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Gene : rok D. melanogaster

DB identifier  ? FBgn0026181 Secondary Identifier  ? CG9774
Name  ? Rho-kinase Source  FlyBase
  • synonyms:
  • FBgn0026181,
  • Rho-associated kinase,
  • DRho-kinase,
  • unnamed,
  • FBan0009774,
  • FBgn0028698,
  • ROCK2,
  • ROK,
  • ROCK1,
  • Drosophila rho-associated kinase,
  • DRhk,
  • RhoK,
  • RhoA kinase,
  • Rhk,
  • ROKalpha/beta,
  • Rok/ROCK,
  • CG9774,
  • ROCK,
  • RHO kinase,
  • DROK,
  • ROCK-1

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29 Alleles

DB identifier Symbol Allele Class Organism
FBal0241064 rok[f04065]   Drosophila melanogaster
FBal0257904 rok[HMS01311]   Drosophila melanogaster
FBal0260724 rok[Scer\UAS.P\T.T:Ivir\HA1]   Drosophila melanogaster
FBal0260792 rok[K116A.Scer\UAS.P\T.T:Avic\GFP-YFP.Venus]   Drosophila melanogaster
FBal0260793 rok[CA.Scer\UAS.P\T.T:Ivir\HA1]   Drosophila melanogaster
FBal0266158 rok[K116A.Scer\UAS]   Drosophila melanogaster
FBal0288676 rok[RBD.Scer\UAS.P\T.T:Avic\GFP]   Drosophila melanogaster
FBal0288677 rok[sqh.T:Avic\GFP]   Drosophila melanogaster
FBal0248404 rok[SBD.Scer\UAS.T:Hsap\MYC]   Drosophila melanogaster
FBal0286662 rok[Scer\UAS.ORF]   Drosophila melanogaster
FBal0286663 rok[Scer\UAS.ORF.T:Ivir\HA1]   Drosophila melanogaster
FBal0122920 rok[alphaTub84B.PW]   Drosophila melanogaster
FBal0158717 rok[dsRNA.cHa]   Drosophila melanogaster
FBal0122918 rok[2]   Drosophila melanogaster
FBal0122919 rok[1]   Drosophila melanogaster
FBal0178173 rok[dsRNA.cRa]   Drosophila melanogaster
FBal0122915 rok[unspecified]   Drosophila melanogaster
FBal0262682 rok[GL00209]   Drosophila melanogaster
FBal0122917 rok[CAT-KG.Scer\UAS]   Drosophila melanogaster
FBal0122916 rok[CAT.Scer\UAS]   Drosophila melanogaster
FBal0137096 rok[Scer\UAS.cMa]   Drosophila melanogaster
FBal0244145 rok[VDRC.cUa]   Drosophila melanogaster
FBal0246223 rok[cat.GMR]   Drosophila melanogaster
FBal0239723 rok[JF03225]   Drosophila melanogaster
FBal0246224 rok[cat.Scer\UAS]   Drosophila melanogaster
FBal0194567 rok[dsRNA.cHb]   Drosophila melanogaster
FBal0210486 rok[GD1522]   Drosophila melanogaster
FBal0235174 rok[KK107802]   Drosophila melanogaster
FBal0276556 rok[NIG.9774R]   Drosophila melanogaster

36 Clones

Secondary Identifier DB identifier
EP11712 FBcl0075691
EK061546 FBcl0116468
EK200619 FBcl0116472
EK185213 FBcl0116520
EK249653 FBcl0116594
EK173328 FBcl0117150
EK209415 FBcl0117154
EK130059 FBcl0117338
GM08108 FBcl0138405
GM09611 FBcl0138411
LD15203 FBcl0153071
LD11891 FBcl0153354
LD35732 FBcl0163623
LD40656 FBcl0166218
LD31445 FBcl0166219
LD40268 FBcl0166237
LD36258 FBcl0166242
EC052017 FBcl0298995
EC052014 FBcl0298996
EC051781 FBcl0298997
EC055185 FBcl0298998
EC051513 FBcl0298999
EC052514 FBcl0299000
EC055975 FBcl0299001
CK01.79A.D12 FBcl0433835
FGC004A01 FBcl0384831
FGC023G03 FBcl0385869
146808 FBcl0433767
FI04037 FBcl0474602
11017 FBcl0433762

15 Exons

DB identifier Symbol
FBgn0026181:15 rok:15
FBgn0026181:14 rok:14
FBgn0026181:12 rok:12
FBgn0026181:11 rok:11
FBgn0026181:10 rok:10
FBgn0026181:9 rok:9
FBgn0026181:8 rok:8
FBgn0026181:6 rok:6
FBgn0026181:5 rok:5
FBgn0026181:4 rok:4
FBgn0026181:2 rok:2
FBgn0026181:7 rok:7
FBgn0026181:1 rok:1
FBgn0026181:13 rok:13
FBgn0026181:3 rok:3

