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Gene : lkb1 D. melanogaster

DB identifier  ? FBgn0038167 Secondary Identifier  ? CG9374
Name  ? lkb1 Source  FlyBase
  • synonyms:
  • DmLKB1,
  • LKB1,
  • PAR4,
  • dLKB1,
  • FBgn0045844,
  • PAR-4,
  • FBgn0038167,
  • anon-EST:Posey135,
  • LKB1/PEUTZ JEGHERS KINASE,
  • CG9374,
  • FBan0009374,
  • FBgn0027757,
  • STK11

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28 Alleles

DB identifier Symbol Allele Class Organism
FBal0141056 lkb1[T:Avic\GFP]   Drosophila melanogaster
FBal0258421 lkb1[GS11006]   Drosophila melanogaster
FBal0265787 lkb1[Scer\UAS.cWa]   Drosophila melanogaster
FBal0265788 lkb1[dsRNA.Scer\UAS.cWa]   Drosophila melanogaster
FBal0257944 lkb1[HMS01351]   Drosophila melanogaster
FBal0213122 lkb1[X5] loss of function allele Drosophila melanogaster
FBal0213123 lkb1[Scer\UAS.cLa]   Drosophila melanogaster
FBal0141053 lkb1[4B1-11]   Drosophila melanogaster
FBal0141055 lkb1[+tMa]   Drosophila melanogaster
FBal0141049 lkb1[S535A.MtnA]   Drosophila melanogaster
FBal0141050 lkb1[MtnA.PM]   Drosophila melanogaster
FBal0141054 lkb1[4A4-2]   Drosophila melanogaster
FBal0141045 lkb1[unspecified]   Drosophila melanogaster
FBal0262510 lkb1[GL00019]   Drosophila melanogaster
FBal0141052 lkb1[C537A.Scer\UAS.P\T.T:Avic\GFP]   Drosophila melanogaster
FBal0141051 lkb1[K147M.Scer\UAS.P\T.T:Avic\GFP]   Drosophila melanogaster
FBal0141048 lkb1[S535A.Scer\UAS.P\T.T:Avic\GFP]   Drosophila melanogaster
FBal0141047 lkb1[S535E.Scer\UAS.P\T.T:Avic\GFP]   Drosophila melanogaster
FBal0141046 lkb1[Scer\UAS.P\T.T:Avic\GFP]   Drosophila melanogaster
FBal0230261 lkb1[K201I.Scer\UAS]   Drosophila melanogaster
FBal0215014 lkb1[GD14203]   Drosophila melanogaster
FBal0217762 lkb1[315] amorphic allele - genetic evidence Drosophila melanogaster
FBal0217763 lkb1[7]   Drosophila melanogaster
FBal0217764 lkb1[+tBa]   Drosophila melanogaster
FBal0230518 lkb1[dsRNA.Scer\UAS]   Drosophila melanogaster
FBal0241588 lkb1[G5285]   Drosophila melanogaster
FBal0230517 lkb1[EP-1]   Drosophila melanogaster
FBal0235732 lkb1[KK108675]   Drosophila melanogaster

146 Clones

Secondary Identifier DB identifier
DPiM_GM01569 FBcl0741063
AF171810 FBcl0000237
EK249046 FBcl0017164
AT01790 FBcl0044083
AT18737 FBcl0044085
AT11831 FBcl0044091
AT26916 FBcl0044095
AT15173 FBcl0044097
AT24005 FBcl0044099
AT08078 FBcl0044101
AT01650 FBcl0044103
AT18543 FBcl0044105
AT21909 FBcl0044107
AT03842 FBcl0044109
AT14701 FBcl0044111
AT12391 FBcl0044113
AT18994 FBcl0044115
AT29369 FBcl0044117
AT01168 FBcl0044119
AT26824 FBcl0044121
AT27805 FBcl0044123
AT19225 FBcl0044127
AT26131 FBcl0044129
AT06268 FBcl0044131
AT20439 FBcl0044133
AT11338 FBcl0044135
AT17668 FBcl0044137
AT12057 FBcl0044139
AT19160 FBcl0044141
AT15012 FBcl0044143

