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Gene : Jra D. melanogaster

DB identifier  ? FBgn0001291 Secondary Identifier  ? CG2275
Name  ? Jun-related antigen Source  FlyBase
  • synonyms:
  • Jun oncogene,
  • JUN,
  • dJRA,
  • lethal(2)IA109,
  • FBgn0017591,
  • l(2)IA109,
  • V,
  • l(2R)IA109,
  • JRA,
  • FBgn0002124,
  • Complementation group V,
  • AP-1,
  • AP1,
  • activator protein 1,
  • DJUN,
  • FBgn0023037,
  • c-Jun,
  • FBan0002275,
  • dm-Jun,
  • D-jun/Jra,
  • FBgn0001291,
  • lethal(2)1A109,
  • D-Jun,
  • CG2275,
  • l(2)46Ef,
  • Jun related antigen,
  • dAP-1,
  • cJun,
  • d-JRA,
  • FBgn0015487

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32 Alleles

DB identifier Symbol Allele Class Organism
FBal0280556 Jra[DN.Scer\UAS]   Drosophila melanogaster
FBal0282351 Jra[JF01379]   Drosophila melanogaster
FBal0245476 Jra[JF01184]   Drosophila melanogaster
FBal0215807 Jra[Jbz.Scer\UAS] antimorphic allele - genetic evidence Drosophila melanogaster
FBal0215808 Jra[dsRNA.cBa.Scer\UAS]   Drosophila melanogaster
FBal0285730 Jra[T:Avic\GFP-SF,T:Zzzz\FLAG]   Drosophila melanogaster
FBal0048826 Jra[Ala.hs.sev] antimorphic allele - genetic evidence Drosophila melanogaster
FBal0048828 Jra[Asp.hs.sev]   Drosophila melanogaster
FBal0048830 Jra[hs.sev]   Drosophila melanogaster
FBal0052259 Jra[S82D.T92D.T107D.hs.sev]   Drosophila melanogaster
FBal0052261 Jra[S82A.T92A.T107A.hs.sev]   Drosophila melanogaster
FBal0118447 Jra[3]   Drosophila melanogaster
FBal0063162 Jra[+t5.2]   Drosophila melanogaster
FBal0119472 Jra[RC46]   Drosophila melanogaster
FBal0124162 Jra[dsRNA.cNa]   Drosophila melanogaster
FBal0063161 Jra[1] loss of function allele Drosophila melanogaster
FBal0043601 Jra[76-19] amorphic allele - genetic evidence Drosophila melanogaster
FBal0123146 Jra[cRa]   Drosophila melanogaster
FBal0009252 Jra[IA109] loss of function allele, amorphic allele - genetic evidence Drosophila melanogaster
FBal0052266 Jra[AD.hs.sev.T:Hsim\VP16]   Drosophila melanogaster
FBal0117716 Jra[Ala.B.Scer\UAS]   Drosophila melanogaster
FBal0117715 Jra[Asp.B.Scer\UAS]   Drosophila melanogaster
FBal0060636 Jra[Asp.Scer\UAS]   Drosophila melanogaster
FBal0033766 Jra[bZIP.hs.sev.T:Ivir\HA1] antimorphic allele - genetic evidence Drosophila melanogaster
FBal0160270 Jra[dsRNA.Scer\UAS]   Drosophila melanogaster
FBal0033767 Jra[fl.hs.sev.T:Ivir\HA1]   Drosophila melanogaster
FBal0060634 Jra[Scer\UAS.cEa]   Drosophila melanogaster
FBal0190267 Jra[Scer\UAS.T:Zzzz\TAP]   Drosophila melanogaster
FBal0194184 Jra[hs.T:Ecol\dam,T:Hsap\MYC]   Drosophila melanogaster
FBal0207427 Jra[GD4400]   Drosophila melanogaster

39 Clones

Secondary Identifier DB identifier
AT10175 FBcl0039579
AT04509 FBcl0039587
AT09868 FBcl0039589
EK197422 FBcl0085308
EN08208 FBcl0100819
EN06339 FBcl0100821
EN17560 FBcl0100823
EN00659 FBcl0100827
EN08640 FBcl0100839
EK219338 FBcl0130878
EK057221 FBcl0130898
EK197556 FBcl0130948
GH28626 FBcl0133823
GH26769 FBcl0133837
GM17859 FBcl0147952
LD25202 FBcl0177002
RE11781 FBcl0232481
RE26731 FBcl0232784
RE24535 FBcl0232788
RE12112 FBcl0232825
RE26733 FBcl0232900
RH50828 FBcl0270340
SD26172 FBcl0290369
SD16936 FBcl0290374
SD20220 FBcl0290394
EC056139 FBcl0301862
Dmel_neb_004774_0619_0859 FBcl0376510
FGM317C02 FBcl0393311
572956 FBcl0438812
CK01.72A.F9 FBcl0446571

