Genomics
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18 Alleles
103 Clones
5 Exons
| DB identifier | Symbol |
|---|---|
| FBgn0024222:5 | ird5:5 |
| FBgn0024222:4 | ird5:4 |
| FBgn0024222:3 | ird5:3 |
| FBgn0024222:2 | ird5:2 |
| FBgn0024222:1 | ird5:1 |
2 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0304804-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0304804-3-prime-utr | Drosophila melanogaster |
Other
74 Pathways
- DAP12 signaling,
- MyD88:Mal cascade initiated on plasma membrane,
- Adaptive Immune System,
- Fc epsilon receptor (FCERI) signaling,
- Signaling by NGF,
- Cytokine Signaling in Immune system,
- PI3K/AKT Signaling in Cancer,
- PI3K/AKT activation,
- Toll Like Receptor 7/8 (TLR7/8) Cascade,
- TRAF6 Mediated Induction of proinflammatory cytokines,
- PIP3 activates AKT signaling,
- RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways,
- Signaling by FGFR in disease,
- Activated TLR4 signalling,
- Signaling by EGFR in Cancer,
- CD28 co-stimulation,
- TCR signaling,
- TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation,
- Downstream signaling of activated FGFR,
- Toll Like Receptor 5 (TLR5) Cascade,
- Downstream signal transduction,
- Downstream TCR signaling,
- Toll Like Receptor 4 (TLR4) Cascade,
- Signaling by ERBB4,
- Activation of NF-kappaB in B Cells,
- PI-3K cascade,
- DAP12 interactions,
- Toll-Like Receptors Cascades,
- Downstream Signaling Events Of B Cell Receptor (BCR),
- GAB1 signalosome,
- FCERI mediated NF-kB activation,
- Constitutive PI3K/AKT Signaling in Cancer,
- AKT phosphorylates targets in the cytosol,
- JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1,
- Cytosolic sensors of pathogen-associated DNA,
- Signaling by Interleukins,
- Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways,
- RIP-mediated NFkB activation via ZBP1,
- Role of LAT2/NTAL/LAB on calcium mobilization,
- Toll Like Receptor 3 (TLR3) Cascade,
- activated TAK1 mediates p38 MAPK activation,
- MyD88 cascade initiated on plasma membrane,
- B Cell Activation,
- Signaling Pathways,
- Toll Like Receptor 10 (TLR10) Cascade,
- Signaling by FGFR,
- Disease,
- Signaling by PDGF,
- Signaling by EGFR,
- Signaling by SCF-KIT,
- TRAF6 mediated NF-kB activation,
- NGF signalling via TRKA from the plasma membrane,
- Costimulation by the CD28 family,
- Signaling by ERBB2,
- PI3K events in ERBB2 signaling,
- IRAK1 recruits IKK complex,
- Toll Like Receptor 2 (TLR2) Cascade,
- IRAK2 mediated activation of TAK1 complex,
- TAK1 activates NFkB by phosphorylation and activation of IKKs complex,
- CD28 dependent PI3K/Akt signaling,
- TRIF-mediated TLR3/TLR4 signaling,
- NOD1/2 Signaling Pathway,
- ZBP1(DAI) mediated induction of type I IFNs,
- Toll Like Receptor 9 (TLR9) Cascade,
- Immune System,
- Toll Like Receptor TLR1:TLR2 Cascade,
- PI3K events in ERBB4 signaling,
- Interleukin-1 signaling,
- MyD88 dependent cascade initiated on endosome,
- IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation,
- MyD88-independent cascade,
- MAP kinase activation in TLR cascade,
- Toll Like Receptor TLR6:TLR2 Cascade,
- Innate Immune System
2 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 44432 | NCBI Entrez Gene identifiers | FBgn0024222 |
| 69058 | BioGRID | FBgn0024222 |
11 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| Swiss-Prot data set | http://ca.expasy.org/sprot |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| IntAct interactions data set | |
| BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster | |
| Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
23 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Lipid storage | ird5 | none | -0.07505239 | 19067489 | |
| Lipid storage | ird5 | none | 3.760418376 | 19067489 | |
| Cell cycle regulation (1) | ird5 | none | np | 15616552 | |
| Cell cycle regulation (2) | ird5 | none | np | 15616552 | |
| Innate immunity | ird5 | Decreased IMD/Rel reporter activity | -6.5 | 16170305 | |
| Cell size and cell-cycle regulation (1) | ird5 | none | sp | 16496002 | |
| Cell size and cell-cycle regulation (1) | ird5 | none | sp | 16496002 | |
| Muscle morphogenesis and function (1) | ird5 | none | np | 20220848 | |
| Heat nociception (1) | ird5 | none | 0.12 | 21074052 | |
| Heart development and function (1) | ird5 | none | 1 | 20371351 | |
| Serratia marcescens infection (1) | ird5 | none | -0.683333333333333 | 19520911 | |
| Notch pathway regulation (4) | ird5 | none | 0 | 19363474 | |
| PGN-induced dJNK phosphorylation | ird5 | Increased P-JNK protein expression with PGN | 6.23 | 15 min PGN induction | 19893628 |
| PGN-induced dJNK phosphorylation | ird5 | Increased P-JNK protein expression with PGN | 7.74 | 60 min PGN induction | 19893628 |
| Adiposity regulation (1) | ird5 | none | 0.08 | 20074523 | |
| Actin organization and cell morphology (1) | ird5 | none | np | 19265526 | |
| Actin organization and cell morphology (2) | ird5 | none | np | 19265526 | |
| Actin organization and cell morphology (3) | ird5 | none | np | 19265526 | |
| Actin organization and cell morphology (4) | ird5 | Altered cell morphology | np | 19265526 | |
| Actin organization and cell morphology (5) | ird5 | none | np | 19265526 | |
| Actin organization and cell morphology (6) | ird5 | Altered cell morphology | np | 19265526 | |
| Vaccinia virus infection | ird5 | none | sp | 20585561 | |
| Hippo pathway regulation | ird5 | none | 1.5 | 23263283 |