4 Transcripts

DB identifier Gene
FBtr0340152 rok
FBtr0340151 rok
FBtr0074286 rok
FBtr0340153 rok

8 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0074286-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0340151-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0340152-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0340153-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0074286-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0340151-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0340152-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0340153-3-prime-utr Drosophila melanogaster

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3 Cross References

Identifier
Source . Name

Subject . Primary Identifier
43916 NCBI Entrez Gene identifiers FBgn0026181
40904 NCBI Entrez Gene identifiers FBgn0026181
68714 BioGRID FBgn0026181

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0026181 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 733.0
FBgn0026181 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 824.0
FBgn0026181 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1041.0
FBgn0026181 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 894.0
FBgn0026181 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1076.0
FBgn0026181 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 464.0
FBgn0026181 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 2471.0
FBgn0026181 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 1217.0
FBgn0026181 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 482.0
FBgn0026181 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1407.0
FBgn0026181 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1025.0
FBgn0026181 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 853.0
FBgn0026181 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1167.0
FBgn0026181 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 1190.0
FBgn0026181 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 3374.0
FBgn0026181 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 1166.0
FBgn0026181 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1198.0
FBgn0026181 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1388.0
FBgn0026181 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1954.0
FBgn0026181 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1376.0
FBgn0026181 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 2194.0
FBgn0026181 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 1498.0
FBgn0026181 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 1033.0
FBgn0026181 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 963.0
FBgn0026181 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 938.0
FBgn0026181 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 3766.0
FBgn0026181 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 2583.0
FBgn0026181 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 2213.0
FBgn0026181 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1887.0
FBgn0026181 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1815.0

15 Introns

DB identifier
Organism . Name
intron_FBgn0026181:15_FBgn0026181:14 Drosophila melanogaster
intron_FBgn0026181:14_FBgn0026181:12 Drosophila melanogaster
intron_FBgn0026181:12_FBgn0026181:11 Drosophila melanogaster
intron_FBgn0026181:11_FBgn0026181:10 Drosophila melanogaster
intron_FBgn0026181:10_FBgn0026181:9 Drosophila melanogaster
intron_FBgn0026181:9_FBgn0026181:8 Drosophila melanogaster
intron_FBgn0026181:8_FBgn0026181:6 Drosophila melanogaster
intron_FBgn0026181:6_FBgn0026181:5 Drosophila melanogaster
intron_FBgn0026181:5_FBgn0026181:4 Drosophila melanogaster
intron_FBgn0026181:4_FBgn0026181:2 Drosophila melanogaster
intron_FBgn0026181:13_FBgn0026181:12 Drosophila melanogaster
intron_FBgn0026181:4_FBgn0026181:3 Drosophila melanogaster
intron_FBgn0026181:9_FBgn0026181:7 Drosophila melanogaster
intron_FBgn0026181:7_FBgn0026181:6 Drosophila melanogaster
intron_FBgn0026181:4_FBgn0026181:1 Drosophila melanogaster

43 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage rok none -1.820162033   19067489
Lipid storage rok none -0.712501984   19067489
Lipid storage rok none 0.025573497   19067489
Lipid storage rok none -0.262043598   19067489
Neural outgrowth rok Excess branching np   18604272
Cell morphology rok Morphology np   14527345
Cell cycle regulation (1) rok All mitotic defects, central spindle defects sp   15616552
Cell cycle regulation (2) rok none np   15616552
Cytokinesis rok Multi-nucleate cells np   15380073
Cytokinesis regulation rok Binucleate cells weak   15547975
Cell size and cell-cycle regulation (1) rok Decreased G2 DNA content sp   16496002
Cell size and cell-cycle regulation (1) rok none sp   16496002
Cell size and cell-cycle regulation (1) rok none sp   16496002
Cell size and cell-cycle regulation (2) rok none 1.314   16496002
Cell size and cell-cycle regulation (3) rok none 470   16496002
C. trachomatis infection rok C. trachomatis infection down np   18369471
Muscle morphogenesis and function (1) rok none np   20220848
Heat nociception (1) rok none -1.17   21074052
Heart development and function (1) rok none 1   20371351
Serratia marcescens infection (1) rok none -1.26760563380281   19520911
Notch pathway regulation (4) rok Planar polarity defects, overproliferation sp   19363474
Notch induced transcription rok none 0.86739 N(delta)ecn Notch stimulation 20959007
Notch induced transcription rok none -2.1565 without Notch stimulation 20959007
Notch induced transcription rok Downregulation of Notch pathway after Notch stimulation -2.1834 N(delta)ecn Notch stimulation 20959007
Adiposity regulation (1) rok none -0.618   20074523
Blood cell homeostasis regulation (1) rok none np   20540764
Blood cell homeostasis regulation (1) rok none np   20540764
Blood cell homeostasis regulation (2) rok none np   20540764
Blood cell homeostasis regulation (2) rok none np   20540764
Actin organization and cell morphology (1) rok none np   19265526

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