Genomics
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56 Alleles
65 Clones
8 Exons
| DB identifier | Symbol |
|---|---|
| FBgn0086358:1 | Tab2:1 |
| FBgn0086358:3 | Tab2:3 |
| FBgn0086358:4 | Tab2:4 |
| FBgn0086358:6 | Tab2:6 |
| FBgn0086358:2 | Tab2:2 |
| FBgn0086358:5 | Tab2:5 |
| FBgn0086358:7 | Tab2:7 |
| FBgn0086358:8 | Tab2:8 |
6 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0086516-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0331925-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0305333-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0086516-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0331925-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0305333-3-prime-utr | Drosophila melanogaster |
Other
34 Pathways
- MyD88-independent cascade,
- JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1,
- Signaling by ERBB4,
- Signaling Pathways,
- Immune System,
- TAK1 activates NFkB by phosphorylation and activation of IKKs complex,
- MyD88:Mal cascade initiated on plasma membrane,
- MAP kinase activation in TLR cascade,
- Toll Like Receptor 3 (TLR3) Cascade,
- Innate Immune System,
- Signaling by Interleukins,
- Toll Like Receptor 2 (TLR2) Cascade,
- IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation,
- Nuclear signaling by ERBB4,
- Toll Like Receptor 4 (TLR4) Cascade,
- IRAK2 mediated activation of TAK1 complex,
- Activated TLR4 signalling,
- MyD88 cascade initiated on plasma membrane,
- Toll Like Receptor 7/8 (TLR7/8) Cascade,
- TRIF-mediated TLR3/TLR4 signaling,
- Toll Like Receptor 10 (TLR10) Cascade,
- Toll Like Receptor TLR1:TLR2 Cascade,
- NOD1/2 Signaling Pathway,
- Interleukin-1 signaling,
- Toll-Like Receptors Cascades,
- Toll Like Receptor 5 (TLR5) Cascade,
- Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways,
- Cytokine Signaling in Immune system,
- activated TAK1 mediates p38 MAPK activation,
- Toll Like Receptor TLR6:TLR2 Cascade,
- TRAF6 Mediated Induction of proinflammatory cytokines,
- Toll Like Receptor 9 (TLR9) Cascade,
- MyD88 dependent cascade initiated on endosome,
- TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
2 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 37216 | NCBI Entrez Gene identifiers | FBgn0086358 |
| 62880 | BioGRID | FBgn0086358 |
10 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| TrEMBL data set | http://www.ebi.ac.uk/trembl/ |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| Panther data set | |
| IntAct interactions data set | |
| BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster | |
| Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
7 Introns
19 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Lipid storage | Tab2 | none | -1.125366234 | 19067489 | |
| Lipid storage | Tab2 | none | -0.088991981 | 19067489 | |
| Innate immunity | Tab2 | Decreased IMD reporter activity | np | 16163390 | |
| Cell size and cell-cycle regulation (1) | Tab2 | none | sp | 16496002 | |
| Dendrite pattern formation | Tab2 | Misrouting | np | 16547170 | |
| Muscle morphogenesis and function (1) | Tab2 | none | np | 20220848 | |
| Muscle morphogenesis and function (1) | Tab2 | none | np | 20220848 | |
| Heat nociception (1) | Tab2 | none | -0.48 | 21074052 | |
| Heat nociception (1) | Tab2 | none | -0.17 | 21074052 | |
| Heart development and function (1) | Tab2 | none | 1 | 20371351 | |
| Heart development and function (1) | Tab2 | none | 1 | 20371351 | |
| Serratia marcescens infection (1) | Tab2 | none | 0.898734177215189 | 19520911 | |
| Notch pathway regulation (4) | Tab2 | Gain of bristles, colour defects, lateral inhibition | sp | 19363474 | |
| Notch pathway regulation (4) | Tab2 | Gain of bristles, hair cell duplication, lateral inhibition | sp | 19363474 | |
| Notch pathway regulation (5) | Tab2 | none | np | 19363474 | |
| Notch pathway regulation (5) | Tab2 | none | np | 19363474 | |
| PGN-induced dJNK phosphorylation | Tab2 | Decreased P-JNK protein expression with PGN | -4.28 | 15 min PGN induction | 19893628 |
| Adiposity regulation (1) | Tab2 | none | -0.289 | 20074523 | |
| Hippo pathway regulation | Tab2 | none | -0.43 | 23263283 |
