Genomics
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9 Alleles
| DB identifier | Symbol | Allele Class | Organism |
|---|---|---|---|
| FBal0241450 | shtd[2] | Drosophila melanogaster | |
| FBal0241451 | shtd[3.gamma] | Drosophila melanogaster | |
| FBal0241453 | shtd[rescue.Scer\UAS] | Drosophila melanogaster | |
| FBal0258831 | shtd[KK100819] | Drosophila melanogaster | |
| FBal0140936 | shtd[1] | Drosophila melanogaster | |
| FBal0278862 | shtd[HMS01744] | Drosophila melanogaster | |
| FBal0287528 | shtd[Scer\UAS.ORF.T:Ivir\HA1] | Drosophila melanogaster | |
| FBal0210576 | shtd[GD14150] | Drosophila melanogaster | |
| FBal0198126 | shtd[3] | loss of function allele | Drosophila melanogaster |
11 Clones
| Secondary Identifier | DB identifier |
|---|---|
| DPiM_LD37115 | FBcl0740633 |
| DMG1-chrX.16.031.a | FBcl0361173 |
| EK286045 | FBcl0129248 |
| GM22507 | FBcl0144627 |
| GM29903 | FBcl0144629 |
| LD37115 | FBcl0171688 |
| RP004207999 | FBcl0503575 |
| CK01.14D.F7 | FBcl0435803 |
| 180906 | FBcl0435830 |
| 214565.29 | FBcl0435842 |
| 62021 | FBcl0435848 |
8 Exons
| DB identifier | Symbol |
|---|---|
| FBgn0004391:8 | shtd:8 |
| FBgn0004391:7 | shtd:7 |
| FBgn0004391:6 | shtd:6 |
| FBgn0004391:5 | shtd:5 |
| FBgn0004391:4 | shtd:4 |
| FBgn0004391:3 | shtd:3 |
| FBgn0004391:2 | shtd:2 |
| FBgn0004391:1 | shtd:1 |
2 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0074077-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0074077-3-prime-utr | Drosophila melanogaster |
Other
53 Pathways
- Amplification of signal from the kinetochores,
- Cyclin A/B1 associated events during G2/M transition,
- APC/C:Cdc20 mediated degradation of Cyclin B,
- APC-Cdc20 mediated degradation of Nek2A,
- Ubiquitin Mediated Degradation of Phosphorylated Cdc25A,
- G2/M DNA replication checkpoint,
- Cell Cycle,
- Homologous Recombination Repair,
- Double-Strand Break Repair,
- Cell Cycle Checkpoints,
- Mitotic Metaphase and Anaphase,
- Mitotic G1-G1/S phases,
- G2/M Checkpoints,
- DNA Replication,
- Senescence-Associated Secretory Phenotype (SASP),
- Cellular responses to stress,
- Cyclin A:Cdk2-associated events at S phase entry,
- Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins,
- p53-Independent G1/S DNA damage checkpoint,
- APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1,
- Inactivation of APC/C via direct inhibition of the APC/C complex,
- APC/C:Cdc20 mediated degradation of mitotic proteins,
- Phosphorylation of the APC/C,
- Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components,
- Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal,
- Mitotic M-M/G1 phases,
- APC/C:Cdc20 mediated degradation of Securin,
- Mitotic Spindle Checkpoint,
- Homologous recombination repair of replication-independent double-strand breaks,
- Mitotic Anaphase,
- ATM mediated response to DNA double-strand break,
- G2/M Transition,
- Regulation of mitotic cell cycle,
- Cellular Senescence,
- p53-Independent DNA Damage Response,
- APC/C-mediated degradation of cell cycle proteins,
- SCF(Skp2)-mediated degradation of p27/p21,
- Cell Cycle, Mitotic,
- Cyclin E associated events during G1/S transition,
- S Phase,
- M Phase,
- Polo-like kinase mediated events,
- Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase,
- Cdc20:Phospho-APC/C mediated degradation of Cyclin A,
- Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex,
- G2/M DNA damage checkpoint,
- Separation of Sister Chromatids,
- G1/S Transition,
- Autodegradation of Cdh1 by Cdh1:APC/C,
- Regulation of APC/C activators between G1/S and early anaphase,
- G1/S DNA Damage Checkpoints,
- Mitotic G2-G2/M phases,
- DNA Repair
2 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 32473 | NCBI Entrez Gene identifiers | FBgn0004391 |
| 58826 | BioGRID | FBgn0004391 |
11 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| TrEMBL data set | http://www.ebi.ac.uk/trembl/ |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| IntAct interactions data set | |
| BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster | |
| Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
7 Introns
19 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Lipid storage | shtd | none | 1.266656941 | 19067489 | |
| Lipid storage | shtd | none | -1.160707621 | 19067489 | |
| Lipid storage | shtd | none | -0.731476068 | 19067489 | |
| Lipid storage | shtd | none | 1.66557879 | 19067489 | |
| Cell size and cell-cycle regulation (1) | shtd | none | sp | 16496002 | |
| Microtubule assembly and organization | shtd | Abnormal spindle | np | 18463163 | |
| Mutant human huntingtin aggregation | shtd | Increased mutant human huntingtin aggregation | >= 2 | 19789644 | |
| Muscle morphogenesis and function (1) | shtd | none | np | 20220848 | |
| Heat nociception (1) | shtd | Developmentally lethal | 0 | 21074052 | |
| Heart development and function (1) | shtd | none | 1 | 20371351 | |
| Serratia marcescens infection (1) | shtd | none | 0.119047619047619 | 19520911 | |
| Notch pathway regulation (4) | shtd | Bristle morphology defects, notum malformation death | sp | 19363474 | |
| Self-renewal and differentiation in neural stem cells | shtd | GFP aggregates number, GFP aggregates size, neuroblast smaller cell size, neuroblast less large cells, ganglion mother cell shorter lineages, neuroblast loss, neuroblast loss with smaller neuroblast cell size, neuroblasts smaller, neuroblast underprolifer | sp | 21549331 | |
| Adiposity regulation (1) | shtd | Decreased triglyceride expression | -0.444 | 20074523 | |
| Adiposity regulation (2) | shtd | none | 0.118 | 20074523 | |
| Adiposity regulation (3) | shtd | none | -0.094 | 20074523 | |
| Adiposity regulation (4) | shtd | Decreased triglyceride expression | -0.986 | 20074523 | |
| Adiposity regulation (5) | shtd | none | -0.073 | 20074523 | |
| Hippo pathway regulation | shtd | none | -2.52 | 23263283 |
