Genomics
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15 Alleles
| DB identifier | Symbol | Allele Class | Organism |
|---|---|---|---|
| FBal0281205 | RpS5a[GL01502] | Drosophila melanogaster | |
| FBal0284507 | RpS5a[Scer\UAS.T:Avic\GFP] | Drosophila melanogaster | |
| FBal0152244 | RpS5a[BG02071] | Drosophila melanogaster | |
| FBal0011878 | RpS5a[1] | Drosophila melanogaster | |
| FBal0147535 | RpS5a[dsRNA.cLa] | Drosophila melanogaster | |
| FBal0052190 | RpS5a[R28ts] | Drosophila melanogaster | |
| FBal0048855 | RpS5a[unspecified] | Drosophila melanogaster | |
| FBal0011879 | RpS5a[2] | Drosophila melanogaster | |
| FBal0220075 | RpS5a[G11272] | Drosophila melanogaster | |
| FBal0287419 | RpS5a[Scer\UAS.ORF] | Drosophila melanogaster | |
| FBal0287420 | RpS5a[Scer\UAS.ORF.T:Ivir\HA1] | Drosophila melanogaster | |
| FBal0208392 | RpS5a[GD14071] | Drosophila melanogaster | |
| FBal0214760 | RpS5a[GD17542] | Drosophila melanogaster | |
| FBal0236187 | RpS5a[KK109271] | Drosophila melanogaster | |
| FBal0276210 | RpS5a[NIG.8922R] | Drosophila melanogaster |
366 Clones
7 Exons
| DB identifier | Symbol |
|---|---|
| FBgn0002590:7 | RpS5a:7 |
| FBgn0002590:4 | RpS5a:4 |
| FBgn0002590:3 | RpS5a:3 |
| FBgn0002590:2 | RpS5a:2 |
| FBgn0002590:1 | RpS5a:1 |
| FBgn0002590:6 | RpS5a:6 |
| FBgn0002590:5 | RpS5a:5 |
6 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0074406-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0343292-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0343293-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0074406-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0343292-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0343293-3-prime-utr | Drosophila melanogaster |
Other
52 Pathways
- Eukaryotic Translation Initiation,
- Gene Expression,
- RNA Polymerase II Promoter Escape,
- RNA Polymerase II Transcription Initiation And Promoter Clearance,
- RNA Polymerase II Pre-transcription Events,
- 3' -UTR-mediated translational regulation,
- Translation,
- Processing of Capped Intronless Pre-mRNA,
- L13a-mediated translational silencing of Ceruloplasmin expression,
- Formation of RNA Pol II elongation complex,
- Nonsense-Mediated Decay,
- Transport of the SLBP Dependant Mature mRNA,
- Transport of Mature mRNAs Derived from Intronless Transcripts,
- RNA Pol II CTD phosphorylation and interaction with CE,
- Processing of Capped Intron-Containing Pre-mRNA,
- mRNA Processing,
- mRNA Capping,
- Transport of the SLBP independent Mature mRNA,
- Transport of Mature mRNA derived from an Intron-Containing Transcript,
- Processing of Intronless Pre-mRNAs,
- Recycling of eIF2:GDP,
- RNA Polymerase II Transcription Pre-Initiation And Promoter Opening,
- Metabolism of mRNA,
- Post-Elongation Processing of the Transcript,
- RNA Polymerase II Transcription,
- Cleavage of Growing Transcript in the Termination Region,
- Eukaryotic Translation Elongation,
- Transport of Mature Transcript to Cytoplasm,
- RNA Polymerase II Transcription Elongation,
- Transcription,
- Transport of Mature mRNA Derived from an Intronless Transcript,
- Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S,
- SRP-dependent cotranslational protein targeting to membrane,
- Post-Elongation Processing of Intronless pre-mRNA,
- Metabolism of RNA,
- Eukaryotic Translation Termination,
- SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs,
- Peptide chain elongation,
- GTP hydrolysis and joining of the 60S ribosomal subunit,
- Formation of the Early Elongation Complex,
- Translation initiation complex formation,
- Formation of the ternary complex, and subsequently, the 43S complex,
- Metabolism of proteins,
- Formation of a pool of free 40S subunits,
- Nonsense Mediated Decay Independent of the Exon Junction Complex,
