Genomics
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17 Alleles
| DB identifier | Symbol | Allele Class | Organism |
|---|---|---|---|
| FBal0120639 | alph[XS-88] | Drosophila melanogaster | |
| FBal0120642 | alph[S-292] | Drosophila melanogaster | |
| FBal0120641 | alph[S-331] | Drosophila melanogaster | |
| FBal0120640 | alph[S-355] | Drosophila melanogaster | |
| FBal0161962 | alph[c04528] | Drosophila melanogaster | |
| FBal0245484 | alph[JF01192] | Drosophila melanogaster | |
| FBal0212516 | alph[MB01683] | Drosophila melanogaster | |
| FBal0286039 | alph[MI08597] | Drosophila melanogaster | |
| FBal0186697 | alph[f05750] | Drosophila melanogaster | |
| FBal0186698 | alph[f03783] | Drosophila melanogaster | |
| FBal0209057 | alph[GD8826] | Drosophila melanogaster | |
| FBal0279152 | alph[HMS02040] | Drosophila melanogaster | |
| FBal0288395 | alph[GMR] | Drosophila melanogaster | |
| FBal0288396 | alph[S-331.GMR] | Drosophila melanogaster | |
| FBal0288397 | alph[dsRNA.Scer\UAS] | Drosophila melanogaster | |
| FBal0235126 | alph[KK107730] | Drosophila melanogaster | |
| FBal0272972 | alph[NIG.1906R] | Drosophila melanogaster |
178 Clones
14 Exons
| DB identifier | Symbol |
|---|---|
| FBgn0086361:13 | alph:13 |
| FBgn0086361:14 | alph:14 |
| FBgn0086361:2 | alph:2 |
| FBgn0086361:3 | alph:3 |
| FBgn0086361:1 | alph:1 |
| FBgn0086361:4 | alph:4 |
| FBgn0086361:5 | alph:5 |
| FBgn0086361:6 | alph:6 |
| FBgn0086361:7 | alph:7 |
| FBgn0086361:8 | alph:8 |
| FBgn0086361:9 | alph:9 |
| FBgn0086361:10 | alph:10 |
| FBgn0086361:11 | alph:11 |
| FBgn0086361:12 | alph:12 |
6 Transcripts
| DB identifier | Gene |
|---|---|
| FBtr0085444 | alph |
| FBtr0085445 | alph |
| FBtr0085446 | alph |
| FBtr0309241 | alph |
| FBtr0085442 | alph |
| FBtr0085443 | alph |
12 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0309241-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0085442-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0085443-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0085444-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0085445-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0085446-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0309241-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0085442-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0085443-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0085444-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0085445-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0085446-3-prime-utr | Drosophila melanogaster |
Other
44 Pathways
- Loss of Function of TGFBR2 in Cancer,
- TGFBR2 MSI Frameshift Mutants in Cancer,
- Generic Transcription Pathway,
- Developmental Biology,
- Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer,
- TGF-beta receptor signaling activates SMADs,
- PI3K Cascade,
- TGFBR1 LBD Mutants in Cancer,
- Signaling by TGF-beta Receptor Complex in Cancer,
- Energy dependent regulation of mTOR by LKB1-AMPK,
- Signaling Pathways,
- DINR-mediated activation,
- TOR signaling pathway,
- Signaling by NODAL,
- Regulation of AMPK activity via LKB1,
- PKB-mediated events,
- SMAD2/3 MH2 Domain Mutants in Cancer,
- Signaling by TGF-beta Receptor Complex,
- SMAD4 MH2 Domain Mutants in Cancer,
- Insulin receptor recycling,
- Regulation of Rheb GTPase activity by AMPK,
- IRS-related events triggered by IGF1R,
- Signaling by Activin,
- IRS-related events,
- Downregulation of SMAD2/3:SMAD4 transcriptional activity,
- SMAD2/3 Phosphorylation Motif Mutants in Cancer,
- IRS activation,
- Loss of Function of SMAD4 in Cancer,
- IGF1R signaling cascade,
- Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R),
- Gene Expression,
- Release of eIF4E,
- Loss of Function of SMAD2/3 in Cancer,
- Loss of Function of TGFBR1 in Cancer,
- Insulin signaling pathway,
- TGFBR1 KD Mutants in Cancer,
- Disease,
- TGFBR2 Kinase Domain Mutants in Cancer,
- mTOR signalling,
- Insulin receptor mediated signaling,
- mTORC1-mediated signalling,
- SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription,
- Insulin receptor signalling cascade,
- IRS-mediated signalling
2 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 43481 | NCBI Entrez Gene identifiers | FBgn0086361 |
| 68345 | BioGRID | FBgn0086361 |
11 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| TrEMBL data set | http://www.ebi.ac.uk/trembl/ |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| IntAct interactions data set | |
| BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster | |
| Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
14 Introns
26 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Lipid storage | alph | none | -1.865377413 | 19067489 | |
| Lipid storage | alph | none | -0.674490759 | 19067489 | |
| Cell size and cell-cycle regulation (1) | alph | none | sp | 16496002 | |
| Cell size and cell-cycle regulation (1) | alph | none | sp | 16496002 | |
| Mitochondrial biogenesis and function | alph | Decreased mitochondrial citrate synthase activity | 0.715 | 18042644 | |
| Muscle morphogenesis and function (1) | alph | none | np | 20220848 | |
| Heat nociception (1) | alph | none | 0.01 | 21074052 | |
| Heart development and function (1) | alph | none | 1 | 20371351 | |
| Serratia marcescens infection (1) | alph | none | -0.11 | 19520911 | |
| Notch pathway regulation (4) | alph | none | 0 | 19363474 | |
| PGN-induced dJNK phosphorylation | alph | Increased P-JNK protein expression with PGN | 2.26 | 15 min PGN induction | 19893628 |
| Notch pathway regulation (1) | alph | Downregulation of Notch pathway | np | 20493818 | |
| Notch pathway regulation (2) | alph | none | np | en-GAL4 | 20493818 |
| Notch pathway regulation (2) | alph | none | np | en-GAL4 | 20493818 |
| Notch pathway regulation (3) | alph | Only lethal with Notch | np | 20493818 | |
| Adiposity regulation (1) | alph | none | -0.192 | 20074523 | |
| Blood cell homeostasis regulation (1) | alph | none | np | 20540764 | |
| Blood cell homeostasis regulation (2) | alph | none | np | 20540764 | |
| Vaccinia virus infection | alph | none | sp | 20585561 | |
| RTK-Ras-ERK pathway regulation (1) | alph | none | 1.34 | 0 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (1) | alph | none | 0.73 | 10 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | alph | none | 0.3 | 10 minutes sSpitz stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | alph | Increased ERK phosphorylation after sSpitz and EGF stimulation | 1.52 | 30 minutes sSpitz stimulation | 22028469 |
| Hippo pathway regulation | alph | none | 0.19 | 23263283 | |
| Glycosylation regulation (1) | alph | none | sp | 21203496 | |
| Huntingtin (Htt) aggregates formation | alph | Increased formation of mutant Huntingtin (Httex1-Qn) protein aggregates | np | 20100940 |
