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Gene : Mdh1 D. melanogaster

DB identifier  ? FBgn0262782 Secondary Identifier  ? CG5362
Name  ? Malate dehydrogenase 1 Source  FlyBase
  • synonyms:
  • CT17038,
  • Malate dehydrogenase,
  • FBgn0262782,
  • FBgn0032237,
  • FBgn0002699,
  • cytosolic malate dehydrogenase,
  • Mdh2,
  • MDH-1,
  • sMdh,
  • Malic DH,
  • MDH,
  • FBan0005362,
  • MdhD,
  • cMdh,
  • cytoplasmic Mdh,
  • CG5362

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18 Alleles

DB identifier Symbol Allele Class Organism
FBal0248486 Mdh1[Delta18.1] loss of function allele Drosophila melanogaster
FBal0248487 Mdh1[Delta10.5]   Drosophila melanogaster
FBal0259736 Mdh1[KK108844]   Drosophila melanogaster
FBal0012125 Mdh1[nNC2] loss of function allele Drosophila melanogaster
FBal0012124 Mdh1[nNC1] loss of function allele Drosophila melanogaster
FBal0176086 Mdh1[633T]   Drosophila melanogaster
FBal0012119 Mdh1[2a]   Drosophila melanogaster
FBal0029927 Mdh1[S]   Drosophila melanogaster
FBal0012123 Mdh1[n2] loss of function allele Drosophila melanogaster
FBal0012120 Mdh1[4]   Drosophila melanogaster
FBal0012118 Mdh1[2]   Drosophila melanogaster
FBal0029926 Mdh1[F]   Drosophila melanogaster
FBal0176087 Mdh1[552T]   Drosophila melanogaster
FBal0012122 Mdh1[n1] loss of function allele Drosophila melanogaster
FBal0012121 Mdh1[6]   Drosophila melanogaster
FBal0204655 Mdh1[GD11625]   Drosophila melanogaster
FBal0161287 Mdh1[EY08761]   Drosophila melanogaster
FBal0274641 Mdh1[NIG.5362R]   Drosophila melanogaster

324 Clones

Secondary Identifier DB identifier
UUGC0319 FBcl0000095
ESG0116b.B21_C04 FBcl0001983
UUGC0739 FBcl0004111
UUGC0778 FBcl0004407
EC35525 FBcl0070255
EC23768 FBcl0070263
EC36741 FBcl0070265
EC28547 FBcl0070267
EC22593 FBcl0070269
EC25895 FBcl0070271
EK068338 FBcl0098736
EK133513 FBcl0098816
EN02355 FBcl0099539
GH01866 FBcl0136239
GH02429 FBcl0136247
GH03701 FBcl0136251
GH06581 FBcl0136257
GH15418 FBcl0136259
GH15791 FBcl0136263
GH14652 FBcl0136265
GH07288 FBcl0136267
GH11026 FBcl0136269
GH22580 FBcl0136271
GH11216 FBcl0136273
GH01110 FBcl0136275
GH04879 FBcl0136277
GH01065 FBcl0136279
GH24135 FBcl0136281
GH13167 FBcl0136283
GH25557 FBcl0136285

2 Exons

DB identifier Symbol
FBgn0262782:2 Mdh1:2
FBgn0262782:1 Mdh1:1

1 Transcripts

DB identifier Gene
FBtr0080050 Mdh1

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0080050-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0080050-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
34414 NCBI Entrez Gene identifiers FBgn0262782
60498 BioGRID FBgn0262782

10 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  

0 Expression Scores

1 Introns

DB identifier
Organism . Name
intron_FBgn0262782:2_FBgn0262782:1 Drosophila melanogaster

21 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Mdh1 none -0.736386493   19067489
Lipid storage Mdh1 none 0.032561544   19067489
Cell size and cell-cycle regulation (1) Mdh1 none sp   16496002
Muscle morphogenesis and function (1) Mdh1 none np   20220848
Muscle morphogenesis and function (1) Mdh1 none np   20220848
Muscle morphogenesis and function (1) Mdh1 none np   20220848
Heat nociception (1) Mdh1 none -1.17   21074052
Heat nociception (1) Mdh1 none -1.17   21074052
Heat nociception (1) Mdh1 none -1.17   21074052
Heart development and function (1) Mdh1 none 1   20371351
Serratia marcescens infection (1) Mdh1 none 0.261904761904761   19520911
Notch pathway regulation (4) Mdh1 Gain of bristles, bristle morphology defects, notum malformation death, lateral inhibition sp   19363474
Notch pathway regulation (4) Mdh1 Notum malformation death 4   19363474
Notch pathway regulation (4) Mdh1 Bristle morphology defects, notum malformation death sp   19363474
Notch pathway regulation (5) Mdh1 Bent up (spoon-shaped) wing, wrinkled wings np   19363474
Notch pathway regulation (3) Mdh1 none np   20493818
Notch pathway regulation (4) Mdh1 Upregulation of Notch pathway; wing disc NRE:EGFP: up; wing disc myrRFP: accumulation, reduced sp en-GAL4 20493818
Adiposity regulation (1) Mdh1 none 0.026   20074523
Hippo pathway regulation Mdh1 none -1.58   23263283
Glycosylation regulation (1) Mdh1 Decreased (GlcNAc)n Chp glycosylation, decreased GlcNAcb1-4GlcNAc Chp glycosylation sp   21203496
Glycosylation regulation (2) Mdh1 none np   21203496

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