- SLBP independent Processing of Histone Pre-mRNAs,
- RNA Polymerase II Transcription Termination,
- Cap-dependent Translation Initiation,
- Nonsense Mediated Decay Enhanced by the Exon Junction Complex,
- RNA Polymerase II Transcription Initiation,
- Ribosomal scanning and start codon recognition,
- Elongation arrest and recovery
2 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 32700 | NCBI Entrez Gene identifiers | FBgn0002590 |
| 59029 | BioGRID | FBgn0002590 |
11 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| Swiss-Prot data set | http://ca.expasy.org/sprot |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| IntAct interactions data set | |
| BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster | |
| Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
6 Introns
30 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Lipid storage | RpS5a | Increased lipid droplet area | 2.420013115 | 19067489 | |
| Lipid storage | RpS5a | Increased lipid droplet area | 2.714912317 | 19067489 | |
| Hedgehog signaling | RpS5a | Decreased Hedgehog reporter activity | np | 12663920 | |
| Intracellular Listeria monocytogenes infection | RpS5a | Increased GFP protein expression | moderate | 16020693 | |
| Hedgehog signaling | RpS5a | Decreased Hedgehog reporter activity | -4.49 | 16311596 | |
| Constitutive protein secretion and Golgi organization (1) | RpS5a | Decreased horseradish peroxidase protein expression | sp | 16452979 | |
| Cell size and cell-cycle regulation (1) | RpS5a | none | sp | 16496002 | |
| Influenza replication | RpS5a | Decreased Influenza replication | -2.06/-3.53 | 18615016 | |
| Lipid storage | RpS5a | More dispersed droplets | strong (but ribosomal) | 18408709 | |
| Muscle morphogenesis and function (1) | RpS5a | Lethal | np | 20220848 | |
| Muscle morphogenesis and function (1) | RpS5a | Lethal | np | 20220848 | |
| Muscle morphogenesis and function (2) | RpS5a | Wing posture / locomotion / ability to fly defect or lethal / semi-lethal | np | 20220848 | |
| Muscle morphogenesis and function (3) | RpS5a | Fading Z-line | np | 20220848 | |
| Heat nociception (1) | RpS5a | none | -1.17 | 21074052 | |
| Regulated secretory pathway biogenesis (1) | RpS5a | none | 0.2 | 21149569 | |
| Heart development and function (1) | RpS5a | Larval lethal | 0 | 20371351 | |
| Serratia marcescens infection (1) | RpS5a | Decreased viability after Serratia marcescens infection | -4.0327868852459 | 19520911 | |
| Serratia marcescens infection (2) | RpS5a | none | sp | 19520911 | |
| Serratia marcescens infection (6) | RpS5a | Larval lethality or failure to eclose | np | 19520911 | |
| Notch pathway regulation (4) | RpS5a | Completely lethal (before pupal) | sp | 19363474 | |
| Notch pathway regulation (4) | RpS5a | Completely lethal (before pupal) | sp | 19363474 | |
| PGN-induced dJNK phosphorylation | RpS5a | Increased P-JNK protein expression with PGN | 2.23 | 60 min PGN induction | 19893628 |
| Hh pathway regulation | RpS5a | none | -0.171057901357231 | 17903264 | |
| Adiposity regulation (1) | RpS5a | none | -0.306 | 20074523 | |
| RTK-Ras-ERK pathway regulation (1) | RpS5a | none | 0.18 | 0 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (1) | RpS5a | Decreased ERK phosphorylation after EGF stimulation | -2.18 | 10 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | RpS5a | Increased ERK phosphorylation after sSpitz and EGF stimulation | 1.64 | 10 minutes sSpitz stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | RpS5a | Increased ERK phosphorylation after sSpitz and EGF stimulation | 3.41 | 30 minutes sSpitz stimulation | 22028469 |
| Hippo pathway regulation | RpS5a | none | -2.67 | 23263283 | |
| Glycosylation regulation (1) | RpS5a | Decreased Chp protein expression | np | 21203496 |
