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Gene : Fas2 D. melanogaster

DB identifier  ? FBgn0000635 Secondary Identifier  ? CG3665
Name  ? Fasciclin 2 Source  FlyBase
  • synonyms:
  • l(1)G0293,
  • anon-EST:Liang-1.60,
  • FAS2,
  • FASCICLIN II,
  • fasciclin 2,
  • clone 1.60,
  • FBgn0040202,
  • mAb 1D4,
  • fasciclin-II,
  • Fasciclin-2,
  • Fasiclin II,
  • FBgn0026682,
  • MAB1D4,
  • 1D4,
  • FASII,
  • FBgn0027230,
  • FasciclinII,
  • FASCICLIN,
  • CG3665,
  • Fascilin II,
  • l(1)G0336,
  • Fasciclin2,
  • Fascicilin II,
  • EG:EG0007.3,
  • Fasciculin II,
  • FBan0003665,
  • FAS II,
  • Ab 1D4,
  • l(1)G0081,
  • l(1)G0032,
  • FBgn0028323,
  • FascII,
  • FBgn0000635,
  • l(1)G0048,
  • Fas 2,
  • FAS 11,
  • Fas,
  • CT12301,
  • Fas-II,
  • FBgn0040201

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79 Alleles

DB identifier Symbol Allele Class Organism
FBal0211680 Fas2[CB03613]   Drosophila melanogaster
FBal0240330 Fas2[JF02918]   Drosophila melanogaster
FBal0198220 Fas2[MB04516]   Drosophila melanogaster
FBal0183593 Fas2[d09440]   Drosophila melanogaster
FBal0183595 Fas2[d04749]   Drosophila melanogaster
FBal0183594 Fas2[d07111]   Drosophila melanogaster
FBal0277899 Fas2[CPTI001335]   Drosophila melanogaster
FBal0152497 Fas2[G0485]   Drosophila melanogaster
FBal0152498 Fas2[G0480]   Drosophila melanogaster
FBal0152499 Fas2[G0457]   Drosophila melanogaster
FBal0152500 Fas2[G0454]   Drosophila melanogaster
FBal0152501 Fas2[G0439]   Drosophila melanogaster
FBal0152504 Fas2[G0101]   Drosophila melanogaster
FBal0150807 Fas2[spin]   Drosophila melanogaster
FBal0029777 Fas2[MB2225]   Drosophila melanogaster
FBal0257762 Fas2[HMS01098]   Drosophila melanogaster
FBal0123172 Fas2[EP1462]   Drosophila melanogaster
FBal0066095 Fas2[HSA.1]   Drosophila melanogaster
FBal0152505 Fas2[G0081]   Drosophila melanogaster
FBal0152503 Fas2[G0293]   Drosophila melanogaster
FBal0095724 Fas2[GS1069]   Drosophila melanogaster
FBal0152502 Fas2[G0336]   Drosophila melanogaster
FBal0152506 Fas2[G0048]   Drosophila melanogaster
FBal0152507 Fas2[G0032]   Drosophila melanogaster
FBal0131047 Fas2[BG00173]   Drosophila melanogaster
FBal0131044 Fas2[PL84]   Drosophila melanogaster
FBal0131045 Fas2[PL38]   Drosophila melanogaster
FBal0131046 Fas2[PL108]   Drosophila melanogaster
FBal0269890 Fas2[C.Scer\UAS]   Drosophila melanogaster
FBal0269891 Fas2[PEST+.AAE.Scer\UAS]   Drosophila melanogaster

167 Clones

Secondary Identifier DB identifier
DPiM_GH15080 FBcl0742057
RP003224118 FBcl0483297
RP004251097 FBcl0483700
RP004191024 FBcl0483702
RP004200776 FBcl0483701
RP004075368 FBcl0483703
RP004423851 FBcl0483713
RP004476896 FBcl0483705
RP004391297 FBcl0483704
RP004216884 FBcl0483706
RP004387545 FBcl0483707
RP004062097 FBcl0483709
RP004549302 FBcl0483708
RP004135950 FBcl0483710
RP004545768 FBcl0483712
RP004546469 FBcl0483711
RP004260501 FBcl0483715
RP004511051 FBcl0483714
RP004486913 FBcl0483716
AT03528 FBcl0030139
EK173730 FBcl0053752
CK00447 FBcl0060063
EK092458 FBcl0062244
EK180810 FBcl0062890
EK207414 FBcl0064066
EK066401 FBcl0065688
EK235143 FBcl0066174
EK263751 FBcl0066250
EK211326 FBcl0066356
EK135550 FBcl0066366

17 Exons

DB identifier Symbol
FBgn0000635:12 Fas2:12
FBgn0000635:16 Fas2:16
FBgn0000635:15 Fas2:15
FBgn0000635:14 Fas2:14
FBgn0000635:13 Fas2:13
FBgn0000635:11 Fas2:11
FBgn0000635:10 Fas2:10
FBgn0000635:9 Fas2:9
FBgn0000635:6 Fas2:6
FBgn0000635:1 Fas2:1
FBgn0000635:3 Fas2:3
FBgn0000635:2 Fas2:2
FBgn0000635:7 Fas2:7
FBgn0000635:8 Fas2:8
FBgn0000635:17 Fas2:17
FBgn0000635:4 Fas2:4
FBgn0000635:5 Fas2:5

8 Transcripts

DB identifier Gene
FBtr0343524 Fas2
FBtr0336884 Fas2
FBtr0336883 Fas2
FBtr0070666 Fas2
FBtr0070667 Fas2
FBtr0343523 Fas2
FBtr0070665 Fas2
FBtr0336882 Fas2

