Genomics
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8 Alleles
| DB identifier | Symbol | Allele Class | Organism |
|---|---|---|---|
| FBal0266256 | RpL3[GL00556] | Drosophila melanogaster | |
| FBal0196047 | RpL3[e03180] | Drosophila melanogaster | |
| FBal0259769 | RpL3[KK109091] | Drosophila melanogaster | |
| FBal0137383 | RpL3[KG05440] | Drosophila melanogaster | |
| FBal0287514 | RpL3[Scer\UAS.ORF.T:Ivir\HA1] | Drosophila melanogaster | |
| FBal0208345 | RpL3[GD13494] | Drosophila melanogaster | |
| FBal0208346 | RpL3[GD16490] | Drosophila melanogaster | |
| FBal0241628 | RpL3[G13893] | Drosophila melanogaster |
1305 Clones
9 Exons
| DB identifier | Symbol |
|---|---|
| FBgn0020910:1 | RpL3:1 |
| FBgn0020910:2 | RpL3:2 |
| FBgn0020910:4 | RpL3:4 |
| FBgn0020910:3 | RpL3:3 |
| FBgn0020910:6 | RpL3:6 |
| FBgn0020910:7 | RpL3:7 |
| FBgn0020910:8 | RpL3:8 |
| FBgn0020910:5 | RpL3:5 |
| FBgn0020910:9 | RpL3:9 |
4 Transcripts
| DB identifier | Gene |
|---|---|
| FBtr0082347 | RpL3 |
| FBtr0082346 | RpL3 |
| FBtr0302586 | RpL3 |
| FBtr0336783 | RpL3 |
8 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0082347-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0082346-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0302586-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0336783-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0082347-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0082346-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0302586-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0336783-3-prime-utr | Drosophila melanogaster |
Other
49 Pathways
- RNA Polymerase II Transcription Initiation And Promoter Clearance,
- Processing of Intronless Pre-mRNAs,
- Processing of Capped Intronless Pre-mRNA,
- Metabolism of mRNA,
- SRP-dependent cotranslational protein targeting to membrane,
- 3' -UTR-mediated translational regulation,
- Cap-dependent Translation Initiation,
- RNA Polymerase II Transcription Termination,
- Formation of the Early Elongation Complex,
- SLBP independent Processing of Histone Pre-mRNAs,
- Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S,
- RNA Polymerase II Transcription Initiation,
- RNA Polymerase II Pre-transcription Events,
- Post-Elongation Processing of Intronless pre-mRNA,
- Transcription,
- Eukaryotic Translation Elongation,
- RNA Pol II CTD phosphorylation and interaction with CE,
- SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs,
- Cleavage of Growing Transcript in the Termination Region,
- Nonsense Mediated Decay Independent of the Exon Junction Complex,
- Transport of the SLBP Dependant Mature mRNA,
- Transport of Mature Transcript to Cytoplasm,
- Transport of the SLBP independent Mature mRNA,
- Processing of Capped Intron-Containing Pre-mRNA,
- Transport of Mature mRNA derived from an Intron-Containing Transcript,
- Transport of Mature mRNA Derived from an Intronless Transcript,
- Formation of a pool of free 40S subunits,
- Nonsense Mediated Decay Enhanced by the Exon Junction Complex,
- Ribosomal scanning and start codon recognition,
- RNA Polymerase II Transcription,
- Metabolism of proteins,
- Translation,
- Formation of RNA Pol II elongation complex,
- RNA Polymerase II Transcription Elongation,
- RNA Polymerase II Transcription Pre-Initiation And Promoter Opening,
- Transport of Mature mRNAs Derived from Intronless Transcripts,
- GTP hydrolysis and joining of the 60S ribosomal subunit,
- Peptide chain elongation,
- Elongation arrest and recovery,
- Post-Elongation Processing of the Transcript,
- RNA Polymerase II Promoter Escape,
- mRNA Capping,
- Metabolism of RNA,
- L13a-mediated translational silencing of Ceruloplasmin expression,
- mRNA Processing,
- Gene Expression,
- Nonsense-Mediated Decay,
- Eukaryotic Translation Termination,
- Eukaryotic Translation Initiation
2 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 41347 | NCBI Entrez Gene identifiers | FBgn0020910 |
| 66481 | BioGRID | FBgn0020910 |
11 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| Swiss-Prot data set | http://ca.expasy.org/sprot |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| IntAct interactions data set | |
| BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster | |
| Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
9 Introns
36 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Lipid storage | RpL3 | Increased lipid droplet area | 2.350092405 | 19067489 | |
| Lipid storage | RpL3 | Increased lipid droplet area | 2.844190652 | 19067489 | |
| ERK signaling | RpL3 | ERK activation reduced | weak | 17086199 | |
| Drosophila C virus infection | RpL3 | Drosophila C virus replication down | np | 17040126 | |
| Cytokinesis regulation | RpL3 | Binucleate cells with decreased viability | medium | 15547975 | |
| Drosophila C virus infection | RpL3 | Drosophila C virus infection reduced | np | 15713840 | |
| Hedgehog signaling | RpL3 | Decreased Hedgehog reporter activity | -2.67 | 16311596 | |
| Constitutive protein secretion and Golgi organization (1) | RpL3 | Decreased horseradish peroxidase protein expression | sp | 16452979 | |
| Cell size and cell-cycle regulation (1) | RpL3 | Decreased viability | sp | 16496002 | |
| Cell size and cell-cycle regulation (2) | RpL3 | none | 1.264 | 16496002 | |
| Cell size and cell-cycle regulation (3) | RpL3 | none | 494 | 16496002 | |
| Candida albicans phagocytosis (1) | RpL3 | none | np | 16336044 | |
| Mitochondrial biogenesis and function | RpL3 | Increased mitochondrial citrate synthase activity, decreased viability | 1.18 | 18042644 | |
| Muscle morphogenesis and function (1) | RpL3 | Lethal | np | 20220848 | |
| Muscle morphogenesis and function (1) | RpL3 | Lethal | np | 20220848 | |
| Muscle morphogenesis and function (3) | RpL3 | Split myofibril, fading Z-line | np | 20220848 | |
| Heat nociception (1) | RpL3 | Increased noxious heat avoidance, lethal | 1.71 | 21074052 | |
| Heat nociception (1) | RpL3 | none | 0.24 | 21074052 | |
| Heart development and function (1) | RpL3 | Larval lethal | 0 | 20371351 | |
| Serratia marcescens infection (1) | RpL3 | none | -0.298701298701298 | 19520911 | |
| Serratia marcescens infection (1) | RpL3 | none | -0.878378378378378 | 19520911 | |
| Notch pathway regulation (4) | RpL3 | none | 0 | 19363474 | |
| Notch pathway regulation (4) | RpL3 | Completely lethal (before pupal) | sp | 19363474 | |
| Notch pathway regulation (4) | RpL3 | Completely lethal (pupal) | sp | 19363474 | |
| Hh pathway regulation | RpL3 | Downregulation of Hh pathway | -0.40197312267493 | 17903264 | |
| Notch pathway regulation (1) | RpL3 | Downregulation of Notch pathway | np | 20493818 | |
| Adiposity regulation (1) | RpL3 | none | -0.16 | 20074523 | |
| Adiposity regulation (1) | RpL3 | none | 0.094 | 20074523 | |
| Blood cell homeostasis regulation (1) | RpL3 | none | np | 20540764 | |
| Blood cell homeostasis regulation (2) | RpL3 | none | np | 20540764 |