4 Exons

DB identifier Symbol
FBgn0001291:1 Jra:1
FBgn0001291:3 Jra:3
FBgn0001291:4 Jra:4
FBgn0001291:2 Jra:2

3 Transcripts

DB identifier Gene
FBtr0088410 Jra
FBtr0330606 Jra
FBtr0088411 Jra

6 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0088410-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0088411-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0330606-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0088410-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0088411-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0330606-3-prime-utr Drosophila melanogaster

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82 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
36057 NCBI Entrez Gene identifiers FBgn0001291
61885 BioGRID FBgn0001291

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0001291 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1074.0
FBgn0001291 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 1254.0
FBgn0001291 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 776.0
FBgn0001291 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 703.0
FBgn0001291 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 926.0
FBgn0001291 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 608.0
FBgn0001291 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 1028.0
FBgn0001291 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 780.0
FBgn0001291 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 1102.0
FBgn0001291 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1065.0
FBgn0001291 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1053.0
FBgn0001291 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 537.0
FBgn0001291 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1111.0
FBgn0001291 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 730.0
FBgn0001291 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 806.0
FBgn0001291 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 745.0
FBgn0001291 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 770.0
FBgn0001291 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1046.0
FBgn0001291 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1163.0
FBgn0001291 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 858.0
FBgn0001291 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 885.0
FBgn0001291 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 1150.0
FBgn0001291 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 922.0
FBgn0001291 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1039.0
FBgn0001291 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1195.0
FBgn0001291 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 1129.0
FBgn0001291 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 305.0
FBgn0001291 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 279.0
FBgn0001291 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 288.0
FBgn0001291 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 373.0

3 Introns

DB identifier
Organism . Name
intron_FBgn0001291:1_FBgn0001291:3 Drosophila melanogaster
intron_FBgn0001291:3_FBgn0001291:4 Drosophila melanogaster
intron_FBgn0001291:2_FBgn0001291:4 Drosophila melanogaster

34 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Cell size regulation Jra none -3.21   19216764
Lipid storage Jra none -2.394016609   19067489
Lipid storage Jra none 0.067497703   19067489
Caspase activation in apoptosis (1) - combinatorial effect with doxorubicin Jra Increased viability with doxorubicin np   17998402
Caspase activation in apoptosis (2) - combinatorial effect with doxorubicin Jra Decreased caspase-3/7-like activity with doxorubicin np   17998402
ERK signaling Jra ERK activation increased strong   17086199
Cell size and cell-cycle regulation (1) Jra none sp   16496002
Candida albicans phagocytosis (1) Jra Decreased Candida albicans phagocytosis np   16336044
Candida albicans phagocytosis (2) Jra Decreased Escherichia coli phagocytosis 42   16336044
Candida albicans phagocytosis (3) Jra Decreased latex beads phagocytosis 31   16336044
Dendrite pattern formation Jra none np   16547170
Heat nociception (1) Jra none -0.4   21074052
Heart development and function (1) Jra none 1   20371351
Serratia marcescens infection (1) Jra none -0.870588235294117   19520911
Notch pathway regulation (4) Jra Planar polarity defects, notum malformation migration, overproliferation sp   19363474
Notch pathway regulation (1) Jra Upregulation of Notch pathway np   20493818
Notch pathway regulation (2) Jra Lethal strong en-GAL4 20493818
Notch pathway regulation (2) Jra Lethal very strong en-GAL4 20493818
Notch pathway regulation (2) Jra none np C96-GAL4 20493818
Notch pathway regulation (2) Jra Downregulation of Notch pathway; adult wing margin: notches sp C96-GAL4 20493818
Notch pathway regulation (2) Jra Downregulation of Notch pathway; wing disc NRE:EGFP: gap sp en-GAL4 20493818
Notch pathway regulation (2) Jra Downregulation of Notch pathway; wing disc NRE:EGFP: up, down, broader, gap; lethal sp en-GAL4 20493818
Notch pathway regulation (3) Jra Only lethal with Notch np   20493818
Adiposity regulation (1) Jra none 0.564   20074523
Blood cell homeostasis regulation (1) Jra none np   20540764
Blood cell homeostasis regulation (2) Jra none np   20540764
RTK-Ras-ERK pathway regulation (1) Jra Increased ERK phosphorylation after EGF stimulation 2.62 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) Jra Increased ERK phosphorylation after EGF stimulation 1.51 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Jra none -0.28 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Jra none -1.13 30 minutes sSpitz stimulation 22028469

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