12 Exons

DB identifier Symbol
FBgn0038167:1 lkb1:1
FBgn0038167:4 lkb1:4
FBgn0038167:6 lkb1:6
FBgn0038167:7 lkb1:7
FBgn0038167:8 lkb1:8
FBgn0038167:11 lkb1:11
FBgn0038167:3 lkb1:3
FBgn0038167:5 lkb1:5
FBgn0038167:2 lkb1:2
FBgn0038167:12 lkb1:12
FBgn0038167:10 lkb1:10
FBgn0038167:9 lkb1:9

9 Transcripts

DB identifier Gene
FBtr0082812 lkb1
FBtr0082808 lkb1
FBtr0082814 lkb1
FBtr0301488 lkb1
FBtr0082815 lkb1
FBtr0082810 lkb1
FBtr0082811 lkb1
FBtr0082813 lkb1
FBtr0082809 lkb1

18 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0082812-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0082813-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0082814-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0082815-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0082808-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0082809-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0082810-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0082811-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0301488-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0082812-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0082813-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0082814-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0082815-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0082808-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0082809-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0082810-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0082811-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0301488-3-prime-utr Drosophila melanogaster

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1 Cross References

Identifier
Source . Name

Subject . Primary Identifier
41673 NCBI Entrez Gene identifiers FBgn0038167

10 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0038167 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 711.0
FBgn0038167 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 617.0
FBgn0038167 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 861.0
FBgn0038167 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 635.0
FBgn0038167 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 746.0
FBgn0038167 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 405.0
FBgn0038167 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 392.0
FBgn0038167 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 824.0
FBgn0038167 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 294.0
FBgn0038167 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 551.0
FBgn0038167 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 563.0
FBgn0038167 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 430.0
FBgn0038167 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 519.0
FBgn0038167 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 622.0
FBgn0038167 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 372.0
FBgn0038167 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 629.0
FBgn0038167 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 429.0
FBgn0038167 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 536.0
FBgn0038167 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 472.0
FBgn0038167 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 374.0
FBgn0038167 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 567.0
FBgn0038167 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 827.0
FBgn0038167 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 367.0
FBgn0038167 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 211.0
FBgn0038167 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 378.0
FBgn0038167 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 1151.0
FBgn0038167 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 762.0
FBgn0038167 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 307.0
FBgn0038167 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 368.0
FBgn0038167 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 236.0

12 Introns

DB identifier
Organism . Name
intron_FBgn0038167:1_FBgn0038167:4 Drosophila melanogaster
intron_FBgn0038167:4_FBgn0038167:6 Drosophila melanogaster
intron_FBgn0038167:6_FBgn0038167:7 Drosophila melanogaster
intron_FBgn0038167:7_FBgn0038167:8 Drosophila melanogaster
intron_FBgn0038167:8_FBgn0038167:11 Drosophila melanogaster
intron_FBgn0038167:3_FBgn0038167:5 Drosophila melanogaster
intron_FBgn0038167:5_FBgn0038167:6 Drosophila melanogaster
intron_FBgn0038167:2_FBgn0038167:4 Drosophila melanogaster
intron_FBgn0038167:3_FBgn0038167:4 Drosophila melanogaster
intron_FBgn0038167:8_FBgn0038167:12 Drosophila melanogaster
intron_FBgn0038167:8_FBgn0038167:10 Drosophila melanogaster
intron_FBgn0038167:7_FBgn0038167:9 Drosophila melanogaster

16 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage lkb1 none -3.176510718   19067489
Lipid storage lkb1 none 1.638333058   19067489
Cell cycle regulation (1) lkb1 All mitotic defects, centrosome defects, spindle defects sp   15616552
Cell cycle regulation (2) lkb1 none np   15616552
Cell size and cell-cycle regulation (1) lkb1 none sp   16496002
Cell size and cell-cycle regulation (1) lkb1 none sp   16496002
Combinatorial effect with methyl methanesulphonate (2) lkb1 none sp   19543366
PGN-induced dJNK phosphorylation lkb1 Increased P-JNK protein expression with PGN 2.02 15 min PGN induction 19893628
Actin organization and cell morphology (1) lkb1 none np   19265526
Actin organization and cell morphology (2) lkb1 none np   19265526
Actin organization and cell morphology (3) lkb1 none np   19265526
Actin organization and cell morphology (4) lkb1 none np   19265526
Actin organization and cell morphology (5) lkb1 none np   19265526
Actin organization and cell morphology (6) lkb1 none np   19265526
Vaccinia virus infection lkb1 none sp   20585561
Hippo pathway regulation lkb1 none -0.16   23263283

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