Genomics
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7 Alleles
| DB identifier | Symbol | Allele Class | Organism |
|---|---|---|---|
| FBal0270246 | Lst8[1] | amorphic allele - genetic evidence | Drosophila melanogaster |
| FBal0270247 | Lst8[3] | amorphic allele - genetic evidence | Drosophila melanogaster |
| FBal0270248 | Lst8[Scer\UAS.cWa] | Drosophila melanogaster | |
| FBal0270249 | Lst8[Scer\UAS.T:Zzzz\FLAG] | Drosophila melanogaster | |
| FBal0235810 | Lst8[KK108778] | Drosophila melanogaster | |
| FBal0202424 | Lst8[GD9976] | Drosophila melanogaster | |
| FBal0257943 | Lst8[HMS01350] | Drosophila melanogaster |
34 Clones
2 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0071368-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0071368-3-prime-utr | Drosophila melanogaster |
Other
54 Pathways
- Fc epsilon receptor (FCERI) signaling,
- Downstream signal transduction,
- IRS-related events,
- Release of eIF4E,
- Role of LAT2/NTAL/LAB on calcium mobilization,
- PI3K Cascade,
- Insulin signaling pathway,
- IRS-related events triggered by IGF1R,
- Signaling by ERBB4,
- Costimulation by the CD28 family,
- DAP12 signaling,
- DINR-mediated activation,
- CD28 dependent PI3K/Akt signaling,
- Disease,
- Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R),
- Signaling by SCF-KIT,
- B Cell Activation,
- Signaling by ERBB2,
- mTORC1-mediated signalling,
- Regulation of Rheb GTPase activity by AMPK,
- PI3K events in ERBB2 signaling,
- Insulin receptor signalling cascade,
- Signaling by EGFR,
- Signaling Pathways,
- Downstream Signaling Events Of B Cell Receptor (BCR),
- PI3K/AKT Signaling in Cancer,
- PI3K events in ERBB4 signaling,
- PI3K/AKT activation,
- Insulin receptor mediated signaling,
- Insulin receptor recycling,
- PIP3 activates AKT signaling,
- Regulation of AMPK activity via LKB1,
- IRS activation,
- PI-3K cascade,
- Signaling by NGF,
- Signaling by FGFR,
- Signaling by FGFR in disease,
- Immune System,
- NGF signalling via TRKA from the plasma membrane,
- CD28 co-stimulation,
- DAP12 interactions,
- Signaling by PDGF,
- mTOR signalling,
- Innate Immune System,
- IRS-mediated signalling,
- Downstream signaling of activated FGFR,
- GAB1 signalosome,
- Adaptive Immune System,
- Signaling by EGFR in Cancer,
- IGF1R signaling cascade,
- PKB-mediated events,
- Constitutive PI3K/AKT Signaling in Cancer,
- Energy dependent regulation of mTOR by LKB1-AMPK,
- TOR signaling pathway
2 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 31903 | NCBI Entrez Gene identifiers | FBgn0264691 |
| 58343 | BioGRID | FBgn0264691 |
10 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| Swiss-Prot data set | http://ca.expasy.org/sprot |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| IntAct interactions data set | |
| BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster |
25 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Lipid storage | Lst8 | none | -0.021014545 | 19067489 | |
| Lipid storage | Lst8 | none | -0.079931027 | 19067489 | |
| Lipid storage | Lst8 | none | 0.432398098 | 19067489 | |
| Lipid storage | Lst8 | none | 0.000875241 | 19067489 | |
| Cell size and cell-cycle regulation (1) | Lst8 | none | sp | 16496002 | |
| Combinatorial effect with methyl methanesulphonate (1) | Lst8 | none | sp | 19543366 | |
| Muscle morphogenesis and function (1) | Lst8 | none | np | 20220848 | |
| Muscle morphogenesis and function (1) | Lst8 | none | np | 20220848 | |
| Heat nociception (1) | Lst8 | Developmentally lethal | 0 | 21074052 | |
| Heart development and function (1) | Lst8 | none | 1 | 20371351 | |
| Serratia marcescens infection (1) | Lst8 | none | 0.208333333333333 | 19520911 | |
| Serratia marcescens infection (1) | Lst8 | none | 1.05882352941176 | 19520911 | |
| Notch pathway regulation (4) | Lst8 | none | 0 | 19363474 | |
| Notch pathway regulation (4) | Lst8 | none | 0 | 19363474 | |
| Akt-TOR pathway negative feedback regulation | Lst8 | Decreased dAkt phosphorylation after insulin stimulation | -4.3 | 10 min insulin stimulation | 20585550 |
| Adiposity regulation (1) | Lst8 | Increased triglyceride expression | 0.133 | 20074523 | |
| Adiposity regulation (1) | Lst8 | none | 0.506 | 20074523 | |
| Adiposity regulation (2) | Lst8 | Decreased triglyceride expression | -0.256 | 20074523 | |
| Adiposity regulation (3) | Lst8 | none | 0.027 | 20074523 | |
| Adiposity regulation (4) | Lst8 | Increased triglyceride expression | 0.303 | 20074523 | |
| Adiposity regulation (5) | Lst8 | none | -0.079 | 20074523 | |
| Blood cell homeostasis regulation (1) | Lst8 | none | np | 20540764 | |
| Blood cell homeostasis regulation (2) | Lst8 | none | np | 20540764 | |
| Hippo pathway regulation | Lst8 | none | 0.72 | 23263283 | |
| Glycosylation regulation (1) | Lst8 | none | sp | 21203496 |