16 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0070665-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0070666-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0070667-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0336882-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0336883-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0336884-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0343523-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0343524-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0070665-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0070666-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0070667-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0336882-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0336883-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0336884-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0343523-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0343524-3-prime-utr Drosophila melanogaster

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0 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
31364 NCBI Entrez Gene identifiers FBgn0000635
57881 BioGRID FBgn0000635

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0000635 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 643.0
FBgn0000635 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 860.0
FBgn0000635 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 252.0
FBgn0000635 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 329.0
FBgn0000635 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 2291.0
FBgn0000635 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 269.0
FBgn0000635 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 343.0
FBgn0000635 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 218.0
FBgn0000635 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 171.0
FBgn0000635 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 120.0
FBgn0000635 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 667.0
FBgn0000635 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 180.0
FBgn0000635 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 577.0
FBgn0000635 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 316.0
FBgn0000635 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 1892.0
FBgn0000635 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 398.0
FBgn0000635 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1062.0
FBgn0000635 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 662.0
FBgn0000635 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 489.0
FBgn0000635 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 807.0
FBgn0000635 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 1630.0
FBgn0000635 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 713.0
FBgn0000635 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 733.0
FBgn0000635 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 414.0
FBgn0000635 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 252.0
FBgn0000635 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 302.0
FBgn0000635 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 358.0
FBgn0000635 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 1060.0
FBgn0000635 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1646.0
FBgn0000635 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 2731.0

19 Introns

DB identifier
Organism . Name
intron_FBgn0000635:16_FBgn0000635:15 Drosophila melanogaster
intron_FBgn0000635:15_FBgn0000635:14 Drosophila melanogaster
intron_FBgn0000635:14_FBgn0000635:13 Drosophila melanogaster
intron_FBgn0000635:13_FBgn0000635:12 Drosophila melanogaster
intron_FBgn0000635:12_FBgn0000635:11 Drosophila melanogaster
intron_FBgn0000635:11_FBgn0000635:10 Drosophila melanogaster
intron_FBgn0000635:10_FBgn0000635:9 Drosophila melanogaster
intron_FBgn0000635:9_FBgn0000635:6 Drosophila melanogaster
intron_FBgn0000635:6_FBgn0000635:1 Drosophila melanogaster
intron_FBgn0000635:17_FBgn0000635:15 Drosophila melanogaster
intron_FBgn0000635:14_FBgn0000635:12 Drosophila melanogaster
intron_FBgn0000635:6_FBgn0000635:4 Drosophila melanogaster
intron_FBgn0000635:4_FBgn0000635:2 Drosophila melanogaster
intron_FBgn0000635:6_FBgn0000635:5 Drosophila melanogaster
intron_FBgn0000635:6_FBgn0000635:3 Drosophila melanogaster
intron_FBgn0000635:3_FBgn0000635:2 Drosophila melanogaster
intron_FBgn0000635:9_FBgn0000635:7 Drosophila melanogaster
intron_FBgn0000635:10_FBgn0000635:8 Drosophila melanogaster
intron_FBgn0000635:6_FBgn0000635:2 Drosophila melanogaster

35 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Fas2 none 0.460528625   19067489
Lipid storage Fas2 none -1.240548076   19067489
Lipid storage Fas2 none -0.571901336   19067489
Lipid storage Fas2 none 1.234017494   19067489
Lipid storage Fas2 none -0.796333417   19067489
Constitutive protein secretion and Golgi organization (1) Fas2 Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) Fas2 none sp   16496002
Cell size and cell-cycle regulation (1) Fas2 none sp   16496002
Muscle morphogenesis and function (1) Fas2 none np   20220848
Muscle morphogenesis and function (1) Fas2 none np   20220848
Muscle morphogenesis and function (1) Fas2 none np   20220848
Muscle morphogenesis and function (1) Fas2 none np   20220848
Heat nociception (1) Fas2 none -0.6   21074052
Heat nociception (1) Fas2 none -0.19   21074052
Heat nociception (1) Fas2 Developmentally lethal 0   21074052
Heart development and function (1) Fas2 none 1   20371351
Heart development and function (1) Fas2 none 1   20371351
Serratia marcescens infection (1) Fas2 none 0.134615384615384   19520911
Notch pathway regulation (4) Fas2 Loss of bristles 4   19363474
Notch pathway regulation (4) Fas2 Loss of bristles, bristle morphology defects sp   19363474
Notch pathway regulation (4) Fas2 Loss of bristles, bristle morphology defects, planar polarity defects, notum malformation death sp   19363474
Notch pathway regulation (4) Fas2 Loss of bristles, bristle morphology defects, notum malformation death sp   19363474
Notch induced transcription Fas2 none 0.095983 without Notch stimulation 20959007
Notch induced transcription Fas2 Upregulation of Notch pathway after Notch stimulation 2.2388 N(delta)ecn Notch stimulation 20959007
Notch induced transcription Fas2 none 1.018 N(delta)ecn Notch stimulation 20959007
Adiposity regulation (1) Fas2 none 0.125   20074523
Secretory pathway regulation Fas2 Decreased BiP signal peptide and firefly luciferase fusion protein expression (-2) - (-1.5)   19942856
RTK-Ras-ERK pathway regulation (1) Fas2 none -1.01 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) Fas2 Increased ERK phosphorylation after EGF stimulation 1.81 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Fas2 none -0.4 10 minutes sSpitz stimulation 22028469

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