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Gene : foxo D. melanogaster

DB identifier  ? FBgn0038197 Secondary Identifier  ? CG3143
Name  ? forkhead box, sub-group O Source  FlyBase
  • synonyms:
  • foxo|dFOXO,
  • 3143,
  • FBan0003143,
  • Q95V55,
  • forkhead box sub-group O,
  • Forkhead Box O,
  • anon-WO0118547.374,
  • Forkhead box,
  • Forkhead box type O,
  • FBgn0062059,
  • forkhead box, subgroup O,
  • FKHR,
  • forkhead transcription factor,
  • FBgn0038197,
  • fd88A,
  • Dfoxo,
  • Forkhead bOX-containing protein, subfamily O,
  • forkhead box-containing protein, O subfamily,
  • FOXO,
  • Afx,
  • CG3143,
  • DmQ95V5

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53 Alleles

DB identifier Symbol Allele Class Organism
FBal0277816 foxo[25J13]   Drosophila melanogaster
FBal0247068 foxo[MI00786]   Drosophila melanogaster
FBal0270116 foxo[Scer\UAS.cTa]   Drosophila melanogaster
FBal0270117 foxo[GS1664]   Drosophila melanogaster
FBal0270118 foxo[Delta2]   Drosophila melanogaster
FBal0270262 foxo[T:SV5\V5]   Drosophila melanogaster
FBal0282589 foxo[Scer\UAS.P\T.T:Avic\GFP]   Drosophila melanogaster
FBal0179838 foxo[W24]   Drosophila melanogaster
FBal0179839 foxo[EY16506]   Drosophila melanogaster
FBal0179834 foxo[d08413]   Drosophila melanogaster
FBal0179830 foxo[f05979]   Drosophila melanogaster
FBal0179833 foxo[e01448]   Drosophila melanogaster
FBal0179835 foxo[c05865]   Drosophila melanogaster
FBal0197831 foxo[Scer\UAS.T:Avic\GFP]   Drosophila melanogaster
FBal0179836 foxo[c02768]   Drosophila melanogaster
FBal0257474 foxo[HMS00793]   Drosophila melanogaster
FBal0179831 foxo[f00765]   Drosophila melanogaster
FBal0179832 foxo[e01988]   Drosophila melanogaster
FBal0179837 foxo[c01841]   Drosophila melanogaster
FBal0151930 foxo[21] loss of function allele Drosophila melanogaster
FBal0151928 foxo[EP35-147]   Drosophila melanogaster
FBal0151929 foxo[25] loss of function allele Drosophila melanogaster
FBal0243120 foxo[MI00493]   Drosophila melanogaster
FBal0278192 foxo[Scer\UAS.cLa]   Drosophila melanogaster
FBal0268859 foxo[T:Avic\GFP-SF,T:Zzzz\FLAG]   Drosophila melanogaster
FBal0285866 foxo[Scer\UAS.cWa.T:Avic\GFP]   Drosophila melanogaster
FBal0267690 foxo[S259A.Scer\UAS]   Drosophila melanogaster
FBal0267691 foxo[S259E.Scer\UAS]   Drosophila melanogaster
FBal0267692 foxo[Scer\UAS.cKb]   Drosophila melanogaster
FBal0269838 foxo[Delta94]   Drosophila melanogaster

55 Clones

Secondary Identifier DB identifier
EK296112 FBcl0024862
EK038348 FBcl0024936
EK115937 FBcl0025096
EK199820 FBcl0025104
EK187801 FBcl0025118
EK213838 FBcl0025132
EK177710 FBcl0025162
EK056705 FBcl0025166
EK175147 FBcl0025180
EK175036 FBcl0025184
EK160721 FBcl0025204
EK039347 FBcl0025208
EK304860 FBcl0025568
AT07448 FBcl0043609
EC26030 FBcl0073159
EP01961 FBcl0089377
GH06052 FBcl0128995
GM05512 FBcl0143640
LD19191 FBcl0160281
LD14524 FBcl0160293
LD05569 FBcl0160295
LD18492 FBcl0160304
LD45950 FBcl0175656
LD45953 FBcl0175672
RE61938 FBcl0228256
RE06920 FBcl0228261
RE55470 FBcl0228399
RE37019 FBcl0228455
RE04627 FBcl0228470
RE28107 FBcl0228479

16 Exons

DB identifier Symbol
FBgn0038197:4 foxo:4
FBgn0038197:1 foxo:1
FBgn0038197:3 foxo:3
FBgn0038197:7 foxo:7
FBgn0038197:8 foxo:8
FBgn0038197:9 foxo:9
FBgn0038197:10 foxo:10
FBgn0038197:11 foxo:11
FBgn0038197:12 foxo:12
FBgn0038197:13 foxo:13
FBgn0038197:15 foxo:15
FBgn0038197:16 foxo:16
FBgn0038197:2 foxo:2
FBgn0038197:5 foxo:5
FBgn0038197:14 foxo:14
FBgn0038197:6 foxo:6

