Genomics
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58 Alleles
35 Clones
6 Exons
| DB identifier | Symbol |
|---|---|
| FBgn0033402:6 | Myd88:6 |
| FBgn0033402:5 | Myd88:5 |
| FBgn0033402:4 | Myd88:4 |
| FBgn0033402:3 | Myd88:3 |
| FBgn0033402:2 | Myd88:2 |
| FBgn0033402:1 | Myd88:1 |
4 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0088598-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0333000-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0088598-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0333000-3-prime-utr | Drosophila melanogaster |
Other
34 Pathways
- Toll Like Receptor 7/8 (TLR7/8) Cascade,
- Toll Like Receptor 10 (TLR10) Cascade,
- MyD88-independent cascade,
- TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation,
- Trafficking and processing of endosomal TLR,
- Interleukin-1 signaling,
- MyD88 cascade initiated on plasma membrane,
- Signaling by Interleukins,
- Toll Like Receptor 9 (TLR9) Cascade,
- Activated TLR4 signalling,
- Toll Like Receptor 4 (TLR4) Cascade,
- TRAF6 Mediated Induction of proinflammatory cytokines,
- RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways,
- Cytokine Signaling in Immune system,
- NOD1/2 Signaling Pathway,
- Toll-Like Receptors Cascades,
- TRAF6 mediated NF-kB activation,
- Toll Like Receptor 3 (TLR3) Cascade,
- Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways,
- Innate Immune System,
- Immune System,
- DEx/H-box helicases activate type I IFN and inflammatory cytokines production,
- Cytosolic sensors of pathogen-associated DNA,
- Toll Like Receptor TLR6:TLR2 Cascade,
- ZBP1(DAI) mediated induction of type I IFNs,
- Toll Like Receptor TLR1:TLR2 Cascade,
- MyD88 dependent cascade initiated on endosome,
- IRAK2 mediated activation of TAK1 complex,
- MyD88:Mal cascade initiated on plasma membrane,
- Toll Like Receptor 2 (TLR2) Cascade,
- TRIF-mediated TLR3/TLR4 signaling,
- Toll Like Receptor 5 (TLR5) Cascade,
- RIP-mediated NFkB activation via ZBP1,
- TAK1 activates NFkB by phosphorylation and activation of IKKs complex
2 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 35956 | NCBI Entrez Gene identifiers | FBgn0033402 |
| 61792 | BioGRID | FBgn0033402 |
11 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| TrEMBL data set | http://www.ebi.ac.uk/trembl/ |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| IntAct interactions data set | |
| BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster | |
| Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
5 Introns
15 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Lipid storage | Myd88 | none | 0.030305328 | 19067489 | |
| Lipid storage | Myd88 | none | 0.055685606 | 19067489 | |
| Cell size and cell-cycle regulation (1) | Myd88 | none | sp | 16496002 | |
| C. trachomatis infection | Myd88 | C. trachomatis infection down | np | 18369471 | |
| Muscle morphogenesis and function (1) | Myd88 | none | np | 20220848 | |
| Muscle morphogenesis and function (1) | Myd88 | none | np | 20220848 | |
| Heat nociception (1) | Myd88 | none | -1.17 | 21074052 | |
| Heat nociception (1) | Myd88 | none | 0.16 | 21074052 | |
| Heart development and function (1) | Myd88 | none | 1 | 20371351 | |
| Serratia marcescens infection (1) | Myd88 | none | 0.466666666666666 | 19520911 | |
| Notch pathway regulation (4) | Myd88 | none | 0 | 19363474 | |
| Notch pathway regulation (4) | Myd88 | none | 0 | 19363474 | |
| Toll-dependent innate immune pathway regulation | Myd88 | Downregulation of Toll pathway after hEGF stimulation | -10.15 | 20375635 | |
| Adiposity regulation (1) | Myd88 | none | 0.272 | 20074523 | |
| Hippo pathway regulation | Myd88 | none | -1.36 | 23263283 |
