Genomics
Gene Ontology Displayer
Homologue Displayer
Mod Mine G Browse Displayer
Overlapping Features Displayer
Regulatory Regions Displayer
9 Alleles
| DB identifier | Symbol | Allele Class | Organism |
|---|---|---|---|
| FBal0241450 | shtd[2] | Drosophila melanogaster | |
| FBal0241451 | shtd[3.gamma] | Drosophila melanogaster | |
| FBal0241453 | shtd[rescue.Scer\UAS] | Drosophila melanogaster | |
| FBal0258831 | shtd[KK100819] | Drosophila melanogaster | |
| FBal0140936 | shtd[1] | Drosophila melanogaster | |
| FBal0278862 | shtd[HMS01744] | Drosophila melanogaster | |
| FBal0287528 | shtd[Scer\UAS.ORF.T:Ivir\HA1] | Drosophila melanogaster | |
| FBal0210576 | shtd[GD14150] | Drosophila melanogaster | |
| FBal0198126 | shtd[3] | loss of function allele | Drosophila melanogaster |
11 Clones
| Secondary Identifier | DB identifier |
|---|---|
| DPiM_LD37115 | FBcl0740633 |
| DMG1-chrX.16.031.a | FBcl0361173 |
| EK286045 | FBcl0129248 |
| GM22507 | FBcl0144627 |
| GM29903 | FBcl0144629 |
| LD37115 | FBcl0171688 |
| RP004207999 | FBcl0503575 |
| CK01.14D.F7 | FBcl0435803 |
| 180906 | FBcl0435830 |
| 214565.29 | FBcl0435842 |
| 62021 | FBcl0435848 |
8 Exons
| DB identifier | Symbol |
|---|---|
| FBgn0004391:8 | shtd:8 |
| FBgn0004391:7 | shtd:7 |
| FBgn0004391:6 | shtd:6 |
| FBgn0004391:5 | shtd:5 |
| FBgn0004391:4 | shtd:4 |
| FBgn0004391:3 | shtd:3 |
| FBgn0004391:2 | shtd:2 |
| FBgn0004391:1 | shtd:1 |
2 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0074077-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0074077-3-prime-utr | Drosophila melanogaster |
Other
53 Pathways
- M Phase,
- Cell Cycle, Mitotic,
- Mitotic M-M/G1 phases,
- Regulation of mitotic cell cycle,
- p53-Independent DNA Damage Response,
- ATM mediated response to DNA double-strand break,
- Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase,
- G2/M Checkpoints,
- Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal,
- Mitotic G1-G1/S phases,
- Mitotic Anaphase,
- Phosphorylation of the APC/C,
- APC/C:Cdc20 mediated degradation of mitotic proteins,
- Inactivation of APC/C via direct inhibition of the APC/C complex,
- Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components,
- Homologous recombination repair of replication-independent double-strand breaks,
- Mitotic Metaphase and Anaphase,
- Mitotic Spindle Checkpoint,
- APC/C:Cdc20 mediated degradation of Cyclin B,
- Cyclin E associated events during G1/S transition,
- Mitotic G2-G2/M phases,
- Polo-like kinase mediated events,
- Cell Cycle Checkpoints,
- Homologous Recombination Repair,
- Senescence-Associated Secretory Phenotype (SASP),
- G2/M Transition,
- Regulation of APC/C activators between G1/S and early anaphase,
- Ubiquitin Mediated Degradation of Phosphorylated Cdc25A,
- G1/S DNA Damage Checkpoints,
- S Phase,
- APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1,
- Cellular responses to stress,
- Cyclin A:Cdk2-associated events at S phase entry,
- Amplification of signal from the kinetochores,
- Cell Cycle,
- p53-Independent G1/S DNA damage checkpoint,
- Cyclin A/B1 associated events during G2/M transition,
- Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex,
- Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins,
- Separation of Sister Chromatids,
- APC/C:Cdc20 mediated degradation of Securin,
- G2/M DNA damage checkpoint,
- APC-Cdc20 mediated degradation of Nek2A,
- DNA Repair,
- Cellular Senescence,
- G1/S Transition,
- Cdc20:Phospho-APC/C mediated degradation of Cyclin A,
- DNA Replication,
- APC/C-mediated degradation of cell cycle proteins,
- Double-Strand Break Repair,
- SCF(Skp2)-mediated degradation of p27/p21,
- Autodegradation of Cdh1 by Cdh1:APC/C,
- G2/M DNA replication checkpoint
2 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 32473 | NCBI Entrez Gene identifiers | FBgn0004391 |
| 58826 | BioGRID | FBgn0004391 |
11 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| TrEMBL data set | http://www.ebi.ac.uk/trembl/ |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| IntAct interactions data set | |
| BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster | |
| Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
7 Introns
19 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Lipid storage | shtd | none | 1.266656941 | 19067489 | |
| Lipid storage | shtd | none | -1.160707621 | 19067489 | |
| Lipid storage | shtd | none | -0.731476068 | 19067489 | |
| Lipid storage | shtd | none | 1.66557879 | 19067489 | |
| Cell size and cell-cycle regulation (1) | shtd | none | sp | 16496002 | |
| Microtubule assembly and organization | shtd | Abnormal spindle | np | 18463163 | |
| Mutant human huntingtin aggregation | shtd | Increased mutant human huntingtin aggregation | >= 2 | 19789644 | |
| Muscle morphogenesis and function (1) | shtd | none | np | 20220848 | |
| Heat nociception (1) | shtd | Developmentally lethal | 0 | 21074052 | |
| Heart development and function (1) | shtd | none | 1 | 20371351 | |
| Serratia marcescens infection (1) | shtd | none | 0.119047619047619 | 19520911 | |
| Notch pathway regulation (4) | shtd | Bristle morphology defects, notum malformation death | sp | 19363474 | |
| Self-renewal and differentiation in neural stem cells | shtd | GFP aggregates number, GFP aggregates size, neuroblast smaller cell size, neuroblast less large cells, ganglion mother cell shorter lineages, neuroblast loss, neuroblast loss with smaller neuroblast cell size, neuroblasts smaller, neuroblast underprolifer | sp | 21549331 | |
| Adiposity regulation (1) | shtd | Decreased triglyceride expression | -0.444 | 20074523 | |
| Adiposity regulation (2) | shtd | none | 0.118 | 20074523 | |
| Adiposity regulation (3) | shtd | none | -0.094 | 20074523 | |
| Adiposity regulation (4) | shtd | Decreased triglyceride expression | -0.986 | 20074523 | |
| Adiposity regulation (5) | shtd | none | -0.073 | 20074523 | |
| Hippo pathway regulation | shtd | none | -2.52 | 23263283 |
