Genomics
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8 Alleles
DB identifier | Symbol | Allele Class | Organism |
---|---|---|---|
FBal0220512 | Bub3[1] | Drosophila melanogaster | |
FBal0257470 | Bub3[HMS00789] | Drosophila melanogaster | |
FBal0198512 | Bub3[T:Avic\GFP-EGFP] | Drosophila melanogaster | |
FBal0148370 | Bub3[233] | Drosophila melanogaster | |
FBal0287502 | Bub3[Scer\UAS.ORF.T:Ivir\HA1] | Drosophila melanogaster | |
FBal0198851 | Bub3[GD9924] | Drosophila melanogaster | |
FBal0279190 | Bub3[HMS02158] | Drosophila melanogaster | |
FBal0275631 | Bub3[NIG.7581R] | Drosophila melanogaster |
104 Clones
4 UTRs
Class | DB identifier |
Organism . Name |
---|---|---|
FivePrimeUTR | FBtr0085465-5-prime-utr | Drosophila melanogaster |
FivePrimeUTR | FBtr0339148-5-prime-utr | Drosophila melanogaster |
ThreePrimeUTR | FBtr0085465-3-prime-utr | Drosophila melanogaster |
ThreePrimeUTR | FBtr0339148-3-prime-utr | Drosophila melanogaster |
Other
13 Pathways
- APC/C-mediated degradation of cell cycle proteins,
- Inactivation of APC/C via direct inhibition of the APC/C complex,
- Cell Cycle, Mitotic,
- Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components,
- Regulation of APC/C activators between G1/S and early anaphase,
- Regulation of mitotic cell cycle,
- Amplification of signal from the kinetochores,
- Cell Cycle,
- Cdc20:Phospho-APC/C mediated degradation of Cyclin A,
- Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal,
- Mitotic Spindle Checkpoint,
- APC-Cdc20 mediated degradation of Nek2A,
- Cell Cycle Checkpoints
2 Cross References
Identifier |
Source . Name |
Subject . Primary Identifier |
---|---|---|
43490 | NCBI Entrez Gene identifiers | FBgn0025457 |
68354 | BioGRID | FBgn0025457 |
11 Data Sets
Name | URL |
---|---|
FlyBase data set for Drosophila melanogaster | |
TrEMBL data set | http://www.ebi.ac.uk/trembl/ |
Drosophila 12 Genomes Consortium homology | |
GenomeRNAi data set | |
TreeFam data set | |
Panther data set | |
IntAct interactions data set | |
BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
GO Annotation from FlyBase | |
FlyBase fasta data set for Drosophila melanogaster | |
Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
2 Introns
DB identifier |
Organism . Name |
---|---|
intron_FBgn0025457:3_FBgn0025457:2 | Drosophila melanogaster |
intron_FBgn0025457:3_FBgn0025457:1 | Drosophila melanogaster |
15 RNAi Results
Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
---|---|---|---|---|---|
Lipid storage | Bub3 | none | 0.254773427 | 19067489 | |
L. monocytogenes infection | Bub3 | Fewer infected cells, fewer bacteria per cell | ** | 16157870 | |
Cell size and cell-cycle regulation (1) | Bub3 | none | sp | 16496002 | |
Mitosis | Bub3 | Chromosome misalignment | np | 17412918 | |
Mitochondrial biogenesis and function | Bub3 | Decreased mitochondrial citrate synthase activity | 0.67 | 18042644 | |
Microtubule assembly and organization | Bub3 | none | np | 18463163 | |
Muscle morphogenesis and function (1) | Bub3 | none | np | 20220848 | |
Heat nociception (1) | Bub3 | none | -1.17 | 21074052 | |
Heart development and function (1) | Bub3 | none | 1 | 20371351 | |
Serratia marcescens infection (1) | Bub3 | none | 0.403225806451612 | 19520911 | |
Notch pathway regulation (4) | Bub3 | Loss of bristles, bristle morphology defects | sp | 19363474 | |
Adiposity regulation (1) | Bub3 | none | -0.102 | 20074523 | |
Hippo pathway regulation | Bub3 | none | -1.03 | 23263283 | |
Glycosylation regulation (1) | Bub3 | none | sp | 21203496 | |
Huntingtin (Htt) aggregates formation | Bub3 | Decreased formation of mutant Huntingtin (Httex1-Qn) protein aggregates | np | 20100940 |