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Gene : aPKC D. melanogaster

DB identifier  ? FBgn0261854 Secondary Identifier  ? CG42783
Name  ? atypical protein kinase C Source  FlyBase
  • synonyms:
  • atypical protein kinase,
  • FBan0030475,
  • Atypical Protein Kinase C,
  • alphaPKCzeta,
  • CG30475,
  • FBgn0050475,
  • l(2)k06403,
  • CG10261,
  • PKCzeta,
  • FBgn0261854,
  • atypical-Protein Kinase C,
  • Atypical PKC,
  • aPKCzeta,
  • DaPKC,
  • a-PKC,
  • aPKC-zeta,
  • PKCl,i,
  • FBgn0022131,
  • FBgn0033986,
  • psu,
  • pschur,
  • FBgn0260478,
  • apkc,
  • CG42783,
  • pkc-3,
  • FBan0010261

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47 Alleles

DB identifier Symbol Allele Class Organism
FBal0277054 aPKC[ts] temperature conditional hypomorphic allele Drosophila melanogaster
FBal0277055 aPKC[Scer\UAS.P\T.T:Hsap\MYC]   Drosophila melanogaster
FBal0277056 aPKC[ts.Scer\UAS.P\T.T:Hsap\MYC]   Drosophila melanogaster
FBal0283061 aPKC[Scer\UAS.P\T.T:Uuuu\CAAX]   Drosophila melanogaster
FBal0155670 aPKC[psu69] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0155673 aPKC[psu141] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0155672 aPKC[psu265] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0155671 aPKC[psu417]   Drosophila melanogaster
FBal0192232 aPKC[EY22946]   Drosophila melanogaster
FBal0181026 aPKC[e02056]   Drosophila melanogaster
FBal0258618 aPKC[S330A.T422A.Scer\UAS]   Drosophila melanogaster
FBal0181025 aPKC[e04135]   Drosophila melanogaster
FBal0064438 aPKC[k06403] loss of function allele, amorphic allele - genetic evidence Drosophila melanogaster
FBal0257913 aPKC[HMS01320]   Drosophila melanogaster
FBal0137333 aPKC[KG06602]   Drosophila melanogaster
FBal0287764 aPKC[MI09330]   Drosophila melanogaster
FBal0197866 aPKC[unspecified]   Drosophila melanogaster
FBal0213848 aPKC[GD14814]   Drosophila melanogaster
FBal0286131 aPKC[PKM.hs]   Drosophila melanogaster
FBal0147313 aPKC[dsRNA.cCa]   Drosophila melanogaster
FBal0144479 aPKC[dsRNA.cBa]   Drosophila melanogaster
FBal0159526 aPKC[Exc55]   Drosophila melanogaster
FBal0159527 aPKC[EX48]   Drosophila melanogaster
FBal0134129 aPKC[p622]   Drosophila melanogaster
FBal0191358 aPKC[dsRNA.301-900]   Drosophila melanogaster
FBal0262499 aPKC[GL00007]   Drosophila melanogaster
FBal0278807 aPKC[HMS01689]   Drosophila melanogaster
FBal0144482 aPKC[DeltaN.Scer\UAS]   Drosophila melanogaster
FBal0189627 aPKC[CAAXDN.Scer\UAS]   Drosophila melanogaster
FBal0192028 aPKC[CAAXWT.Scer\UAS]   Drosophila melanogaster

71 Clones

Secondary Identifier DB identifier
EK227936 FBcl0019160
EK188541 FBcl0019336
EK190363 FBcl0019420
EK170943 FBcl0019460
EK191432 FBcl0016886
EK123164 FBcl0017570
EK100404 FBcl0018110
EK069707 FBcl0018150
EK125608 FBcl0018170
EK131715 FBcl0018188
EK103441 FBcl0018198
EK304751 FBcl0018236
EK038340 FBcl0018244
EK066418 FBcl0018256
EK136723 FBcl0018266
EK106033 FBcl0018276
EK139354 FBcl0018286
EK066426 FBcl0018296
EK180605 FBcl0018306
EK151849 FBcl0018316
EK262404 FBcl0018326
EK181121 FBcl0018332
EK129818 FBcl0018344
EK256828 FBcl0018350
EK250419 FBcl0018358
EK293320 FBcl0018368
EK101102 FBcl0018406
EK065433 FBcl0019012
EC35787 FBcl0069481
EC36987 FBcl0069483

24 Exons

DB identifier Symbol
FBgn0261854:19 aPKC:19
FBgn0261854:18 aPKC:18
FBgn0261854:17 aPKC:17
FBgn0261854:12 aPKC:12
FBgn0261854:11 aPKC:11
FBgn0261854:10 aPKC:10
FBgn0261854:9 aPKC:9
FBgn0261854:7 aPKC:7
FBgn0261854:6 aPKC:6
FBgn0261854:3 aPKC:3
FBgn0261854:14 aPKC:14
FBgn0261854:5 aPKC:5
FBgn0261854:2 aPKC:2
FBgn0261854:13 aPKC:13
FBgn0261854:15 aPKC:15
FBgn0261854:23 aPKC:23
FBgn0261854:21 aPKC:21
FBgn0261854:20 aPKC:20
FBgn0261854:8 aPKC:8
FBgn0261854:4 aPKC:4
FBgn0261854:24 aPKC:24
FBgn0261854:22 aPKC:22
FBgn0261854:1 aPKC:1
FBgn0261854:16 aPKC:16