4 Transcripts

DB identifier Gene
FBtr0082887 foxo
FBtr0305052 foxo
FBtr0337094 foxo
FBtr0082886 foxo

8 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0305052-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0082886-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0082887-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0337094-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0305052-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0082886-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0082887-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0337094-3-prime-utr Drosophila melanogaster

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70 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
41709 NCBI Entrez Gene identifiers FBgn0038197
66786 BioGRID FBgn0038197

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0038197 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1830.0
FBgn0038197 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 1582.0
FBgn0038197 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1406.0
FBgn0038197 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1469.0
FBgn0038197 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1670.0
FBgn0038197 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 1132.0
FBgn0038197 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 1325.0
FBgn0038197 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 5413.0
FBgn0038197 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 394.0
FBgn0038197 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1327.0
FBgn0038197 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1379.0
FBgn0038197 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 1461.0
FBgn0038197 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 3854.0
FBgn0038197 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 1432.0
FBgn0038197 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 2258.0
FBgn0038197 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 1619.0
FBgn0038197 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1294.0
FBgn0038197 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1689.0
FBgn0038197 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1659.0
FBgn0038197 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1565.0
FBgn0038197 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 2519.0
FBgn0038197 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 2592.0
FBgn0038197 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 902.0
FBgn0038197 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 695.0
FBgn0038197 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1752.0
FBgn0038197 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 2204.0
FBgn0038197 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 753.0
FBgn0038197 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 310.0
FBgn0038197 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 511.0
FBgn0038197 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 546.0

17 Introns

DB identifier
Organism . Name
intron_FBgn0038197:1_FBgn0038197:3 Drosophila melanogaster
intron_FBgn0038197:3_FBgn0038197:7 Drosophila melanogaster
intron_FBgn0038197:7_FBgn0038197:8 Drosophila melanogaster
intron_FBgn0038197:8_FBgn0038197:9 Drosophila melanogaster
intron_FBgn0038197:9_FBgn0038197:10 Drosophila melanogaster
intron_FBgn0038197:10_FBgn0038197:11 Drosophila melanogaster
intron_FBgn0038197:11_FBgn0038197:12 Drosophila melanogaster
intron_FBgn0038197:12_FBgn0038197:13 Drosophila melanogaster
intron_FBgn0038197:13_FBgn0038197:15 Drosophila melanogaster
intron_FBgn0038197:15_FBgn0038197:16 Drosophila melanogaster
intron_FBgn0038197:2_FBgn0038197:5 Drosophila melanogaster
intron_FBgn0038197:5_FBgn0038197:7 Drosophila melanogaster
intron_FBgn0038197:12_FBgn0038197:14 Drosophila melanogaster
intron_FBgn0038197:14_FBgn0038197:15 Drosophila melanogaster
intron_FBgn0038197:1_FBgn0038197:4 Drosophila melanogaster
intron_FBgn0038197:4_FBgn0038197:7 Drosophila melanogaster
intron_FBgn0038197:6_FBgn0038197:7 Drosophila melanogaster

19 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage foxo none -0.309590163   19067489
Lipid storage foxo none 0.091373456   19067489
Lipid storage foxo none 0.701686253   19067489
Lipid storage foxo none -0.522194987   19067489
Constitutive protein secretion and Golgi organization (1) foxo Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) foxo none sp   16496002
Ca2+ channel regulation foxo Decreased Ca2+ influx 3   16645049
Dendrite pattern formation foxo none np   16547170
Combinatorial effect with methyl methanesulphonate (2) foxo none sp   19543366
Heat nociception (1) foxo none -1.17   21074052
Heat nociception (1) foxo none -0.4   21074052
Heat nociception (1) foxo none -1.17   21074052
Heat nociception (1) foxo none -0.4   21074052
Heart development and function (1) foxo none 0.9   20371351
Serratia marcescens infection (1) foxo none -1.74489795918367   19520911
Akt-TOR pathway negative feedback regulation foxo Decreased dAkt phosphorylation after insulin stimulation -2.7 10 min insulin stimulation 20585550
RTK-Ras-ERK pathway regulation (2) foxo Decreased ERK phosphorylation after sSpitz and EGF stimulation -2.31 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) foxo none -0.36 30 minutes sSpitz stimulation 22028469
Hippo pathway regulation foxo none 0.18   23263283

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