Genomics
Gene Ontology Displayer
Homologue Displayer
Mod Mine G Browse Displayer
Overlapping Features Displayer
Regulatory Regions Displayer
16 Alleles
| DB identifier | Symbol | Allele Class | Organism |
|---|---|---|---|
| FBal0283860 | lack[MI07104] | Drosophila melanogaster | |
| FBal0147051 | lack[15C] | Drosophila melanogaster | |
| FBal0147052 | lack[11R] | Drosophila melanogaster | |
| FBal0147050 | lack[KG07014] | Drosophila melanogaster | |
| FBal0151754 | lack[dsRNA.si.cLa] | Drosophila melanogaster | |
| FBal0197536 | lack[unspecified] | Drosophila melanogaster | |
| FBal0151757 | lack[C1029A.Scer\UAS.T:Zzzz\FLAG] | Drosophila melanogaster | |
| FBal0151756 | lack[MtnA.T:Hsap\MYC] | Drosophila melanogaster | |
| FBal0151755 | lack[Scer\UAS.T:Zzzz\FLAG] | Drosophila melanogaster | |
| FBal0232222 | lack[KK103197] | Drosophila melanogaster | |
| FBal0247824 | lack[MI02327] | Drosophila melanogaster | |
| FBal0209896 | lack[GD11480] | Drosophila melanogaster | |
| FBal0279185 | lack[HMS02153] | Drosophila melanogaster | |
| FBal0279572 | lack[Scer\UAS.P\T.cXa] | Drosophila melanogaster | |
| FBal0288091 | lack[s-160] | Drosophila melanogaster | |
| FBal0274449 | lack[NIG.4943R] | Drosophila melanogaster |
123 Clones
9 Exons
| DB identifier | Symbol |
|---|---|
| FBgn0029006:1 | lack:1 |
| FBgn0029006:2 | lack:2 |
| FBgn0029006:3 | lack:3 |
| FBgn0029006:4 | lack:4 |
| FBgn0029006:5 | lack:5 |
| FBgn0029006:6 | lack:6 |
| FBgn0029006:7 | lack:7 |
| FBgn0029006:8 | lack:8 |
| FBgn0029006:9 | lack:9 |
4 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0086833-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0333168-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0086833-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0333168-3-prime-utr | Drosophila melanogaster |
Other
26 Pathways
- Downregulation of SMAD2/3:SMAD4 transcriptional activity,
- Signaling by NODAL,
- Loss of Function of TGFBR2 in Cancer,
- Loss of Function of SMAD2/3 in Cancer,
- TGFBR2 MSI Frameshift Mutants in Cancer,
- SMAD2/3 Phosphorylation Motif Mutants in Cancer,
- TGFBR1 LBD Mutants in Cancer,
- Loss of Function of TGFBR1 in Cancer,
- Gene Expression,
- TGFBR2 Kinase Domain Mutants in Cancer,
- Disease,
- Loss of Function of SMAD4 in Cancer,
- Developmental Biology,
- TGF-beta receptor signaling activates SMADs,
- TGFBR1 KD Mutants in Cancer,
- Signaling Pathways,
- Signaling by TGF-beta Receptor Complex in Cancer,
- Signaling by TGF-beta Receptor Complex,
- Signaling by BMP,
- Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer,
- SMAD2/3 MH2 Domain Mutants in Cancer,
- Downregulation of TGF-beta receptor signaling,
- SMAD4 MH2 Domain Mutants in Cancer,
- Signaling by Activin,
- Generic Transcription Pathway,
- SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
2 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 36999 | NCBI Entrez Gene identifiers | FBgn0029006 |
| 62687 | BioGRID | FBgn0029006 |
11 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| Swiss-Prot data set | http://ca.expasy.org/sprot |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| IntAct interactions data set | |
| BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster | |
| Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
8 Introns
19 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Lipid storage | lack | none | -0.983428779 | 19067489 | |
| Lipid storage | lack | none | 0.33953235 | 19067489 | |
| L. monocytogenes infection | lack | Escape pff LLO- strain | ** | 16157870 | |
| L. monocytogenes infection | lack | Fewer infected cells | ** | 16157870 | |
| Cell size and cell-cycle regulation (1) | lack | none | sp | 16496002 | |
| Muscle morphogenesis and function (1) | lack | none | np | 20220848 | |
| Muscle morphogenesis and function (1) | lack | none | np | 20220848 | |
| Heat nociception (1) | lack | none | -1.17 | 21074052 | |
| Heat nociception (1) | lack | none | -0.72 | 21074052 | |
| Heart development and function (1) | lack | none | 1 | 20371351 | |
| Serratia marcescens infection (1) | lack | none | 0.247191011235955 | 19520911 | |
| Notch pathway regulation (4) | lack | none | 0 | 19363474 | |
| Notch pathway regulation (4) | lack | Colour defects, notum malformation migration | sp | 19363474 | |
| RTK-Ras-ERK pathway regulation (1) | lack | Increased ERK phosphorylation after EGF stimulation | 1.68 | 0 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (1) | lack | none | -1.16 | 10 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | lack | none | 0.01 | 30 minutes sSpitz stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | lack | none | 0.18 | 10 minutes sSpitz stimulation | 22028469 |
| Hippo pathway regulation | lack | none | 2.07 | 23263283 | |
| Glycosylation regulation (1) | lack | none | sp | 21203496 |
