Genomics
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7 Alleles
| DB identifier | Symbol | Allele Class | Organism |
|---|---|---|---|
| FBal0286433 | RpL6[Scer\UAS.ORF] | Drosophila melanogaster | |
| FBal0286434 | RpL6[Scer\UAS.ORF.T:Ivir\HA1] | Drosophila melanogaster | |
| FBal0257637 | RpL6[HMS00967] | Drosophila melanogaster | |
| FBal0155943 | RpL6[EY02193] | Drosophila melanogaster | |
| FBal0208359 | RpL6[GD7320] | Drosophila melanogaster | |
| FBal0270895 | RpL6[NIG.11522R] | Drosophila melanogaster | |
| FBal0235381 | RpL6[KK108144] | Drosophila melanogaster |
576 Clones
4 Exons
| DB identifier | Symbol |
|---|---|
| FBgn0039857:4 | RpL6:4 |
| FBgn0039857:3 | RpL6:3 |
| FBgn0039857:1 | RpL6:1 |
| FBgn0039857:2 | RpL6:2 |
4 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0085804-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0085805-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0085804-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0085805-3-prime-utr | Drosophila melanogaster |
Other
49 Pathways
- RNA Polymerase II Transcription Elongation,
- SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs,
- Eukaryotic Translation Elongation,
- Processing of Intronless Pre-mRNAs,
- L13a-mediated translational silencing of Ceruloplasmin expression,
- RNA Polymerase II Pre-transcription Events,
- Cap-dependent Translation Initiation,
- 3' -UTR-mediated translational regulation,
- mRNA Capping,
- RNA Pol II CTD phosphorylation and interaction with CE,
- Metabolism of mRNA,
- Metabolism of proteins,
- Gene Expression,
- Processing of Capped Intronless Pre-mRNA,
- GTP hydrolysis and joining of the 60S ribosomal subunit,
- Cleavage of Growing Transcript in the Termination Region,
- mRNA Processing,
- Transport of Mature mRNA derived from an Intron-Containing Transcript,
- RNA Polymerase II Promoter Escape,
- Transport of the SLBP Dependant Mature mRNA,
- RNA Polymerase II Transcription Initiation And Promoter Clearance,
- Post-Elongation Processing of Intronless pre-mRNA,
- Post-Elongation Processing of the Transcript,
- Processing of Capped Intron-Containing Pre-mRNA,
- Ribosomal scanning and start codon recognition,
- RNA Polymerase II Transcription Termination,
- Eukaryotic Translation Initiation,
- Metabolism of RNA,
- Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S,
- Formation of RNA Pol II elongation complex,
- Nonsense-Mediated Decay,
- Nonsense Mediated Decay Independent of the Exon Junction Complex,
- RNA Polymerase II Transcription Pre-Initiation And Promoter Opening,
- RNA Polymerase II Transcription Initiation,
- Transport of the SLBP independent Mature mRNA,
- Translation,
- Formation of the Early Elongation Complex,
- Nonsense Mediated Decay Enhanced by the Exon Junction Complex,
- Transport of Mature mRNAs Derived from Intronless Transcripts,
- SLBP independent Processing of Histone Pre-mRNAs,
- Transport of Mature Transcript to Cytoplasm,
- RNA Polymerase II Transcription,
- SRP-dependent cotranslational protein targeting to membrane,
- Transcription,
- Eukaryotic Translation Termination,
- Formation of a pool of free 40S subunits,
- Elongation arrest and recovery,
- Peptide chain elongation,
- Transport of Mature mRNA Derived from an Intronless Transcript
2 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 43723 | NCBI Entrez Gene identifiers | FBgn0039857 |
| 68566 | BioGRID | FBgn0039857 |
11 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| TrEMBL data set | http://www.ebi.ac.uk/trembl/ |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| IntAct interactions data set | |
| BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster | |
| Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
39 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Lipid storage | RpL6 | Increased lipid droplet area | 2.441083367 | 19067489 | |
| Lipid storage | RpL6 | Increased lipid droplet area | 3.343017511 | 19067489 | |
| Lipid storage | RpL6 | none | -2.692218569 | 19067489 | |
| Lipid storage | RpL6 | none | 0.719052009 | 19067489 | |
| ERK signaling | RpL6 | ERK activation reduced | weak | 17086199 | |
| Drosophila C virus infection | RpL6 | Drosophila C virus replication down | np | 17040126 | |
| Drosophila C virus infection | RpL6 | Drosophila C virus infection reduced | np | 15713840 | |
| Hedgehog signaling | RpL6 | Decreased Hedgehog reporter activity | -3 | 16311596 | |
| Constitutive protein secretion and Golgi organization (1) | RpL6 | Decreased horseradish peroxidase protein expression | sp | 16452979 | |
| Cell size and cell-cycle regulation (1) | RpL6 | Decreased viability | sp | 16496002 | |
| Cell size and cell-cycle regulation (2) | RpL6 | none | 1.087 | 16496002 | |
| Cell size and cell-cycle regulation (3) | RpL6 | none | 468 | 16496002 | |
| Lipid storage | RpL6 | More dispersed droplets | strong (but ribosomal) | 18408709 | |
| Combinatorial effect with methyl methanesulphonate (1) | RpL6 | none | sp | 19543366 | |
| Combinatorial effect with methyl methanesulphonate (2) | RpL6 | Synthetic lethal with methyl methanesulphonate | sp | 19543366 | |
| Heat nociception (1) | RpL6 | Lethal | -0.6 | 21074052 | |
| Heat nociception (1) | RpL6 | Developmentally lethal | 0 | 21074052 | |
| Heart development and function (1) | RpL6 | Larval lethal | 0.19 | 20371351 | |
| Notch induced transcription | RpL6 | none | -0.040967 | N(delta)ecn Notch stimulation | 20959007 |
| Notch induced transcription | RpL6 | Upregulation of Notch pathway after Notch stimulation | 2.116 | N(delta)ecn Notch stimulation | 20959007 |
| Notch induced transcription | RpL6 | none | -1.4553 | without Notch stimulation | 20959007 |
| Hh pathway regulation | RpL6 | Downregulation of Hh pathway | -0.446201851491092 | 17903264 | |
| Hh pathway regulation | RpL6 | Downregulation of Hh pathway | -0.385313587544595 | 17903264 | |
| Notch pathway regulation (1) | RpL6 | Downregulation of Notch pathway | np | 20493818 | |
| Blood cell homeostasis regulation (1) | RpL6 | Increased melanotic mass formation | np | 20540764 | |
| Blood cell homeostasis regulation (2) | RpL6 | none | np | 20540764 | |
| Blood cell homeostasis regulation (3) | RpL6 | none | 4.8 | 20540764 | |
| Blood cell homeostasis regulation (4) | RpL6 | Increased melanotic mass formation | 6.7 | 20540764 | |
| Blood cell homeostasis regulation (5) | RpL6 | none | 0 | 20540764 | |
| Blood cell homeostasis regulation (6) | RpL6 | Lethal | np | 20540764 |
