18463163
Muscle morphogenesis and function (1) Prp19 Lethal np   20220848
Muscle morphogenesis and function (1) Prp19 Lethal np   20220848
Muscle morphogenesis and function (1) Prp19 none np   20220848
Muscle morphogenesis and function (3) Prp19 none np   20220848
Heat nociception (1) Prp19 Increased noxious heat avoidance 2.47   21074052
Heat nociception (1) Prp19 none -0.45   21074052
Heat nociception (1) Prp19 Developmentally lethal 1.45   21074052
Heart development and function (1) Prp19 none 1   20371351
Heart development and function (2) Prp19 none 2.74   20371351
Serratia marcescens infection (1) Prp19 none 0.422222222222222   19520911
Notch pathway regulation (4) Prp19 Completely lethal (pupal) sp   19363474
Notch pathway regulation (4) Prp19 Completely lethal (before pupal) sp   19363474
Notch pathway regulation (4) Prp19 none 0   19363474
Adiposity regulation (1) Prp19 none -0.131   20074523
Blood cell homeostasis regulation (1) Prp19 Increased melanotic mass formation np   20540764
Blood cell homeostasis regulation (2) Prp19 none np   20540764
Blood cell homeostasis regulation (3) Prp19 Increased melanotic mass formation 9.3   20540764
Blood cell homeostasis regulation (4) Prp19 none 0   20540764
Blood cell homeostasis regulation (5) Prp19 none 0   20540764
Blood cell homeostasis regulation (6) Prp19 Increased melanotic mass formation 35.3   20540764
Blood cell homeostasis regulation (7) Prp19 none 0   20540764
Blood cell homeostasis regulation (8) Prp19 Increased melanotic mass formation 22.7   20540764
Hippo pathway regulation Prp19 none -0.76   23263283
Glycosylation regulation (1) Prp19 none sp   21203496

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