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Gene : ImpL3 D. melanogaster

DB identifier  ? FBgn0001258 Secondary Identifier  ? CG10160
Name  ? Ecdysone-inducible gene L3 Source  FlyBase
  • synonyms:
  • FBan0010160,
  • FBgn0001258,
  • Ecdysone-induced gene L3,
  • dmLDH,
  • IMPL3,
  • dLDH,
  • lactate dehydrogenase,
  • IMP-L3,
  • FBgn0035698,
  • Ld,
  • LDH,
  • lactic DH,
  • lactate/malate dehydrogenease,
  • lactate dehydrogenase B,
  • CG10160,
  • dLdha

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4 Alleles

DB identifier Symbol Allele Class Organism
FBal0257081 ImpL3[HMS00039]   Drosophila melanogaster
FBal0259161 ImpL3[KK102330]   Drosophila melanogaster
FBal0270351 ImpL3[NIG.10160R]   Drosophila melanogaster
FBal0207381 ImpL3[GD6887]   Drosophila melanogaster

76 Clones

Secondary Identifier DB identifier
DPiM_FI09306 FBcl0740854
UUGC1003 FBcl0005391
EK063541 FBcl0059600
EK189346 FBcl0059622
EK230445 FBcl0059646
EK165428 FBcl0059698
EK118414 FBcl0059724
EK194853 FBcl0059748
EK046831 FBcl0059826
EK215462 FBcl0059850
EK143137 FBcl0060334
EC33837 FBcl0066321
EP10140 FBcl0080573
EN05325 FBcl0095093
EN12934 FBcl0095159
EN16020 FBcl0096563
GH08068 FBcl0107497
GH15536 FBcl0107533
GM29479 FBcl0145758
LD20346 FBcl0152573
LP14415 FBcl0181060
LP10507 FBcl0181072
LP19712 FBcl0181074
LP09531 FBcl0181090
RE71158 FBcl0198195
RE37072 FBcl0198385
RE64758 FBcl0198400
RE70018 FBcl0198402
RE58815 FBcl0198458
RE54418 FBcl0198496

7 Exons

DB identifier Symbol
FBgn0001258:6 ImpL3:6
FBgn0001258:2 ImpL3:2
FBgn0001258:1 ImpL3:1
FBgn0001258:5 ImpL3:5
FBgn0001258:7 ImpL3:7
FBgn0001258:4 ImpL3:4
FBgn0001258:3 ImpL3:3

4 Transcripts

DB identifier Gene
FBtr0332067 ImpL3
FBtr0332066 ImpL3
FBtr0077008 ImpL3
FBtr0332065 ImpL3

8 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0077008-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0332065-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0332066-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0332067-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0077008-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0332065-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0332066-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0332067-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
45880 NCBI Entrez Gene identifiers FBgn0001258
69949 BioGRID FBgn0001258

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0001258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1380.0
FBgn0001258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 532.0
FBgn0001258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 677.0
FBgn0001258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1530.0
FBgn0001258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1247.0
FBgn0001258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 3188.0
FBgn0001258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 2418.0
FBgn0001258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 1301.0
FBgn0001258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 1084.0
FBgn0001258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1385.0
FBgn0001258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 790.0
FBgn0001258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 411.0
FBgn0001258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 780.0
FBgn0001258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 215.0
FBgn0001258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 4087.0
FBgn0001258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 4220.0
FBgn0001258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 5715.0
FBgn0001258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 3675.0
FBgn0001258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 2572.0
FBgn0001258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 3610.0
FBgn0001258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 3847.0
FBgn0001258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 181.0
FBgn0001258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 2229.0
FBgn0001258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 5311.0
FBgn0001258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 2293.0
FBgn0001258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 115.0
FBgn0001258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 174.0
FBgn0001258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 189.0
FBgn0001258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 240.0
FBgn0001258 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 379.0

6 Introns

DB identifier
Organism . Name
intron_FBgn0001258:7_FBgn0001258:4 Drosophila melanogaster
intron_FBgn0001258:4_FBgn0001258:3 Drosophila melanogaster
intron_FBgn0001258:3_FBgn0001258:2 Drosophila melanogaster
intron_FBgn0001258:3_FBgn0001258:1 Drosophila melanogaster
intron_FBgn0001258:5_FBgn0001258:4 Drosophila melanogaster
intron_FBgn0001258:6_FBgn0001258:4 Drosophila melanogaster

17 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage ImpL3 none 0.980541703   19067489
Lipid storage ImpL3 none 0.97855676   19067489
Cell size and cell-cycle regulation (1) ImpL3 none sp   16496002
Cell size and cell-cycle regulation (1) ImpL3 none sp   16496002
Muscle morphogenesis and function (1) ImpL3 none np   20220848
Heat nociception (1) ImpL3 none -0.36   21074052
Heart development and function (1) ImpL3 none 1   20371351
Serratia marcescens infection (1) ImpL3 none -0.655555555555555   19520911
Notch pathway regulation (4) ImpL3 none 0   19363474
PGN-induced dJNK phosphorylation ImpL3 Decreased P-JNK protein expression with PGN -3.41 15 min PGN induction 19893628
Notch pathway regulation (3) ImpL3 none np   20493818
Secretory pathway regulation ImpL3 Decreased BiP signal peptide and firefly luciferase fusion protein expression (-2) - (-1.5)   19942856
RTK-Ras-ERK pathway regulation (1) ImpL3 Increased ERK phosphorylation after EGF stimulation 1.72 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) ImpL3 none 0.35 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) ImpL3 none -0.15 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) ImpL3 none 0.16 30 minutes sSpitz stimulation 22028469
Hippo pathway regulation ImpL3 none -1.32   23263283

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