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Gene : Iap2 D. melanogaster

DB identifier  ? FBgn0015247 Secondary Identifier  ? CG8293
Name  ? Inhibitor of apoptosis 2 Source  FlyBase
  • synonyms:
  • DIAP2,
  • IAP-like protein,
  • IAP2,
  • Ilp,
  • Drosophila inhibitor of apoptosis 2,
  • FBgn0015247,
  • DIAP-2,
  • CG8293,
  • DIAPII,
  • inhibitor of apoptosis 2,
  • IAP,
  • DIAP,
  • D-IAP2,
  • FBan0008293,
  • DIHA,
  • Inhibitor of Apoptosis Protein 2,
  • dILP,
  • Drosophila melanogaster inhibitor of apoptosis 2

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37 Alleles

DB identifier Symbol Allele Class Organism
FBal0270255 Iap2[RINGmut.Scer\UAS]   Drosophila melanogaster
FBal0270256 Iap2[Scer\UAS.attB]   Drosophila melanogaster
FBal0270257 Iap2[BIR2mut.Scer\UAS]   Drosophila melanogaster
FBal0270258 Iap2[BIR3mut.Scer\UAS]   Drosophila melanogaster
FBal0270259 Iap2[BIR23mut.Scer\UAS]   Drosophila melanogaster
FBal0246795 Iap2[Scer\UAS.cLa]   Drosophila melanogaster
FBal0212206 Iap2[G2534]   Drosophila melanogaster
FBal0212207 Iap2[E151]   Drosophila melanogaster
FBal0212208 Iap2[E119]   Drosophila melanogaster
FBal0212209 Iap2[+t7.4Wt]   Drosophila melanogaster
FBal0212210 Iap2[7.4C472Y]   Drosophila melanogaster
FBal0212211 Iap2[miRNA.Scer\UAS]   Drosophila melanogaster
FBal0243966 Iap2[7c] amorphic allele - genetic evidence Drosophila melanogaster
FBal0243967 Iap2[7a] amorphic allele - genetic evidence Drosophila melanogaster
FBal0048824 Iap2[GMR.PH]   Drosophila melanogaster
FBal0183148 Iap2[dsRNA.hs]   Drosophila melanogaster
FBal0095672 Iap2[Tahbilk-CA7]   Drosophila melanogaster
FBal0122090 Iap2[MtnA.PQ]   Drosophila melanogaster
FBal0150770 Iap2[dsRNA.cZa]   Drosophila melanogaster
FBal0104109 Iap2[cKa]   Drosophila melanogaster
FBal0263090 Iap2[HMS00085]   Drosophila melanogaster
FBal0191697 Iap2[dsRNA.Scer\UAS]   Drosophila melanogaster
FBal0125396 Iap2[MtnA.T:Ivir\HA1]   Drosophila melanogaster
FBal0144790 Iap2[MtnA.T:Zzzz\TAP]   Drosophila melanogaster
FBal0104760 Iap2[Scer\UAS.cIa]   Drosophila melanogaster
FBal0124167 Iap2[Scer\UAS.cWa]   Drosophila melanogaster
FBal0218262 Iap2[Scer\UAS.cMa]   Drosophila melanogaster
FBal0207359 Iap2[GD1466]   Drosophila melanogaster
FBal0244198 Iap2[C46G.Scer\UAS]   Drosophila melanogaster
FBal0244199 Iap2[C149G.Scer\UAS]   Drosophila melanogaster

61 Clones

Secondary Identifier DB identifier
DPiM_LD34777 FBcl0741327
AT07235 FBcl0011699
AT27633 FBcl0011739
AT08930 FBcl0011759
AT29023 FBcl0011779
AT16591 FBcl0011807
AT13761 FBcl0011823
AT06227 FBcl0011839
AT12539 FBcl0011867
EK191237 FBcl0014726
EK258938 FBcl0014770
EK182826 FBcl0014812
EK121948 FBcl0014868
EK112725 FBcl0014876
EK010202 FBcl0015002
EP04536 FBcl0076745
GH16694 FBcl0115037
GH06609 FBcl0115043
GH02994 FBcl0115045
GH25140 FBcl0115049
GM02492 FBcl0138923
HL02681 FBcl0149394
LD14926 FBcl0155394
LD04614 FBcl0155396
LD08372 FBcl0155398
LD17728 FBcl0155404
LD34777 FBcl0168881
LD36539 FBcl0168892
LD34310 FBcl0168893
LP12287 FBcl0183852

5 Exons

DB identifier Symbol
FBgn0015247:4 Iap2:4
FBgn0015247:2 Iap2:2
FBgn0015247:1 Iap2:1
FBgn0015247:5 Iap2:5
FBgn0015247:3 Iap2:3

2 Transcripts

DB identifier Gene
FBtr0087296 Iap2
FBtr0087297 Iap2

4 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0087296-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0087297-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0087296-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0087297-3-prime-utr Drosophila melanogaster

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0 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
36748 NCBI Entrez Gene identifiers FBgn0015247
62475 BioGRID FBgn0015247

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0015247 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 833.0
FBgn0015247 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 755.0
FBgn0015247 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 747.0
FBgn0015247 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 734.0
FBgn0015247 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1165.0
FBgn0015247 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 418.0
FBgn0015247 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 767.0
FBgn0015247 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 2343.0
FBgn0015247 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 1090.0
FBgn0015247 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1119.0
FBgn0015247 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1032.0
FBgn0015247 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 981.0
FBgn0015247 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 562.0
FBgn0015247 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 664.0
FBgn0015247 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 634.0
FBgn0015247 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 888.0
FBgn0015247 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 823.0
FBgn0015247 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 634.0
FBgn0015247 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 847.0
FBgn0015247 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 573.0
FBgn0015247 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 951.0
FBgn0015247 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 789.0
FBgn0015247 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 698.0
FBgn0015247 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1616.0
FBgn0015247 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 577.0
FBgn0015247 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 1456.0
FBgn0015247 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 842.0
FBgn0015247 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 693.0
FBgn0015247 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 721.0
FBgn0015247 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 809.0

4 Introns

DB identifier
Organism . Name
intron_FBgn0015247:4_FBgn0015247:2 Drosophila melanogaster
intron_FBgn0015247:2_FBgn0015247:1 Drosophila melanogaster
intron_FBgn0015247:5_FBgn0015247:3 Drosophila melanogaster
intron_FBgn0015247:3_FBgn0015247:2 Drosophila melanogaster

16 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Iap2 none -0.886415917   19067489
Lipid storage Iap2 none 1.199197303   19067489
Innate immunity Iap2 Decreased IMD/Rel reporter activity -2.5   16170305
Innate immunity Iap2 Decreased IMD reporter activity np   16163390
Cell size and cell-cycle regulation (1) Iap2 none sp   16496002
Muscle morphogenesis and function (1) Iap2 none np   20220848
Muscle morphogenesis and function (1) Iap2 none np   20220848
Heat nociception (1) Iap2 none -0.62   21074052
Heart development and function (1) Iap2 none 1   20371351
Serratia marcescens infection (1) Iap2 none 0   19520911
Notch pathway regulation (4) Iap2 Notum malformation death 3   19363474
Notch pathway regulation (4) Iap2 Colour defects, bristle morphology defects sp   19363474
PGN-induced dJNK phosphorylation Iap2 Decreased P-JNK protein expression with PGN -2.76 15 min PGN induction 19893628
Adiposity regulation (1) Iap2 none -0.107   20074523
Hippo pathway regulation Iap2 none 0.5   23263283
Glycosylation regulation (1) Iap2 Lethal np   21203496

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