12 Transcripts

DB identifier Gene
FBtr0303435 aPKC
FBtr0329887 aPKC
FBtr0303432 aPKC
FBtr0303431 aPKC
FBtr0303430 aPKC
FBtr0303437 aPKC
FBtr0329890 aPKC
FBtr0303433 aPKC
FBtr0329889 aPKC
FBtr0303429 aPKC
FBtr0303434 aPKC
FBtr0329888 aPKC

24 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0329887-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0329888-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0329889-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0329890-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0303429-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0303430-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0303431-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0303432-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0303433-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0303434-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0303435-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0303437-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0329887-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0329888-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0329889-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0329890-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0303429-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0303430-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0303431-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0303432-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0303433-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0303434-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0303435-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0303437-3-prime-utr Drosophila melanogaster

Interactions

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
47594 NCBI Entrez Gene identifiers FBgn0261854
70851 BioGRID FBgn0261854

10 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  

0 Expression Scores

26 Introns

DB identifier
Organism . Name
intron_FBgn0261854:14_FBgn0261854:12 Drosophila melanogaster
intron_FBgn0261854:12_FBgn0261854:11 Drosophila melanogaster
intron_FBgn0261854:11_FBgn0261854:10 Drosophila melanogaster
intron_FBgn0261854:10_FBgn0261854:9 Drosophila melanogaster
intron_FBgn0261854:9_FBgn0261854:7 Drosophila melanogaster
intron_FBgn0261854:7_FBgn0261854:6 Drosophila melanogaster
intron_FBgn0261854:6_FBgn0261854:5 Drosophila melanogaster
intron_FBgn0261854:5_FBgn0261854:2 Drosophila melanogaster
intron_FBgn0261854:13_FBgn0261854:12 Drosophila melanogaster
intron_FBgn0261854:6_FBgn0261854:3 Drosophila melanogaster
intron_FBgn0261854:15_FBgn0261854:12 Drosophila melanogaster
intron_FBgn0261854:9_FBgn0261854:8 Drosophila melanogaster
intron_FBgn0261854:8_FBgn0261854:6 Drosophila melanogaster
intron_FBgn0261854:6_FBgn0261854:4 Drosophila melanogaster
intron_FBgn0261854:23_FBgn0261854:21 Drosophila melanogaster
intron_FBgn0261854:21_FBgn0261854:20 Drosophila melanogaster
intron_FBgn0261854:20_FBgn0261854:12 Drosophila melanogaster
intron_FBgn0261854:24_FBgn0261854:21 Drosophila melanogaster
intron_FBgn0261854:22_FBgn0261854:21 Drosophila melanogaster
intron_FBgn0261854:5_FBgn0261854:1 Drosophila melanogaster
intron_FBgn0261854:8_FBgn0261854:7 Drosophila melanogaster
intron_FBgn0261854:19_FBgn0261854:18 Drosophila melanogaster
intron_FBgn0261854:18_FBgn0261854:16 Drosophila melanogaster
intron_FBgn0261854:16_FBgn0261854:12 Drosophila melanogaster
intron_FBgn0261854:18_FBgn0261854:17 Drosophila melanogaster
intron_FBgn0261854:17_FBgn0261854:12 Drosophila melanogaster

36 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage aPKC none 0.845673361   19067489
Lipid storage aPKC none 0.242934176   19067489
Cell cycle regulation (1) aPKC none np   15616552
Cell cycle regulation (2) aPKC none np   15616552
Cell size and cell-cycle regulation (1) aPKC none sp   16496002
Cell size and cell-cycle regulation (1) aPKC none sp   16496002
Muscle morphogenesis and function (1) aPKC none np   20220848
Heart development and function (1) aPKC none 1   20371351
Serratia marcescens infection (1) aPKC none -0.028169014084507   19520911
Notch pathway regulation (1) aPKC none no phenotype temperature: 18 19363474
Notch pathway regulation (1) aPKC none no phenotype temperature: 25 19363474
Notch pathway regulation (1) aPKC none no phenotype temperature: 29 19363474
Notch pathway regulation (2) aPKC Lethal lethal temperature: 29 19363474
Notch pathway regulation (2) aPKC Loss of bristles and gain of bristles on same fly medium to strong temperature: 25 19363474
Notch pathway regulation (2) aPKC none no phenotype temperature: 18 19363474
Notch pathway regulation (3) aPKC Rare empty or multiple sockets, loss of bristles rare, weak temperature: 18 19363474
Notch pathway regulation (3) aPKC Notum death malformation rare, weak temperature: 25 19363474
Notch pathway regulation (3) aPKC Lethal lethal temperature: 29 19363474
Notch pathway regulation (4) aPKC Completely lethal (pupal) sp   19363474
Notch pathway regulation (1) aPKC Upregulation of Notch pathway np   20493818
Notch pathway regulation (2) aPKC Downregulation of Notch pathway; adult wing margin: notches sp C96-GAL4 20493818
Notch pathway regulation (2) aPKC Up- and downregulation of Notch pathway; adult wing veins: disrupted, broader; adult wing margin: notches; wing disc NRE:EGFP: up, broader, gap sp en-GAL4 20493818
Notch pathway regulation (3) aPKC none np   20493818
Adiposity regulation (1) aPKC none 0.386   20074523
Blood cell homeostasis regulation (1) aPKC none np   20540764
Blood cell homeostasis regulation (2) aPKC none np   20540764
Actin organization and cell morphology (1) aPKC none np   19265526
Actin organization and cell morphology (2) aPKC none np   19265526
Actin organization and cell morphology (3) aPKC none np   19265526
Actin organization and cell morphology (4) aPKC none np   19265526

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