Genomics
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28 Alleles
146 Clones
12 Exons
DB identifier | Symbol |
---|---|
FBgn0038167:1 | lkb1:1 |
FBgn0038167:4 | lkb1:4 |
FBgn0038167:6 | lkb1:6 |
FBgn0038167:7 | lkb1:7 |
FBgn0038167:8 | lkb1:8 |
FBgn0038167:11 | lkb1:11 |
FBgn0038167:3 | lkb1:3 |
FBgn0038167:5 | lkb1:5 |
FBgn0038167:2 | lkb1:2 |
FBgn0038167:12 | lkb1:12 |
FBgn0038167:10 | lkb1:10 |
FBgn0038167:9 | lkb1:9 |
9 Transcripts
DB identifier | Gene |
---|---|
FBtr0082812 | lkb1 |
FBtr0082808 | lkb1 |
FBtr0082814 | lkb1 |
FBtr0301488 | lkb1 |
FBtr0082815 | lkb1 |
FBtr0082810 | lkb1 |
FBtr0082811 | lkb1 |
FBtr0082813 | lkb1 |
FBtr0082809 | lkb1 |
18 UTRs
Other
24 Pathways
- Regulation of Rheb GTPase activity by AMPK,
- Energy dependent regulation of mTOR by LKB1-AMPK,
- IGF1R signaling cascade,
- PKB-mediated events,
- Insulin signaling pathway,
- Insulin receptor recycling,
- IRS activation,
- Metabolism,
- Insulin receptor mediated signaling,
- IRS-mediated signalling,
- mTOR signalling,
- IRS-related events,
- Signaling Pathways,
- Insulin receptor signalling cascade,
- AMPK inhibits chREBP transcriptional activation activity,
- Integration of energy metabolism,
- Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R),
- TOR signaling pathway,
- mTORC1-mediated signalling,
- Release of eIF4E,
- IRS-related events triggered by IGF1R,
- PI3K Cascade,
- DINR-mediated activation,
- Regulation of AMPK activity via LKB1
1 Cross References
Identifier |
Source . Name |
Subject . Primary Identifier |
---|---|---|
41673 | NCBI Entrez Gene identifiers | FBgn0038167 |
10 Data Sets
Name | URL |
---|---|
FlyBase data set for Drosophila melanogaster | |
TrEMBL data set | http://www.ebi.ac.uk/trembl/ |
Drosophila 12 Genomes Consortium homology | |
GenomeRNAi data set | |
TreeFam data set | |
Panther data set | |
IntAct interactions data set | |
GO Annotation from FlyBase | |
FlyBase fasta data set for Drosophila melanogaster | |
Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
12 Introns
16 RNAi Results
Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
---|---|---|---|---|---|
Lipid storage | lkb1 | none | -3.176510718 | 19067489 | |
Lipid storage | lkb1 | none | 1.638333058 | 19067489 | |
Cell cycle regulation (1) | lkb1 | All mitotic defects, centrosome defects, spindle defects | sp | 15616552 | |
Cell cycle regulation (2) | lkb1 | none | np | 15616552 | |
Cell size and cell-cycle regulation (1) | lkb1 | none | sp | 16496002 | |
Cell size and cell-cycle regulation (1) | lkb1 | none | sp | 16496002 | |
Combinatorial effect with methyl methanesulphonate (2) | lkb1 | none | sp | 19543366 | |
PGN-induced dJNK phosphorylation | lkb1 | Increased P-JNK protein expression with PGN | 2.02 | 15 min PGN induction | 19893628 |
Actin organization and cell morphology (1) | lkb1 | none | np | 19265526 | |
Actin organization and cell morphology (2) | lkb1 | none | np | 19265526 | |
Actin organization and cell morphology (3) | lkb1 | none | np | 19265526 | |
Actin organization and cell morphology (4) | lkb1 | none | np | 19265526 | |
Actin organization and cell morphology (5) | lkb1 | none | np | 19265526 | |
Actin organization and cell morphology (6) | lkb1 | none | np | 19265526 | |
Vaccinia virus infection | lkb1 | none | sp | 20585561 | |
Hippo pathway regulation | lkb1 | none | -0.16 | 23263283 |