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Gene : Aos1 D. melanogaster

DB identifier  ? FBgn0029512 Secondary Identifier  ? CG12276
Name  ? Aos1 Source  FlyBase
  • synonyms:
  • DmSAE1,
  • Ubiquitin activating enzyme,
  • AOS1,
  • Ubiquitin activating enzyme 1,
  • CG12276,
  • SAE1,
  • Smt3 activating enzyme 1,
  • FBgn0038048,
  • DmAos1,
  • FBan0012276,
  • FBgn0029512,
  • Aos,
  • FBgn0040288

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13 Alleles

DB identifier Symbol Allele Class Organism
FBal0276841 Aos1[+t2.9]   Drosophila melanogaster
FBal0276842 Aos1[Scer\UAS.cKa]   Drosophila melanogaster
FBal0276843 Aos1[N1] amorphic allele - molecular evidence Drosophila melanogaster
FBal0276844 Aos1[N2] amorphic allele - molecular evidence Drosophila melanogaster
FBal0240312 Aos1[HM05183]   Drosophila melanogaster
FBal0249066 Aos1[VDRC.cUa]   Drosophila melanogaster
FBal0162805 Aos1[c06048] amorphic allele - molecular evidence Drosophila melanogaster
FBal0262958 Aos1[GL00493]   Drosophila melanogaster
FBal0103992 Aos1[Act5C.T:Ivir\HA1]   Drosophila melanogaster
FBal0193265 Aos1[t2]   Drosophila melanogaster
FBal0198733 Aos1[GD8542]   Drosophila melanogaster
FBal0198734 Aos1[GD16818]   Drosophila melanogaster
FBal0271193 Aos1[NIG.12276R]   Drosophila melanogaster

32 Clones

Secondary Identifier DB identifier
UUGC0909 FBcl0005051
EK138743 FBcl0026060
EK213345 FBcl0026078
AT28746 FBcl0046333
bs04c10 FBcl0058739
EC02931 FBcl0073595
GM10027 FBcl0143828
LD11809 FBcl0161309
LD13875 FBcl0161319
LD33652 FBcl0175877
LD33653 FBcl0176818
LD26944 FBcl0176820
LP03158 FBcl0189858
LP05830 FBcl0189865
RE06666 FBcl0230958
RE34601 FBcl0232210
RE53513 FBcl0232217
RE34224 FBcl0232230
RE64294 FBcl0232282
RE54092 FBcl0232438
RE05858 FBcl0232446
SD22888 FBcl0292384
SD16308 FBcl0292385
Dmel_neb_013673_0688_0618 FBcl0368901
Dmel_dig_010376_0603_3710 FBcl0368903
FGM238G06 FBcl0392133
FGM322D12 FBcl0393697
562028 FBcl0456170
DPiM_LD33652 FBcl0738664
30189 FBcl0453819

3 Exons

DB identifier Symbol
FBgn0029512:3 Aos1:3
FBgn0029512:2 Aos1:2
FBgn0029512:1 Aos1:1

1 Transcripts

DB identifier Gene
FBtr0082593 Aos1

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0082593-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0082593-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
41532 NCBI Entrez Gene identifiers FBgn0029512
66630 BioGRID FBgn0029512

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0029512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 2199.0
FBgn0029512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 2333.0
FBgn0029512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1532.0
FBgn0029512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 2351.0
FBgn0029512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 2232.0
FBgn0029512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 1492.0
FBgn0029512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 1307.0
FBgn0029512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 1779.0
FBgn0029512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 1016.0
FBgn0029512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 2118.0
FBgn0029512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 2073.0
FBgn0029512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 1757.0
FBgn0029512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1545.0
FBgn0029512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 2086.0
FBgn0029512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 2172.0
FBgn0029512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 2189.0
FBgn0029512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1640.0
FBgn0029512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1317.0
FBgn0029512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 2408.0
FBgn0029512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1696.0
FBgn0029512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 1825.0
FBgn0029512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 1946.0
FBgn0029512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 1693.0
FBgn0029512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1414.0
FBgn0029512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1211.0
FBgn0029512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 4706.0
FBgn0029512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 4320.0
FBgn0029512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 3293.0
FBgn0029512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 2314.0
FBgn0029512 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1497.0

2 Introns

DB identifier
Organism . Name
intron_FBgn0029512:3_FBgn0029512:2 Drosophila melanogaster
intron_FBgn0029512:2_FBgn0029512:1 Drosophila melanogaster

32 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Aos1 none 0.981409071   19067489
Lipid storage Aos1 none 4.554595312   19067489
Cell size and cell-cycle regulation (1) Aos1 none sp   16496002
Muscle morphogenesis and function (1) Aos1 Flightless np   20220848
Muscle morphogenesis and function (1) Aos1 Flightless np   20220848
Muscle morphogenesis and function (4) Aos1 none np   20220848
Heat nociception (1) Aos1 none -0.8   21074052
Heat nociception (1) Aos1 none 1.21   21074052
Heart development and function (1) Aos1 none 1   20371351
Serratia marcescens infection (1) Aos1 none 0.283783783783783   19520911
Serratia marcescens infection (1) Aos1 Decreased viability after Serratia marcescens infection -1.77358490566037   19520911
Serratia marcescens infection (2) Aos1 none sp   19520911
Serratia marcescens infection (4) Aos1 none sp   19520911
Serratia marcescens infection (5) Aos1 Viable np   19520911
Notch pathway regulation (4) Aos1 Completely lethal (pupal) sp   19363474
Notch pathway regulation (4) Aos1 Notum malformation death 9   19363474
Notch pathway regulation (4) Aos1 Completely lethal (pupal) sp   19363474
Self-renewal and differentiation in neural stem cells Aos1 GFP aggregates number, GFP aggregates size, neuroblast larger cell size, neuroblast less large cells, neuroblast cell shape, ganglion mother cell shorter lineages, ganglion mother cell shape, neuroblast loss, neuroblast loss with larger neuroblast cell si sp   21549331
Adiposity regulation (1) Aos1 none -0.191   20074523
Adiposity regulation (1) Aos1 none -0.086   20074523
Blood cell homeostasis regulation (1) Aos1 Increased melanotic mass formation np   20540764
Blood cell homeostasis regulation (2) Aos1 none np   20540764
Blood cell homeostasis regulation (3) Aos1 none 0   20540764
Blood cell homeostasis regulation (4) Aos1 Increased melanotic mass formation 10   20540764
Blood cell homeostasis regulation (5) Aos1 Increased melanotic mass formation 56.4   20540764
Blood cell homeostasis regulation (6) Aos1 none 1.9   20540764
Blood cell homeostasis regulation (7) Aos1 Increased melanotic mass formation 21.6   20540764
Blood cell homeostasis regulation (8) Aos1 Increased melanotic mass formation 22.9   20540764
Wnt proteins secretion Aos1 none 0.3   22094269
Hippo pathway regulation Aos1 none 0.06   23263283

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